Keywords: Mouse; Aggression; Wound; Welfare; 3Rs; Husbandry;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Household waste; 3Rs; Sustainable consumption; Green practices;
Keywords: Acute inhalation studies; 3Rs; Evident toxicity; Fixed concentration procedure (FCP); Refinement; Regulatory toxicology; TG403; TG436; TG433; ATC; acute toxic class; CI; confidence interval; FCP; fixed concentration procedure; GHS; globally harmonised sys
Keywords: Ontology; Developmental neurotoxicity; Validation; 3Rs; Brain development;
Keywords: Microsampling; Mouse; Fetus; Embryofetal development; Fetal weight; 3Rs;
Keywords: Welfare; Laboratory-housed dog; 3Rs; Home pen design; Husbandry; Facility design; Housing; Enrichment; Strain;
Keywords: Exposure; Risk assessment; 3Rs; (Toxico)kinetics; PBPK; Regulatory;
Keywords: AHT; Animal Health Trust; EI; equine influenza; EIV; equine influenza virus; ESP; equine surveillance panel; FC1 or FC2 respectively; Florida clade 1 or clade 2; 3Rs; replacement reduction and refinement; Equine influenza; Horse; Nebulisation; Pathogenici
Keywords: Biologic; Ocular; Ophthalmic; Rabbit; Anti-drug antibody; Inflammation; 3Rs;
Keywords: RE; Renewable energy; 3Rs; Reduce, Recover, Recycle; ABC; Action plan for a Beautiful and Clean Malaysia; Biogen; Biomass generation and demonstration project; CDM; Clean Development Mechanism; CER; Certified emission reduction; CETDEM; Center for Environ
Keywords: ENPs; Engineered Nanoparticles; TiO2; titanium dioxide; Au; gold; CuO; copper oxide; ZnO; zinc oxide; MNM; manufactured nanomaterials; GHS; globally harmonized system; 3Rs; three Rs principles; QSAR; quantitative structure-activity relationship; DLS; dy
Keywords: Acute systemic toxicity; Alternatives; LD50; Oral; Dermal; Inhalation; 3Rs; In vitro; In silico;
Keywords: Air-liquid interface aerosol exposure; Metabolomics; 3Rs; 21st century toxicology; Tobacco heating system 2.2; Gingiva;
Keywords: Skin; Wound healing; In vitro; Migration; 3Rs;
Keywords: [3H]DG; [3H]-2-deoxy-d-glucose; [18F]FDG-PET; [18F]-fluorodeoxyglucose-positron emission tomography; [3H]GABA; tritiated γ-aminobutyric acid; 2-AG; 2-arachidonoyl-glycerol; 3Rs; replacement refinement and reduction of animals in research; α,βHD6/12; α
Keywords: 3Rs; Replacement, Refinement And Reduction; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care International; ARRIVE; Animal Research: Reporting of In Vivo Experiments; AWERB; Animal Welfare and Ethical Review Body; CCTV; close
Keywords: Rabies vaccine control; ELISA method; Antigenically active glycoprotein; 3Rs; In vitro alternative method;
Keywords: Acute inhalation studies; 3Rs; Evident toxicity; Fixed concentration procedure (FCP); Refinement; Regulatory toxicology; TG4303; TG436; TG433; fixed concentration procedure; FCP;
Keywords: 3Rs; reduce, refine, replace; A; apical; ABC; ATP-binding cassette; B; basal; BCF; bioconcentration factor; BTA; bi-directional transport assay; CETA; concentration equilibrated transport assay; Ci; Curie; Dpm; disintegrations per minute; Kow; octanol-w
Keywords: In vitro; In vivo; Animal model; Species selection; Disease model; 3Rs; Predictive value; Preclinical safety assessment; Regulatory guidance; Guidelines; ICH; Critical Path Initiative; Innovative Medicines Initiative; Induced pluripotent stem cells;
Keywords: Dog; Dosing; Oral; Gavage methods; Toxicology; Refinement; 3Rs; Welfare;
Keywords: Landfill reclamation; Biodiversity preservation; Global warming mitigation; Landfill mining; Ex-post monitoring; Public safety; 3Rs; waste reduction, recuse and recycling; 5Rs; waste reduction, recuse, recycling, energy recovery and land reclamation; CBD;
Keywords: Bioconcentration; BCF; Fish; Chemicals; 3Rs;
Keywords: Fish; Acute toxicity; Threshold approach; Ecotoxicity; 3Rs;
Keywords: Vaccines; Viral safety; In vitro; In vivo; Adventitious agents; 3Rs;
Keywords: 3Rs; Repeated dose; Sub-chronic; REACH; Chemicals legislation; Alternatives; Sub-acute;
Keywords: Recovery; Reversibility; 3Rs; Reduction; Non-clinical; Repeat-dose studies; Regulatory toxicology; Rodent; Primate; Dog;
Keywords: Bioconcentration; BCF; Fish; Plant protection products; 3Rs;
Keywords: 3Rs; replacement, reduction, refinement; NC3Rs; National centre for the replacement, refinement and reduction of animals in research; BWL; body weight loss; MTD; maximum tolerated dose; NHPs; non-human primates; 3Rs; Body weight loss (BWL); Maximum tolera
Keywords: Drug development; Translational research; Inflammatory bowel disease; Colitis; Biomarkers; Endpoints; AA; alternative approaches; CD; Crohn's disease; 3Rs; Replacement, Reduction, Refinement; DHODH; dihydroorotate dehydrogenase; DNBS; dinitrobenzene sulph
Keywords: 3Rs; replacement, refinement and reduction of animals in research; ACSA; Agricultural Chemicals Safety Assessment; ADA; anti-drug antibody; CNS; central nervous system; DBS; dried blood spot; DART; developmental and reproductive toxicity; DRF; dose range
