کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9220589 1200329 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Brain structures and receptors involved in alertness
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Brain structures and receptors involved in alertness
چکیده انگلیسی
We hypothesize that the dorsomedial hypothalamic nucleus (DMH) modulates the circadian rhythm of sleep and waking via projections to the LC. We propose a SCN-DMH-LC signalling pathway that may influence the activity of the LC and thereby a variety of central nervous system functions related to noradrenergic innervations, including alertness, vigilance, attention, learning and memory. The influence of sleep drive on the LC system may be important for our understanding of the deleterious effects of sleep loss on performance, and presents a logical target for developing new treatments to counteract impairments in alertness and performance due to poor quality sleep.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sleep Medicine - Volume 6, Supplement 1, 2005, Pages S3-S7
نویسندگان
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