Polymorphisms in the interferon-γ gene at position +874 in patients with chronic hepatitis C treated with high-dose interferon-α and ribavirin

In conclusion, we found that with high SVR rates after combination therapy with high-dose IFN-α and ribavirin, HCV genotypes and pretreatment serum HCV RNA levels, but not inheritance of the IFN-γ polymorphism at the position +847, were predictors for SVR.