کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9743957 | 1491203 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Determination of clenbuterol, ractopamine and zilpaterol in liver and urine by liquid chromatography tandem mass spectrometry
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Beta-agonists have been misused as growth promoting agents in meat producing animals over 20 years. Clenbuterol (CLB) was the main beta-agonist substance used illegally for this purpose. But other beta-agonist substances have been developed to be used for zootechnical purposes, such as ractopamine (RCT), licensed for this application in the United States and currently zilpaterol (ZIL), licensed in South Africa and Mexico. However, these compounds are banned in the European Union (EU) Council Directive 96/22/EC. An analytical method able to identify these three beta-agonists by liquid chromatography tandem mass spectrometry (LC-MS-MS), after clean-up with mixed-mode SPE Bond Elut Certify cartridges (6 mL, 300 mg) was developed and validated according to the Commission Decision 2002/657/EC. Decision limit (CCα) ranged from 40 to 110 pg mLâ1 and from 80 to 150 pg gâ1 (ppt) for urine and liver, respectively. Detection capability (CCβ) ranged from 180 to 270 pg mLâ1 and 270 to 520 pg gâ1 (ppt) for urine and liver respectively. This method appeared suitable for the control of these beta-agonists residues in liver and urine.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 529, Issues 1â2, 24 January 2005, Pages 199-205
Journal: Analytica Chimica Acta - Volume 529, Issues 1â2, 24 January 2005, Pages 199-205
نویسندگان
José Blanca, Patricia Muñoz, Miguel Morgado, Nely Méndez, Angela Aranda, Thea Reuvers, Henny Hooghuis,