کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8553829 | 1562693 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antimicrobial and cytotoxic effects of denture base acrylic resin impregnated with cleaning agents after long-term immersion
ترجمه فارسی عنوان
اثرات ضد میکروبی و سیتوتوکسیک رزین اکریلیک پایه دندان مصنوعی با مواد تمیزکننده پس از غوطه ور شدن طولانی مدت
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کلمات کلیدی
رزین اکریلیک دندان مصنوعی، پاک کننده های شیمیایی دندانپزشکی، غرق شدن درازمدت، بقای شیمیایی، اثر ضد میکروبی، سمیت مسمومیت،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
The coadjutant method for denture cleansing most used by denture wearers is immersion in chemical agents, which are toxic when in direct contact with cells. However, clinically, the contact between these chemical agents and prosthetic tissues does not occur directly, but rather with what remained impregnated into acrylic bases, even after rinsing the disinfected dentures. This study evaluated the antimicrobial and cytotoxic effects of a denture acrylic resin after successive cycles of daily overnight immersion in 1% sodium hypochlorite (1%NaClO) and 2% chlorhexidine digluconate (2%CHX), simulating the periods of 9â¯months or 1.5â¯year. Microbiological and cytotoxic assays were performed, respectively, by broth microdilution method (Candida albicans or Staphylococcus aureus) and MTT assay. Chemical residues of 2%CHX impregnated into the denture acrylic resin had an antimicrobial effect on both immersion periods, which was not observed with those of 1%NaClO. However, residues of 2%CHX were severely cytotoxic to human gingival fibroblasts compared to those of 1%NaClO and acrylic resin (not submitted to the denture cleansers), which were slightly cytotoxic. Even at low concentrations recommended for overnight soaking of removable dentures, the chemical residues of CHX may result in some degree of toxicity to the denture-bearing mucosa after long-term daily immersion.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology in Vitro - Volume 52, October 2018, Pages 8-13
Journal: Toxicology in Vitro - Volume 52, October 2018, Pages 8-13
نویسندگان
A.L.F. Procópio, R.A. da Silva, J.G. Maciel, C.Y.C. Sugio, S. Soares, V.M. Urban, K.H. Neppelenbroek,