کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9743839 | 1491200 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecularly imprinted polymer thin films on quartz crystal microbalance using a surface bound photo-radical initiator
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The present work aims to study preparation of thin MIP films on a gold-coated QCM resonator in a well-controlled and reproducible manner. A surface-bound photo-radical initiator was used to furnish an imprinting polymerization in a dilute solution of template, functional monomer and crosslinker. Prior to polymerization, the photo-initiator was covalently coupled to a self-assembled monolayer of carboxyl terminated alkanethiol on a gold surface. With this approach we were able to control the thickness of the MIP film to be below 50Â nm, where the selective recognition of target analytes can be easily detected by the underlying quartz crystal resonator. When used in a flow injection analysis system, the assembled QCM sensor generated a large frequency change (>30Â Hz) upon encountering a small amount of analyte (0.19Â mM). The sensor had a very short response time (<1Â min), and displayed certain chiral selectivity towards the original template, (S)-propranolol at a concentration higher than 0.38Â mM in aqueous solution.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 536, Issues 1â2, 22 April 2005, Pages 191-196
Journal: Analytica Chimica Acta - Volume 536, Issues 1â2, 22 April 2005, Pages 191-196
نویسندگان
Theeraphon Piacham, Ã
sa Josell, Hans Arwin, Virapong Prachayasittikul, Lei Ye,