کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9676098 1454114 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microstructure and gelation behavior of hydroxyapatite-based nanocomposite sol containing chemically modified silk fibroin
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Microstructure and gelation behavior of hydroxyapatite-based nanocomposite sol containing chemically modified silk fibroin
چکیده انگلیسی
Nanocomposite sol comprised of hydroxyapatite (HA) and silk fibroin (SF) was synthesized via a wet-mechanochemical route. SF particles were chemically modified using an alkali solution attempting to disentangle their surface fibrils so as to enhance the effective contact between the mineral and the organic particles. With the alkali pretreated SF involved, Vickers microhardness of the composite increases by 57% and a more enhanced three-dimensional porous network with a homogenous particle form and a uniform pore size distribution is formed through the intimate crosslinkage between HA clusters and SF fibrils. In addition, the alkali pretreatment of SF not only increased the viscosity and the rigidity of the composite sol, but also promotes its gelation process, which is favorable for healing bone defects by an injection technique.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Volume 254, Issues 1–3, 10 March 2005, Pages 159-164
نویسندگان
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