Integración de teorías del envejecimiento (parte I)

Currently, the cellular disorganization of ageing is generally accepted to be linked to the oxidative stress caused by free radicals and other reactive oxygen species (ROS), in agreement with the theories published independently by Harman and Gerschman. Also widely accepted is the key role of the mitochondrial genes of differentiated cells as the main target of ROS attack, according to the oxygen stress/mitochondrial damage theory proposed by the present author.