کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8959545 1646324 2018 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bifurcation solutions of a free boundary problem modeling tumor growth with angiogenesis
ترجمه فارسی عنوان
راه حل های دوختگی یک مشکل مرزی رایگان مدل سازی رشد تومور با آنژیوژنز
کلمات کلیدی
رشد تومور، مشکل مرزی آزاد راه حل دوگانه وجود داشتن،
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات آنالیز ریاضی
چکیده انگلیسی
In this paper we study bifurcation solutions from the unique radial solution of a free boundary problem modeling stationary state of tumors with angiogenesis. This model comprises two elliptic equations describing the distribution of the nutrient concentration σ=σ(x) and the inner pressure p=p(x). Unlike similar tumor models that have been intensively studied in the literature where Dirichlet boundary condition for σ is imposed, in this model the boundary condition for σ is a Robin boundary condition. Existence and uniqueness of a radial solution of this model have been successfully proved in a recently published paper [20]. In this paper we study existence of nonradial solutions by using the bifurcation method. Let {γk}k=2∞ be the sequence of eigenvalues of the linearized problem. We prove that there exists a positive integer k⁎⩾2 such that in the two dimension case for any k⩾k⁎, γk is a bifurcation point, and in the three dimension case for any even k⩾k⁎, γk is also a bifurcation point.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Mathematical Analysis and Applications - Volume 468, Issue 1, 1 December 2018, Pages 391-405
نویسندگان
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