Keywords: Preeclampsia; 20-HETE; Placental ischemia; RUPP rat;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: ARA; arachidonic acid; COX; cyclooxygenase; CYP 450; cytochrome P450; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; FLIPR; fluorescent imaging plate reader; 22-HDoHE; 22-hydroxydocosahexaenoic acid; 20-HEPE; 20-hydroxyeicosapentaenoic acid; 20-HE
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; ACE; angiotensin converting enzyme; ACEI; angiotensin converting enzyme inhibitor; Agt; angiotensinogen; Agt â/â; Â Agt whole body knock-out mouse model; AMPK; AMP-activated protein kinase; Ang II; angiotensin
Keywords: 2-AG; 2-arachidonyl glycerol; 20-HETE; 20-hydroxy-5,8,11,14-eicosatetraenoic acid; 9-HODE; 9-hydroxy-octadecadienoic; 13-HODE; 13-hydroxy-octadecadienoic; AA; arachidonic acid; AEA; anandamide; ALA; α-linolenic acid; BMI; body mass index (kg/m2); cAMP; c
Keywords: P450; Arachidonic acid; Epoxygenase; 20-HETE; EET; Hypertension;
Keywords: Arachidonic acid; Portal hypertension; Liver cirrhosis; Prostaglandins; Cyclooxygenase; Leukotrienes; Lipoxygenase; EET; 20-HETE; Cytochrome P450; Epoxygenase; Monooxygenase
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; Ang-II; angiotensin II; AP-1; activator protein 1; ARIC; Atherosclerosis Risk in Communities; ATF-6; activating transcription factor-6; CAC; coronary artery calcification; CARDIA; Coronary Artery Risk Development
The contribution of TRPV1 channel to 20-HETE-Aggravated ischemic neuronal injury
Keywords: 20-HETE; TRPV1; Oxygen-glucose deprivation; Hypoxic-ischemic injury; Neonatal;
Arachidonic acid metabolites of CYP4A and CYP4F are altered in women with preeclampsia
Keywords: Preeclampsia; Pregnancy; Hypertension; 20-HETE;
Identification of novel CYP4F2 genetic variants exhibiting decreased catalytic activity in the conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE)
Keywords: CYP4F2; Arachidonic acid; 20-HETE; Genetic polymorphism;
Regulation of blood pressure is influenced by gender: A study in obese Zucker rats
Keywords: Hypertension; Obesity; Renin-angiotensin system; Endothelin; 20-HETE;
Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation
Keywords: 20-HETE; MMP12; Elastin; Macrocirculation; Arterial compliance; Systolic hypertension;
Conflicting roles of 20-HETE in hypertension and renal end organ damage
Keywords: Cytochrome P450; 20-HETE; Hypertension; Hypertensive nephropathy; Vascular function; Sodium transport; Genetic polymorphisms;
Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites
Keywords: CYP4A11; Reaction phenotyping; HET0016; Plumbagin; Lauric acid metabolism; HLM; human liver microsomes; CYP; cytochrome P450; 20-HETE; 20-hydroxyeicosatetraenoic acids; LC-MS/MS; liquid chromatography-tandem mass spectrometry; IC50; the half maximal inh
The G protein-coupled receptors deorphanization landscape
Keywords: GPCRs; G protein-coupled receptors; GRK; GPCR kinase; IUPHAR; International Union of Basic and Clinical Pharmacology; BPS; British Pharmacological Society; CTR; Calcitonin receptor; CLR; CT Receptor-like; RAMP; Receptor Activity-Modifying Proteins; β2AR;
Shexiang Baoxin pills promotes angiogenesis in myocardial infarction rats via up-regulation of 20-HETE-mediated endothelial progenitor cells mobilization
Keywords: Shexiang Baoxin pills; 20-HETE; Endothelial progenitor cells; Vascular endothelial growth factor; Angiogenesis; Myocardial infarction;
Meloxicam fails to augment the reno-protective effects of soluble epoxide hydrolase inhibition in streptozotocin-induced diabetic rats via increased 20-HETE levels
Keywords: Meloxicam; t-AUCB; Renal injury; 20-HETE; Streptozotocin; Sprague dawley rats;
