کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8684835 1580202 2018 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
IDH-wildtype infiltrative low-grade glial tumor with nodule-like enhancement pattern
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
IDH-wildtype infiltrative low-grade glial tumor with nodule-like enhancement pattern
چکیده انگلیسی
The authors describe a usual case of infiltrative low-grade glial neoplasm with a marked enhanced area which is difficult to diagnose. A 42-year-old man had the diffuse mass lesion partially with apparent enhancement in the right temporal lobe, the insular, and the basal ganglia regions. Final pathological diagnosis from the removed specimens was IDH-wildtype diffuse astrocytoma according to 2016 WHO classification, although it had unusual findings including gliomesenchymal reaction. The nodule-like enhancement was thought to be owing to the mesenchymal component. Several molecular analysis including pyrosequence analysis, Ion Torrent™ next-generation sequencing and multiplex ligation-dependent probe amplification analysis detected no genomic abnormality. IDH-wildtype diffuse astrocytoma is a heterogeneous category and has a minor subset with a silent genomic landscape like the present case.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Interdisciplinary Neurosurgery - Volume 14, December 2018, Pages 111-114
نویسندگان
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