کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8744089 | 1592737 | 2018 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Dynamics of humoral response in naturally-infected cattle after vaccination against leptospirosis
ترجمه فارسی عنوان
دینامیک پاسخ هومورال در گاوهای آلوده به طبیعت پس از واکسیناسیون علیه لپتوسپیروز
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کلمات کلیدی
لپتوسپیرا، واکسن، گاو، ایمونوگلوبولین، باکتری
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
انگل شناسی
چکیده انگلیسی
Vaccination is one of the most important measures for the control of bovine leptospirosis. Despite the broad usage of vaccination against leptospirosis in cattle worldwide, the dynamics of the post-vaccine immune response remain controversial and many aspects are still unclear, particularly in naturally-infected animals. Thus, the objective of this study is to describe the dynamics of humoral response in naturally-infected cattle after vaccination against leptospirosis. A total of 162 cows were studied, consisting of 129 included in the experimental group (G1), and subdivided into two groups, vaccinated with two different brands of bacterins, as well as 33 in the control group (G2). Serology (MAT) was performed in all cows on D0 (vaccination), then 60 and 120 days post-vaccination. Vaccination significantly elicited the production of anti-leptospiral antibodies. Seroreactivity increased rapidly but was of short duration (up to D60). Significantly, that increase was notably higher in the vaccinated group than in the controlled. Both vaccines elicited a similar response with a higher rate of seroreactive animals, but predominately against different serogroups. In this context, our results reinforce that, although of limited duration, vaccination against leptospirosis significantly elicits a specific humoral response in naturally-infected animals. The two studied vaccines presented similar seroconversion levels, but predominantly to different serogroups, being one against Icterohaemorrhagiae and the other against Sejroe.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Tropica - Volume 187, November 2018, Pages 87-91
Journal: Acta Tropica - Volume 187, November 2018, Pages 87-91
نویسندگان
Gabriel Martins, Clara Slade Oliveira, Walter Lilenbaum,