کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8745753 | 1593187 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characteristics of mucoid Streptococcus pyogenes isolated from two patients with pneumonia in a local community
ترجمه فارسی عنوان
ویژگی های استرپتوکوکوس پیوژنز موکوئید جدا شده از دو بیمار مبتلا به پنومونی در یک جامعه محلی
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کلمات کلیدی
استرپتوکوک پیتوژنز، ذات الریه، جامعه محلی، کشش موکوئید،
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
چکیده انگلیسی
Streptococcus pyogenes (Group A Streptococcus, GAS) infections can develop into life-threatening disorders. However, the occurrence of some GAS pneumonia cases is relatively rare in a local community. We report here characteristics of mucoid GAS isolates obtained from the sputum of two patients with pneumonia in a local community. Although case-patients did not have contact with each other, case-patient 1â²s child and case-patient 2â²s grandchild attended the same kindergarten where a GAS pharyngitis epidemic had occurred. We conducted phenotypic and genotypic analyses with the GAS isolates from sputum of both patients, to examine (1) colony appearance between the isolates, (2) numerical profile based on API-20 Strep system, (3) similarity to the type strain using 16S rRNA sequencing, (4) emm type (subtype) and emm full-length sequence, (5) sequence type, (6) sic allele, (7) antimicrobial susceptibility result and the resistance determinant, (8) genome profile following a random amplified polymorphic DNA fragments, and (9) pattern of digested DNA fragments by pulse-field gel electrophoresis. These phenotypic and genotypic analyses revealed similar matching between the isolates from both cases. Our findings suggest that when clinicians examine adult patients having infection with the mucoid GAS, they should confirm whether anyone within the same household also developed the infection and need to investigate epidemic situations in local communities, including kindergartens and elementary schools.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: IDCases - Volume 6, 2016, Pages 43-46
Journal: IDCases - Volume 6, 2016, Pages 43-46
نویسندگان
Nobuaki M.D. Ph. D, Sakiko Hosoo, Yoshitaka Oyamada, Yasushi Sera, Yasuhiro Yamada, Momoko Sugawara, Akiko Higuchi, Yasuko Aoki, Takashi Takahashi,