Oxidative stress on mitochondrial antioxidant defense system in the aging process: Role of dl-α-lipoic acid and l-carnitine

Co-supplementation of lipoic acid with carnitine has a beneficial effect in reversing the age-related abnormalities seen in aging. This effect was associated with the decrease in free radical production and rise in antioxidant levels by carnitine and lipoic acid, thereby lowering oxidative stress.