کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9743623 1491195 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Flow-injection chemiluminescence determination of meloxicam by oxidation with N-bromosuccinimide
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Flow-injection chemiluminescence determination of meloxicam by oxidation with N-bromosuccinimide
چکیده انگلیسی
A rapid and sensitive flow-injection chemiluminescence method is described for the determination of meloxicam based on its reaction with N-bromosuccinimide (NBS) in alkaline medium. Under the optimum conditions, the proposed method allows the measurement of meloxicam over the range of 2.2 × 10−7 to 2.8 × 10−5 mol/l with a detection limit of 7.7 × 10−8 mol/l. The relative standard deviation for 11 parallel measurements of 2.8 × 10−6 mol/l meloxicam is 2.14%. The method has been applied satisfactorily to the determination of meloxicam in pharmaceutical preparations. The results agree well with those obtained by spectrophotometry. The mechanism of the chemiluminescence reaction is briefly explained with spectroscopic evidence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 541, Issues 1–2, 13 June 2005, Pages 185-190
نویسندگان
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