کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9273520 1221081 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reevaluating current models of thymic involution
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Reevaluating current models of thymic involution
چکیده انگلیسی
It is generally accepted that thymic involution commences, or at least accelerates, at puberty due to increases in sex steroid and declines in growth hormone production. As a result of these hormonal changes, the development of the most immature intrathymic progenitors is blocked. However, aspects of this model are now being questioned. The present chapter re-evaluates a number of findings on which traditional models of thymic involution are based and reviews new data that, taken together, indicate a need to revise current views of thymic involution.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Immunology - Volume 17, Issue 5, October 2005, Pages 356-361
نویسندگان
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