Keywords: Cell lines; 3Rs; QSAR; Read-across; Exposure-based waiving; Fish embryo test; Acute toxicity; Chronic toxicity; Endocrine disruption; Bioconcentration;
Antinociceptive activity of ethanolic extract of Azadirachta indica A. Juss (Neem, Meliaceae) fruit through opioid, glutamatergic and acid-sensitive ion pathways in adult zebrafish (Danio rerio)
Keywords: EtFrNeem; A. indica fruit ethanolic extract; FT-IR; fourier transform infrared spectroscopy; NMDA; N-methyl-D-aspartate (glutamatergic receptor); ASICs; acid-sensing ion channels; eROS; extracellular reactive oxygen species; 3Rs; ethical principle: reduce
PBT assessment under REACH: Screening for low aquatic bioaccumulation with QSAR classifications based on physicochemical properties to replace BCF in vivo testing on fish
Keywords: BCF waiving scheme; 3Rs; Octanol/water partition coefficient (log Kow); (Bio)degradability; Consensus modelling; Structural similarity with nonB/B/vB substances;
Assessing the impact of benzo[a]pyrene with the in vitro fish gut model: An integrated approach for eco-genotoxicological studies
Keywords: NF; naphthoflavone; 3Rs; Replace, Reduce, Refine; ADME; Adsorption, Distribution, Metabolism and Excretion; AHR; Aryl hydrocarbon receptor; AOP; Adverse Outcome Pathway; APH; Acid phosphatase; B[a]P; Benzo[a]pyrene; DMSO; Dimethyl sulfoxide; ECVAM; Europe
Cell cultures in drug discovery and development: The need of reliable in vitro-in vivo extrapolation for pharmacodynamics and pharmacokinetics assessment
Keywords: 3Rs; Reduction, Replacement, Refinement; PBPK; physiologically based pharmacokinetic; 2D; two-dimensional; 3D; three-dimensional; HTS; high-throughput screening; IVIVE; in vitro-in vivo extrapolation; ADME; absorption, distribution, metabolism and excreti
An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs
Keywords: Xenopus; Sperm; Cryopreservation; Stock centres; Genetically altered lines; 3Rs;
Multivariate analysis of the immune response to a vaccine as an alternative to the repetition of animal challenge studies for vaccines with demonstrated efficacy
Keywords: Rabies vaccine; RABISIN®; Immune fingerprint; Principle component analysis; 3Rs;
ReviewFish embryo toxicity test, threshold approach, and moribund as approaches to implement 3R principles to the acute fish toxicity test
Keywords: Zebrafish embryo; Animal welfare; Alternative testing; 3Rs; Threshold approach;
Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?
Keywords: 3rs; Alternative approaches; Nanotoxicology; Nanosafety; Regulatory testing; In vitro/in silico;
A protocol for training group-housed rhesus macaques (Macaca mulatta) to cooperate with husbandry and research procedures using positive reinforcement
Keywords: 3Rs; Group training; Macaque; Positive reinforcement training; Primates; Stationing;
The utility of QSARs in predicting acute fish toxicity of pesticide metabolites: A retrospective validation approach
Keywords: Pesticides; Metabolites; QSARs; Fish toxicity; 3Rs;
Development and validation of a quantitative competitive ELISA for potency testing of equine anti rabies sera with other potential use
Keywords: Competitive ELISA; Rabies immunoglobulins (ERIGs, HRIGs); Quality control; Validation; 3Rs; Batch release;
Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease
Keywords: Anandamide (AEA); β-amyloid; Cerebral glucose uptake; Cannabinoid CB2 receptor; Cyclooxygenase-2 (COX-2); Positron emission tomography (PET); 2-AG; 2-arachidonoylglycerol; 3Rs; replacement, refinement and reduction of animals in research; ABDH6/12; α/β
Basic neuroscienceOpportunities for improving animal welfare in rodent models of epilepsy and seizures
Keywords: 3Rs; Animal model; Epilepsy; Mouse; Rat; Refinement; Seizure;
GHS additivity formula: A true replacement method for acute systemic toxicity testing of agrochemical formulations
Keywords: Acute toxicity; GHS; Theory of additivity; Replacement; Global policy change; 3Rs; ANVISA; Agência Nacional de Vigilância Sanitária (Brazil); AF; Additivity formula; ATE; Acute Toxicity Estimate; EPA; Environmental Protection Agency (US); CLP; Classifi
Aligning the 3Rs with new paradigms in the safety assessment of chemicals
Keywords: 3Rs; replacement, refinement and reduction of animals in research; AOP; adverse outcome pathway; EURL-ECVAM; European Union Reference Laboratory for Alternatives to Animal Testing; ICCVAM; Interagency Coordinating Committee on the Validation of Alternativ
Impact analysis of ICH S9 on non-clinical development of anticancer drugs
Keywords: Oncology; Cancer; Drug development; International Conference for Harmonisation; ICH S9; Centralised procedure; EMA; 3Rs; Animal welfare;
Environmental monitoring of urban streams using a primary fish gill cell culture system (FIGCS)
Keywords: cyp1a1; cyp3; Metallothionein; Fish; Environmental monitoring; Cell culture; 3Rs
Developing biorobotics for veterinary research into cat movements
Keywords: 3Rs; biorobotics; cat; gait analysis; locomotion; noninvasive