کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9107788 | 1153952 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation?
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation? TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation?](/preview/png/9107788.png)
چکیده انگلیسی
Understanding the relationship between growth and proliferation in multicellular organisms requires identification of the key regulators of growth control, and an understanding of how they regulate growth and how growth is linked to cell proliferation. Recent progress in understanding the mechanisms of growth control indicates that the tuberous sclerosis complex tumour-suppressor TSC1-2 serves as a point of integration between growth-stimulatory and growth-suppressive signalling upstream of a small GTPase, Rheb. However, Rheb-induced growth might not explain the additional effects of TSC1-2 upon cell proliferation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 15, Issue 1, February 2005, Pages 69-76
Journal: Current Opinion in Genetics & Development - Volume 15, Issue 1, February 2005, Pages 69-76
نویسندگان
Greg M Findlay, Laura S Harrington, Richard F Lamb,