کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8942941 | 1645123 | 2018 | 24 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Chitosan nanoparticles via high-pressure homogenization-assisted miniemulsion crosslinking for mixed-matrix membrane adsorbers
ترجمه فارسی عنوان
نانوذرات کیتوزان با استفاده از روش ترکیبی کمپلکس با استفاده از همگن سازی فشار بالا برای جذب غشای ماتریکس مخلوط
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
چکیده انگلیسی
Glutaraldehyde-crosslinked chitosan nanoparticles (Chi-NPs) were prepared reproducibly via miniemulsion crosslinking for effective adsorption of the active pharmaceutical ingredient (API) Diclofenac (DCL). Three different molecular weights (MWs) of highly deacetylated (>90%) chitosans (low, medium and high MW) were used to vary the disperse phase viscosity. Particle formation was evaluated ranging from one to seven homogenization cycles at 40â¯MPa. Particles were prepared successfully with the low and medium MW chitosan in the range of 125â¯nm-250â¯nm (z-average). In HPLC assisted, static adsorption experiments, all particles showed a rapid sorption rate (<2â¯min) with an adsorption capacity of up to 256.2â¯mgâ¯gâ1 DCL. Modelling of adsorption isotherms resulted in a qmax 358.3â¯mgâ¯g-1 for Langmuir and 502.5â¯mgâ¯gâ1 for Sips, respectively. Membrane adsorbers were prepared by processing Chi-NPs into porous polyether sulfone microfiltration membranes via a casting and phase inversion process, resulting in an adsorption capacity of up to 3.6â¯mgâ¯m-2 DCL in dynamic adsorption experiments.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 201, 1 December 2018, Pages 172-181
Journal: Carbohydrate Polymers - Volume 201, 1 December 2018, Pages 172-181
نویسندگان
Benjamin R. Riegger, Regina Kowalski, Luise Hilfert, Günter E.M. Tovar, Monika Bach,