دانلود مقالات ISI درباره فعال کردن عامل رونویسی 4 + ترجمه فارسی

Ethanol-induced PGE2 up-regulates Aβ production through PKA/CREB signaling pathway

Keywords: فعال کردن عامل رونویسی 4; Aβ; amyloid beta; AD; Alzheimer's disease; APP; amyloid precursor protein; BACE1; beta-site APP-cleaving enzyme 1; ROS; reactive oxygen species; ER; endoplasmic reticulum; eIF2α; eukaryotic initiation factor alpha; CHOP; C/EBP-homologous protein; PGE2;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Stress granules assembly affects detection of mRNA in living cells by the NanoFlares; an important aspect of the technology

Keywords: فعال کردن عامل رونویسی 4; ARE; AU-rich element; ATF-4; activating transcription factor 4; BRCA1; breast cancer type 1 susceptibility; CML; chronic myeloid leukemia; eIF2α; eukaryotic initiation factor subunit α; EM; emetine; ER; endoplasmic reticulum; FBS; fetal bovine serum; mR

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells

Keywords: فعال کردن عامل رونویسی 4; F6P; fructose 6-phosphate; HBP; Hexosamine Biosynthetic Pathway; GlcN6P; glucosamine-6-phosphate; GFAT; glutamine-fructose-6-phosphate amidotransferase; UDP-GlcNAc; UDP-N-acetylglucosamine; O-GlcNAc; O-GlcNAcylation; GAM; Glucosamine; VEGF; vascular endot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewThe UPR and synaptic dysfunction in neurodegeneration

Keywords: فعال کردن عامل رونویسی 4; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; Aβ; Beta-Amyloid; BiP; Binding immunoglobulin Protein; CHOP; C/EBP Homologous Protein; CREB; Cyclic AMP Response Element Binding Protein; eIF2; Eukaryotic Initiation Factor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Increase in antioxidant activity by sheep/goat whey protein through nuclear factor-like 2 (Nrf2) is cell type dependent

Keywords: فعال کردن عامل رونویسی 4; Antioxidant; C2C12; EA.hy926; Nrf2; Whey protein; AREs; antioxidant response elements; ATF4; activating transcription factor 4; CAT; catalase; CDNB; 1-chloro-2,4-dinitrobenzene; DETAPAC; diethylenetriaminepentaactic acid; DTT; dithiothreitol; EDTA; ethyle

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

miR-214 protects erythroid cells against oxidative stress by targeting ATF4 and EZH2

Keywords: فعال کردن عامل رونویسی 4; ATF-4; activating transcription factor 4; Bim; BCL2-like 11; EZH2; enhancer of zeste 2 polycomb repressive complex 2 subunit; eIF2; eukaryotic initiation factor-2; Fe-NTA; ferric nitrilotriacetate; Hri; eukaryotic translation initiation factor 2 alpha kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway

Keywords: فعال کردن عامل رونویسی 4; Aβ; amyloid-β; AD; Alzheimer's disease; ALA; α-linolenic acid; ANOVA; analyses of variance; APP; amyloid-β precursor protein; ATF4; activating transcription factor 4; BACE1; β-site APP-cleaving enzyme 1; BSA; bovine serum albumin; CAA; cerebral amy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer

Keywords: فعال کردن عامل رونویسی 4; 4E-BP-1; eukaryotic initiation factor 4E binding protein-1; ATF4; activating transcription factor 4; Bcl2; B-cell lymphoma 2; C/EBP; CAAT/enhancer binding protein; cdc-2; cyclin-dependent kinase 1 (cell division cycle protein 2); CHOP; CAAT/enhancer bindi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Adaptive preconditioning in neurological diseases - therapeutic insights from proteostatic perturbations

Keywords: فعال کردن عامل رونویسی 4; ARE; anti-oxidant response element; ASK1; apoptosis signal regulating kinase 1; ATF4; activating transcription factor 4; ATF6α; activating transcription factor 6α; BI-1; Bax-inhibitor-1; Bim; Bcl-2-interacting mediator of cell death; BiP/GRP78; binding

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal

Keywords: فعال کردن عامل رونویسی 4; Ovarian cancer; DBeQ; ML240; Salubrinal; ER stress; Unfolded protein response; CB-5083; Synergy; AAA-ATPase; ATPase associated with diverse cellular activities; BRCA1/2; breast cancer 1/2; PARP1; poly ADP-ribose polymerase-1; DBeQ; N2,N4-dibenzylquinazoli

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain

Keywords: فعال کردن عامل رونویسی 4; 4-PBA; 4-phenyl butyric acid; 6-OHDA; 6-hydroxydopamine; Aβ; amyloid beta; AD; Alzheimer's disease; ATF3; activating transcription factor 3; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BACE1; β-site APP cleaving enz

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

PERK-eIF2α-ATF4 pathway mediated by endoplasmic reticulum stress response is involved in osteodifferentiation of human periodontal ligament cells under cyclic mechanical force

