کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9268495 1219119 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chronic hepatitis B: recommendations for therapy based on the natural history of disease in Australian patients
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Chronic hepatitis B: recommendations for therapy based on the natural history of disease in Australian patients
چکیده انگلیسی
Perinatal or early childhood transmission is predominant mode of infection in Australia. Two thirds of this cohort had active replication and were at increased risk of developing cirrhosis and/or hepatoma. Advanced disease was associated with age and ethnicity. HBeAg negative CHB accounts for almost half of all those with active viral replication. This parallels the rise in this form of CHB in Asia and the Mediterranean basin. Screening should be offered to people born in, or with parents born in areas of high endemnicity. To detect the development of active disease, patients with positive HBsAg but normal ALT should have liver function tests done 6 monthly and those with elevated ALT should be referred for consideration of therapy, irrespective of HBeAg status.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Virology - Volume 32, Issue 2, February 2005, Pages 122-127
نویسندگان
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