Bioinspired carbon quantum dots for sensitive fluorescent detection of vitamin B12 in cell system

The biomimetic carbon quantum dots were first synthesized as efficient fluorescence probe for vitamin B12 in cell system. The fluorescence of BCQDs is obviously quenched only by vitamin B12 even at fairly low concentrations. The BCQDs, further, showed its excellent biocompatibility and cell imaging. This result meant that a high selective and sensitive fluorescence probe had been built for the detection of trace vitamin B12.202