کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9107676 | 1153947 | 2005 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cell rearrangements during development of the somite and its derivatives
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cell rearrangements during development of the somite and its derivatives Cell rearrangements during development of the somite and its derivatives](/preview/png/9107676.png)
چکیده انگلیسی
The generation of somites, and the subsequent formation of their major derivatives, muscle-, cartilage-, dermis- and tendon-cell lineages, is tightly orchestrated and, to different extents, these are also mutually supporting processes. They involve complex and timely reorganizations of the paraxial mesoderm, such as multiple phases of epithelial-mesenchymal rearrangements and vice-versa, cellular movements and migrations, and modifications of both cell shape and cell cycle properties. These morphogenetic changes are triggered by local environmental signals and are tightly associated to a genetic program imparting cell-specific fates. Elucidating these signals and their downstream effectors, in addition to determining the state of specification of responsive cell subsets and that of single progenitors in the various domains, is only beginning.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 15, Issue 4, August 2005, Pages 371-380
Journal: Current Opinion in Genetics & Development - Volume 15, Issue 4, August 2005, Pages 371-380
نویسندگان
Chaya Kalcheim, Raz Ben-Yair,