کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9289494 1228317 2005 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genetic characterization of L-Zagreb mumps vaccine strain
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ویروس شناسی
پیش نمایش صفحه اول مقاله
Genetic characterization of L-Zagreb mumps vaccine strain
چکیده انگلیسی
L-Zagreb nucleotide and deduced protein sequences were compared with other mumps virus sequences obtained from the GenBank. Emphasis was put on functionally important protein regions and known antigenic epitopes. The extensive comparisons of nucleotide and deduced protein sequences between L-Zagreb vaccine strain and other previously determined mumps virus sequences have shown that while the functional regions of HN, V, and L proteins are well conserved among various mumps strains, there can be a substantial amino acid difference in antigenic epitopes of all proteins and in functional regions of F protein. No molecular pattern was identified that can be used as a distinction marker between virulent and attenuated strains.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virus Research - Volume 109, Issue 1, April 2005, Pages 95-105
نویسندگان
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