20-HETE contributes to ischemia-induced angiogenesis
Keywords: AA; arachidonic acid; 20-HETE; 20-hydroxyeicosatetraenoic acid; EC; endothelial cells; HMVEC; human microvascular endothelial cells; VEGF; vascular endothelial growth factor; VEGFR2; vascular endothelial growth factor receptor 2; HIF-1α; hypoxia-inducibl
Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females
Keywords: Female; Obesity; Inflammation; OX-HDL; 20-HETE; Isoprostane; Adiponectin; Angiotensin ll
The role of 20-HETE in cardiovascular diseases and its risk factors
Keywords: Cardiovascular disease (CVD); 20-HETE; Obesity; Diabetes;
Expression of CYP 4A Ï-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; CYP 4A enzyme; cytochrome P450 4A Ï-hydroxylase; EETs; epoxyeicosatrienoic acids; AA; arachidonic acid; HET0016; ((N-hydroxy-Nâ²-(4-butyl-2-methylphenyl)formamidine; CBF; cerebral blood flow; LC-ESI-MS; Liqu
Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid ω-hydroxylation
Keywords: Cytochrome P450; CYP4A11; Genetic polymorphisms; Hypertension; Arachidonic acid; 20-HETE
Transient postnatal fluoxetine decreases brain concentrations of 20-HETE and 15-epi-LXA4, arachidonic acid metabolites in adult mice
Keywords: Fluoxetine; Arachidonic; 5-HT; Brain; 20-HETE; 15-epi-LXA4
CommentaryRoles of human UDP-glucuronosyltransferases in clearance and homeostasis of endogenous substrates, and functional implications
Keywords: UDP-glucuronosyltransferase; Bilirubin; Serotonin; 20-HETE; Vitamins A and D; AhR; aryl hydrocarbon receptor; CAR; constitutive androstane receptor; HETE; hydroxyeicosatetraenoic acid; LTB4; leucotriene B4; PPAR; peroxisome proliferator-activated receptor
Androgen-induced hypertension in angiotensinogen deficient mice: Role of 20-HETE and EETS
Keywords: 20-HETE; Angiotensinogen; Androgen; ACE; Hypertension
Original Research ArticleIntakes of omega-3 polyunsaturated fatty acids and blood pressure change over time: Possible interaction with genes involved in 20-HETE and EETs metabolism
Keywords: Population genetics; Omega-3 fatty acids; CYP4F2; Eicosanoids; EET; 20-HETE;
Vascular actions of 20-HETE
Keywords: 20-HETE; Renin-angiotensin system; Vascular remodeling; Vascular dysfunction; Vascular inflammation; Angiogenesis;
Human fetal ventricular cardiomyocyte, RL-14 cell line, is a promising model to study drug metabolizing enzymes and their associated arachidonic acid metabolites
Keywords: RL-14 cells; Cytochrome P450; Epoxyeicosatrienoic acids; EETs; Hydroxyeicosatetraenoic acid; 20-HETE;
5,6-δ-DHTL, a stable metabolite of arachidonic acid, is a potential substrate for paraoxonase 1
Keywords: PON1; paraoxonase 1; 5,6-EET; 5,6-epoxyeicosatrienoic acid; 5,6-δ-DHTL; 5,6-Dihydroxylactone; 20-HETE; 20 hydroxyeicosatrienoic acid; DHETs; dihydroxyeicosatrenoic acids; EDHFs; endothelium-derived hyperpolarizing factors; sEH; soluble epoxide hydrolase;
Redox modulation of adipocyte differentiation: hypothesis of “Redox Chain” and novel insights into intervention of adipogenesis and obesity
Keywords: 6PGD; 6-phosphogluconate dehydrogenase; 20-HETE; 20-hydroxyeicosatetraenoic acid; AA; arachidonic acid; ADP; adenosine diphosphate; ADSCs; adipose-derived stem cells; aP2; fatty-acid binding protein; AREs; antioxidant response elements; ATP; adenosine tri
Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion
Keywords: ISL; isoliquiritigenin; AA; arachidonic acid; COX; cyclooxygenase; LOX; lipoxygenase; CYP; cytochrome P450; PGE2; prostaglandin E2; LTB4; leukotriene B4; 20-HETE; 20-hydroxyeicosatetraenoic acid; EP; prostaglandin receptor; FLAP; 5-lipoxygenase activating
Nox4 and diabetic nephropathy: With a friend like this, who needs enemies?
