کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9266189 1217272 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Salmonella flagellin, a microbial target of the innate and adaptive immune system
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Salmonella flagellin, a microbial target of the innate and adaptive immune system
چکیده انگلیسی
Bacterial flagellins are important components of the motility apparatus used by many microbial pathogens. These proteins are also targets of the innate and adaptive immune response of the host during infection and autoimmune disease. Flagellin interacts with TLR-5 and leads to the generation of a pro-inflammatory response and activation of host dendritic cells in vivo. Furthermore, flagellin is recognized by antibody and CD4 T cells responses during Salmonella infection. Here, we review recent developments in the understanding of flagellin interactions with the host immune system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology Letters - Volume 101, Issue 2, 15 November 2005, Pages 117-122
نویسندگان
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