کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8786777 1601338 2018 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neoadjuvant and adjuvant strategies in retroperitoneal sarcoma
ترجمه فارسی عنوان
استراتژیهای غربالگری و عوارض جانبی در سارکوما عقبگردان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی
Extended surgery remains the mainstay of treatment in retroperitoneal sarcoma, although conflicting data exist on the benefit of neoadjuvant and adjuvant therapies, particularly with regard to tumour grade and histological type. Experience of radiotherapy and chemotherapy in extremity soft tissue sarcoma can inform treatment strategies, however these data cannot be universally extrapolated to the retroperitoneum where disease biology and anatomical considerations are different. The present review sets a historical context before discussing recent evidence and on-going multi-centre trials in retroperitoneal sarcoma. Promising data on histologically- and molecularly-targeted chemotherapy are discussed and the need for centralisation of retroperitoneal sarcoma services in order to facilitate large international collaborative trials is emphasised.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Surgical Oncology - Volume 44, Issue 5, May 2018, Pages 571-579
نویسندگان
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