کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9203687 | 1190482 | 2005 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antioxidant nutrient intake and supplements as potential moderators of cognitive decline and cardiovascular disease in obstructive sleep apnea
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کلمات کلیدی
Antioxidants - آنتی اکسیدانobstructive sleep apnea - آپنه خواب انسدادیalpha-lipoic acid - اسید آلفا لیپوئیکcardiovascular disease - بیماری قلب و عروقیOxidative stress - تنش اکسیداتیوCytokines - سیتوکین هاNutrient intake - مصرف غذاCognitive deficits - نقص شناختیhomocysteine - هوموسیستئینCoenzyme Q10 - کوآنزیم Q10
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
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چکیده انگلیسی
Cognitive deficits and cardiovascular disease (CVD) are comorbid conditions frequently associated with obstructive sleep apnea (OSA). Oxygen free radical release and its differential regulation of cytokine synthesis and immune modulation resulting from OSA-related hypoxic events have been hypothesized as the underlying mechanism(s) for the cognitive deficits and CVD in OSA. A number of studies have suggested that increased levels of oxidative stress and/or antioxidant deficiencies may also be risk factors in cognitive decline and CVD. The influence of antioxidant nutrients and supplements, such as Vitamins B6, B12, C, E, folic acid, alpha-lipoic acid and Coenzyme Q10 on cognitive decline and CVD have been investigated. The influence of antioxidant nutrients or supplements on OSA remains to be investigated. Even if dietary or supplemental antioxidants do not prove to be effective therapies for OSA, dietary assessment and prescription to increase dietary intake of neuro- and cardio-protective nutrients may make it possible to reduce some of the cognitive and cardiovascular sequelae associated with OSA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sleep Medicine Reviews - Volume 9, Issue 6, December 2005, Pages 459-476
Journal: Sleep Medicine Reviews - Volume 9, Issue 6, December 2005, Pages 459-476
نویسندگان
Carol M. Baldwin, Richard R. Bootzin, Dawn C. Schwenke, Stuart F. Quan,