کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9016422 1128095 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimized voxel-based morphometry of gray matter volume in first-episode, antipsychotic-naïve schizophrenia
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Optimized voxel-based morphometry of gray matter volume in first-episode, antipsychotic-naïve schizophrenia
چکیده انگلیسی
This study examined gray matter (GM) volume abnormalities in first-episode, antipsychotic-naïve Indian schizophrenia patients. Magnetic resonance images of 18 schizophrenia patients and 18 matched healthy comparison subjects were analyzed by optimized voxel-based morphometry. Schizophrenia patients had significantly smaller global GM and greater global CSF volumes and smaller regional GM volume in superior frontal, inferior frontal, cingulate, post-central, superior temporal and parahippocampal gyri, inferior parietal lobule, insula, caudate nuclei, thalamus and cerebellum. Findings suggest limbic, heteromodal cortical, striatal, thalamic and cerebellar abnormalities in schizophrenia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 29, Issue 4, May 2005, Pages 587-591
نویسندگان
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