Role of non-coding RNAs in cardiotoxicity of chemotherapy

This review illustrated that the molecular mechanisms of ncRNAs to regulate gene expression (figure. left) and mainly encapsulates that ncRNAs and correlative proteins involve in the orchestration of myocardial function (cardiomyocytes membrane channel currents and mitochondrial function) and cellular process (autophagy, apoptosis and senescence), together with the ncRNAs as candidate biomarkers (figure.right).289