Keywords: فعال کردن عامل رونویسی 4; α-MEM; alpha minimum essential medium; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BMP2; bone morphogenic protein 2; BSP; bone sialoprotein; CREB; cAMP response element binding; CMF; cyclic mechanical force; DM; diab

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression

Keywords: فعال کردن عامل رونویسی 4; Apoptosis; Bcl-2; ER stress; GCN5; Gene targeting; AFT4; activating transcription factor 4; AFT6; activating transcription factor 6; Bax; B-cell lymphoma-associated X; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra-large; CHOP; C/EBP-homologous p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in association with its effects suppressing endoplasmic reticulum stress in db/db mice

Keywords: فعال کردن عامل رونویسی 4; ER; endoplasmic reticulum; TRIB3; tribbles homolog 3; ATF-4; activating transcription factor 4; CHOP; C/EBP homologous protein; GLP-1; Glucagon-like peptide-1; Endoplasmic reticulum; Type 2 diabetes; Vildagliptin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells

Keywords: فعال کردن عامل رونویسی 4; AA; amino acid; AAR; AA response; ActD; actinomycin D; ASNS; asparagine synthetase; ATF4; activating transcription factor 4; cFOS; FBJ murine osteosarcoma viral oncogene homolog; DOX; doxycycline; eIF2; eukaryotic initiation factor 2; ERK; extracellular-s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing

Keywords: فعال کردن عامل رونویسی 4; AD; adefovir dipivoxil; AhR; aryl hydrocarbon receptor; AMIO; amiodarone; APAP; acetaminophen; ATF4; activating transcription factor 4; CAA; chloroacetaldehyde; CdCl2; cadmium chloride; ChIP-seq; chromatin immunoprecipitation followed by DNA sequencing; C

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

TRIB3 enhances cell viability during glucose deprivation in HEK293-derived cells by upregulating IGFBP2, a novel nutrient deficiency survival factor

Keywords: فعال کردن عامل رونویسی 4; ATF4; activating transcription factor 4; eIF2α; eukaryotic translation initiation factor 2α; ER; endoplasmic reticulum; IGF; insulin-like growth factor; IGFBP2; IGF binding protein 2; TCA; trichloroacetic acid; Tet; tetracycline; TRIB3; Tribbles homolog

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis

Keywords: فعال کردن عامل رونویسی 4; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; ER; endoplasmic reticulum; IRE1α; inositol-requiring enzyme-1α; PERK; protein kinase double-stranded RNA-dependent (PRK)-like ER kinase; UPR; unfolded protein response; Br

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis

Keywords: فعال کردن عامل رونویسی 4; ALS; amyotrophic lateral sclerosis; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BAX; Bcl-2-associated X protein; Bcl-2; B cell lymphoma/lewkmia-2; BiP/Grp78; glucose-regulated protein 78; CHOP; C/EBP homologous protei

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells

Keywords: فعال کردن عامل رونویسی 4; cataracts; valproic acid; ER stress; DNA methylation; unfolded protein response; Nrf2; Keap1 promoter demethylation; ARCs; age-related cataracts; ATF4; activating transcription factor 4; BiP; immunoglobulin heavy-chain binding protein; CHOP; C/EBP-homolog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells

Keywords: فعال کردن عامل رونویسی 4; AMD; age-related macular degeneration; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; CHOP; CCAAT/enhancer-binding protein-homologous protein; C/EBP-β; CCAAT/enhancer binding protein β; CSE; cigarette smoke extract; IR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the ubiquitin-proteasome system in brain ischemia: Friend or foe?

Keywords: فعال کردن عامل رونویسی 4; 3-MA; 3-methyladenine; 15d-PHJ2; 15-deoxy-Δ12,14-prostaglandin J2; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid; AMPAR; AMPA receptors; APC/C; anaphase-promoting complex/cyclosome; APV; D-aminophosphonovalerate; ATF4; activating transcri

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells

Keywords: فعال کردن عامل رونویسی 4; ER; endoplasmic reticulum; UPR; unfolded protein response; eIF2α; eukaryotic translation initiation factor 2α; ATF4; activating transcription factor 4; PERK; RNA-dependent-protein-kinase-like ER kinase; PBA; 4-phenylbutyric acid; siRNA; small interferin

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

Keywords: فعال کردن عامل رونویسی 4; ATF-4; activating transcription factor 4; CB1; cannabinoid type-1 receptor; CB2; cannabinoid type-2 receptor; CHOP; C/EBP homologous protein; ER; endoplasmic reticulum; MEF; mouse embryonic fibroblast; mTORC1; mammalian target of rapamycin complex 1; mTOR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells

Keywords: فعال کردن عامل رونویسی 4; CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1)

Keywords: فعال کردن عامل رونویسی 4; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; ATF4; activating transcription factor 4; ca; constitutively active; dn; dominant negative; ERK; extracellular signal-related protein kinase; FBS; fetal bovine serum; GCN2; general control non-dere

