Analytical applications of peroxyoxalate chemiluminescence

Coupled with high-performance liquid chromatography (HPLC), flow injection analysis or capillary electrophoresis, peroxyoxalate chemiluminescence (POCL) reaction was proved to be a useful, selective and sensitive detection system for the analytes including hydrogen peroxide, native fluorescent compounds and fluorescent derivatized compounds. Its application to quantitation of polycyclic aromatic hydrocarbons (PAHs) and catecholamines has afforded tremendous benefit in the field of environmental and clinical sciences. This review covers the reports on the analytical application of POCL reaction from the late 1970s to the most recent.