Association of Heparin-Dependent Antibodies and Adverse Outcomes in Hemodialysis Patients: A Population-Based Study

Despite repetitive heparin exposure, the prevalence of HIT in patients undergoing maintenance hemodialysis is no greater than that anticipated for other patient populations. However, to our knowledge, this is the first study to show an association between elevated PF4-heparin antibodies and increased mortality rates in hemodialysis patients.