کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9191941 1186607 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of thyroid hormone treatment on the respiratory activity of cerebral mitochondria from hypothyroid rats. A critical re-assessment
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Influence of thyroid hormone treatment on the respiratory activity of cerebral mitochondria from hypothyroid rats. A critical re-assessment
چکیده انگلیسی
Effects of treatment with thyroid hormones l-3,5,3′-tri-iodothyronine (T3) and l-thyroxine (T4) on oxidative energy metabolism in cerebral mitochondria from hypothyroid adult rats were examined. It was observed that T3 and T4 stimulated respiratory activity in a substrate-specific and dose-dependent manner. The results also suggest that the synthesis of cytochrome aa3 and of cytochrome c may be dependent on both T3 as well as T4 whereas higher concentrations than normal of T3 and T4 may have a catabolic influence on cytochrome b content.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Neurology - Volume 195, Issue 2, October 2005, Pages 416-422
نویسندگان
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