کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9646478 548029 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A family-based study of the association between the G72/G30 genes and schizophrenia in the Chinese population
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
A family-based study of the association between the G72/G30 genes and schizophrenia in the Chinese population
چکیده انگلیسی
Studies have shown a strong positive association between schizophrenia and G72/G30, demonstrated by both individual markers and haplotypes. A further functional study also supports the role of G72 in the etiology of schizophrenia. In this study, we have replicated these results of transmission/disequilibrium testing (TDT) and haplotype analysis in the Han Chinese population, showing P values of 0.0018 and 0.00007 for individual markers and haplotypes, respectively. Hence, our data supports the hypothesis that G72/G30 are important candidate genes for explaining schizophrenia in the Han Chinese population.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Schizophrenia Research - Volume 73, Issues 2–3, 1 March 2005, Pages 257-261
نویسندگان
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