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; AA; arachidonic acid; AGE; advanced glycation end-product; Akt/PKB; Akt/protein kinase B; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; AOPP; advanced oxidation protein product; AT1; angiotensin II t
Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91phox to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock
Keywords: 20-HEDE; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid; AA; arachidonic acid; 20-HETE; 20-hydroxyeicosatetraenoic acid; 5,14-HEDGE; N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine; 1,3-PBIT; phenylene-1,3-bis(ethane-2-isothiourea) dihydrobromide; cDNA; compleme
Endogenously produced 20-HETE modulates myogenic and TGF response in microperfused afferent arterioles
Keywords: 20-HETE; Myogenic response; Tubuloglomerular feedback; Afferent arteriole
20-HETE in neovascularization
Keywords: Neovascularization; Arachidonic acid metabolism; 20-HETE; Endothelial cells; Endothelial progenitor cells; Signaling
The functional variant V433M of the CYP4F2 and the metabolic syndrome in Swedes
Keywords: Cytochrome P450; 20-HETE; Genetics; Metabolic syndrome; CYP4F2; Triglycerides
Pulmonary, gastrointestinal and urogenital pharmacologyInhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine
Keywords: Dopamine; 20-HETE; CYP4A; Sodium excretion;
Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; BPAEC; Bovine pulmonary artery endothelial cell; DCF; Dichlorofluorescein; DHE; Dihydroethidium; DMEM; Dulbecco's modified essential media; EC; Endothelial cell; FITC; Fluorescein isothiocyanate; LDL; Low density
Inhibition of 20-HETE attenuates diabetes-induced decreases in retinal hemodynamics
Keywords: diabetic retinopathy; blood flow; 20-HETE
The role of 20-HETE in androgen-mediated hypertension
Keywords: Androgen; DHT; Hypertension; 20-HETE; CYP4A/F; ACE; IKK; Endothelial dysfunction; Vascular reactivity;
Increased oxidative stress, the renin-angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice
Keywords: Androgens; Angiotensin II; 20-HETE; Hypertension; Oxidative stress; Kidney; Kidney androgen-regulated protein; Sympathetic system; Free radicals;
Study on the association between environmental cadmium exposure, cytochrome P450-mediated 20-HETE, heme-oxygenase-1 polymorphism and hypertension in Thai population residing in a malaria endemic areas with cadmium pollution
Keywords: Cadmium; Hypertension; 20-HETE; Heme oxygenase-1; Genetic polymorphism; Renal biomarkers
CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension
Keywords: Renovascular hypertension; 20-HETE; Cytochrome P450 Ï-hydroxylase; Oxygen; Cremaster muscle;
Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury
Keywords: 20-HETE; acute kidney injury; acute renal failure; HET0016; ischemia-reperfusion
CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb
Keywords: Cl transport; cyclooxygenase; CYP-ω-hydroxylation; 20-HETE
Calcium-independent phospholipase A2 participates in KCl-induced calcium sensitization of vascular smooth muscle
Keywords: Vascular smooth muscle; Rabbit artery; Contraction; K+-depolarization; Ca2+ signaling; Fura-2; Signal transduction; Ca2+ sensitization; Rho-kinase; PLA2; BEL; ETYA; NDGA; HET0016; H-1152; HA-1077; Y-27632; 20-HETE; Pyrrolidine-1; GF-109203X; PKC pseudo-su
Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats
Keywords: 20-HETE; TS-011; Ischemic stroke; Neurological outcome; Functional outcome; Brain infarction
A reduction in alcohol consumption is associated with reduced plasma F2-isoprostanes and urinary 20-HETE excretion in men
Keywords: Free radicals; Alcohol; 20-HETE; Isoprostanes; Blood pressure;
Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats
Keywords: Diabetes; Erectile dysfunction; Epoxyeicosatrienoic acid; 20-HETE
20-Carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors α and γ
Keywords: Cytochrome P450; Ï-Oxidation; Arachidonic acid; 20-HETE; Nuclear receptors;