کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8770118 1598520 2018 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Botulinum toxin and benign prostatic hyperplasia
ترجمه فارسی عنوان
توکسین بوتولینوم و هیپرپلازی خوش خیم پروستات
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
چکیده انگلیسی
Benign prostatic hyperplasia (BPH) is a clinical condition where lower urinary tract symptoms are caused by both a physically obstructing prostate as well as tight smooth muscles around the bladder outlet. Treatment of this condition with botulinum toxin has been used since 2003, but this interest has somewhat died down after two large randomized controlled trials (RCTs) showing equivalence of results between their treatment and placebo arms. However, with review of animal studies and unexplained exaggerated effect of the placebo arms of the two RCTs, together with recent data of sustained benefits after 18 months of treatment, the place of botulinum toxin in the BPH field is probably still present.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Journal of Urology - Volume 5, Issue 1, January 2018, Pages 33-36
نویسندگان
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