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31

Keywords: فعال کردن عامل رونویسی 4; 3′UTR; 3′ untranslated region; ALP; Alkaline phosphatase; AP-1; Activator protein 1; ATF4; Activating transcription factor 4; BGLAP; Bone gamma-carboxyglutamate (gla) protein; BMP; Bone morphogenetic protein; COL1A1; Collagen, type I, alpha 1; FBS; Fe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

ER stress-induced cell death mechanisms

Keywords: فعال کردن عامل رونویسی 4; AGE; advanced glycated end-products; ALS; amyotropic lateral sclerosis; AMD; age-related macular degeneration; ARE; antioxidant response elements; ASK1; apoptotic-signaling kinase-1; ATF4; activating transcription factor 4; ATF6; activating transcription

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

Keywords: فعال کردن عامل رونویسی 4; ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BAX; Bcl2 associated X protein; BAK; BCL2-antagonist/killer; CHOP; C/EBP-homologous protein; eIF2α; eukaryotic initiation factor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Bio-informatics based analysis of genes implicated in alcohol mediated liver injury

Keywords: فعال کردن عامل رونویسی 4; (ATF4); Activating transcription factor 4; (ACOX); Acyl-CoA oxidase; (ADIPOR); Adiponectin; (ADH); Alcohol dehydrogenase; (ALDH); Aldehyde dehydrogenase; (ALAS1); 5-Aminolevulinic acid synthase-1; (ANXA2); Annexin A2; (APOB); Apolipoprotein B; (APOE); Apo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Age-related cataracts: Homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection

Keywords: فعال کردن عامل رونویسی 4; ARC; age-related cataract; ARE; antioxidant response element; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bip; ER-resident chaperone protein; CHOP; C/EBP homologous protein; DAPI; 4′,6-diamidino-2-phenylindole; DMEM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE−/− mice on a Western die

Keywords: فعال کردن عامل رونویسی 4; ATF4; activating transcription factor 4; CHOP; C/EBP homologous protein; DCF; dichlorofluorescein; ER; endoplasmic reticulum; ERO1-α; ER oxidase 1 alpha; ETC; electron transport chain; IPT3; inositol 1,4,5-triphosphate receptor; LOOH; lipid peroxide; LDL

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

DISC1-binding proteins in neural development, signalling and schizophrenia

Keywords: فعال کردن عامل رونویسی 4; DISC1; Schizophrenia; Neurodevelopment; Signalling; Synapse; Association studies; APP; Amyloid precursor protein; ATF4; Activating transcription factor 4; BACE1; β-site APP-cleaving enzyme-1; BBS4; Bardet-Biedl syndrome 4; CEP290; Centrosomal protein 2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum stress enhances γ-secretase activity

Keywords: فعال کردن عامل رونویسی 4; ER; endoplasmic reticulum; UPR; unfolded protein response; PS; presenilin; ATF4; activating transcription factor 4; GCN2; general control non-derepressible 2; PKR; protein kinase RNA; PERK; PKR-like ER kinase; HRI; heme-regulated inhibitor; eIF2α; eukary

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes

Keywords: فعال کردن عامل رونویسی 4; Integrated stress response; ATF4; Ethanol; Toxicity; Liver; CYP2E1; ISR; integrated stress response; CYP2E1; cytochrome P450 2E1; ATF4; activating transcription factor 4; HMOX-1; heme oxygenase-1; GCLC; Glutamate-cysteine ligase catalytic subunit; AsnS;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

Keywords: فعال کردن عامل رونویسی 4; 4E-BP1; 4E binding protein 1; 5′UTR; 5′ untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5′-AMP-activated protein kinase; AMPK α1−/−; AMPK α1 subunit knockout; AMPKα1−/−α2−/−; A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Adaptive Unfolded Protein Response Attenuates Alcohol-Induced Pancreatic Damage

Keywords: فعال کردن عامل رونویسی 4; Alcohol Disease; Transcription Factors; ER Protein Folding; Organelle; AMS; acetamido-maleimidylstilbene-disulfonic acid; ATF4; activating transcription factor 4; CCK-8; cholecystokinin-octapeptide; CHOP; C/EBP homologous protein; EDEM1; endoplasmic retic

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance

Keywords: فعال کردن عامل رونویسی 4; ER; endoplasmic reticulum; UPR; unfolded protein response; Grp; glucose-regulated protein; IHC; immunohistochemical; CEA; carcinoembryonic antigen; ATF4; activating transcription factor 4; NSCLC; non-small cell lung cancer; Grp78; Lung cancer; Immunohisto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Gene profiling the response to kainic acid induced seizures

Keywords: فعال کردن عامل رونویسی 4; Neurotransmitters, modulators, transporters, and receptors; Excitatory amino acids: excitotoxicity; Agt; angiotensinogen; Akt; protein kinase B; Aldr1; aldehyde reductase 1; ANPEP; alanyl aminopeptidase N; ATF4; activating transcription factor 4; Bax; BCl

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه