The diagnostic efficacy of apparent diffusion coefficient value and Choline/Creatine ratio in differentiation between parotid gland tumors

Pleomorphic adenomas had highest ADC values and Warthin tumors had highest Cho/Cr ratios. ADC value had the best diagnostic performance in differentiating pleomorphic adenomas from Warthin tumors by using cutoff value 1.12 × 10−3 mm2/sec with sensitivity, specificity, PPV, NPV and accuracy 100% for each. ADC value × Cho/Cr ratio had the best diagnostic performance in differentiating malignant from benign tumors, malignant tumors from pleomorphic adenoma and malignant from Warthin's tumors by using cutoff value 2.37 at which sensitivity, specificity, PPV, NPV and accuracy all were 100%. Conclusion: ADC value and Cho/Cr ratio are useful in differentiating different pathological subtypes of parotid tumors.