ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils
Keywords: آدام; ADAM; a disintegrin and metalloprotease; Neutrophil; Metalloprotease; ADAM17; Apoptosis; Fc receptor;
مقالات ISI آدام (ترجمه نشده)
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Bovine lactoferricin induces TIMP-3 via the ERK1/2-Sp1 axis in human articular chondrocytes
Keywords: آدام; OA; osteoarthritis; IL-1β; interleukin-1 β; FGF-2; fibroblast growth factor 2; ECM; extracellular matrix; TIMP; tissue inhibitor of metalloproteinase; ADAM; a disintegrin and metalloproteinase; MMP; matrix metalloproteinase; LfcinB; bovine lactoferricin
Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK
Keywords: آدام; ADAM; a disintegrin and metalloproteinase domain; AP-1; activator protein-1; ARB; angiotensin receptor blockers; AT1; angiotensin II type 1 receptor; AT2; angiotensin II type II receptor; CF; cardiac fibroblasts; CMV; cytomegalovirus; CVD; cardiovascular
Asthma and lower airway diseaseObesity impairs apoptotic cell clearance in asthma
Keywords: آدام; Asthma; obesity; inflammation; macrophage; oxidative stress; steroid; ADAM; A disintegrin and metalloproteinase domain-containing protein; BMI; Body mass index; GCR; Glucocorticoid receptor; 4HNE; 4-Hydroxynonenal; MKP-1; Mitogen-activated protein kinas
A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis
Keywords: آدام; ADAM; Osteosarcoma; Tumour growth; Bone osteolysis;
VaH3, one of the principal hemorrhagins in Vipera ammodytes ammodytes venom, is a homodimeric P-IIIc metalloproteinase
Keywords: آدام; Vipera ammodytes ammodytes; Snake venom; Hemorrhagin; Metalloproteinase; Structure; ADAM; a disintegrin and metalloproteinase; ADAMTS; ADAM with thrombospondin type-1 motif; BM; basal membrane; CR; cysteine-rich; Dis; disintegrin-like; DSF; differential s
Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17
Keywords: آدام; ADAM; A Disintegrin And Metalloprotease; TNF-α; Tumor Necrosis Factor-α; TNFR; TNF receptor; EGF; Epidermal Growth Factor; PMA; phorbol 12-myristate 13-acetate; LPA; lysophosphatidic acid; CHX; Cycloheximide; GPI; glycosylphosphatidylinositol; MAPK; mit
Névralgies du visage connues et méconnues
Keywords: آدام; Névralgie faciale; Algie vasculaire de la face; Artérite temporale; SADAM; Douleurs neuropathiques postzostériennesFacial neuralgia; Cluster headache; Temporal arteritis; ADAM; Neuropathic pain
Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size
Keywords: آدام; AAA; abdominal aortic aneurysm; ADAM; Aneurysm Detection and Management; CAESAR; Comparison of Surveillance versus Aortic Endografting for Small Aneurysm Repair; EVAR; endovascular aneurysm repair; HR; hazard ratio; PIVOTAL; Positive Impact of Endovascula
MicroRNA-145 Targets the Metalloprotease ADAM17 and Is Suppressed in Renal Cell Carcinoma Patients
Keywords: آدام; ADAM; A disintegrin and metalloproteinase; RCC; renal cell carcinoma; TNF; tumor necrosis factor;
Effects of [123I]ADAM, a serotonin transporter radiopharmaceutical, on pregnant Sprague–Dawley rats
Keywords: آدام; ADAM; Toxicity; Depression; Animal pregnancy model
On the ancestral recruitment of metalloproteinases into the venom of snakes
Keywords: آدام; Molecular evolution; Ancestral reconstruction; Toxin; Serpentes; Venom; Metalloproteinase; SVMP; ADAM;
Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3
Keywords: آدام; ADAM; a disintegrin and metalloprotease; CBB; coomassie brilliant blue; DQ; dye-quenched; Hem; hemopexin; LRP; low-density lipoprotein receptor-related protein; MMP; matrix metalloproteinase; OG; O-glycosylated; TIMP; tissue inhibitor of metalloproteinase
The double-edged sword of Notch signaling in cancer
Keywords: آدام; GSI; γ-secretase inhibitor; NRR; negative regulatory region; EGF; epidermal growth factor; LNR; Lin12/Notch repeat; ADAM; a disintegrin and metalloprotease; DSL; Delta-Serrate-Lag2; ICN; intracellular domain of Notch; MAML; Mastermind-like; RBPJ; recombi
MIG-13 controls anteroposterior cell migration by interacting with UNC-71/ADM-1 and SRC-1 in Caenorhabditis elegans
Keywords: آدام; Neural development; Q neuroblast; ADAM; Src; MIG-13
Fluid shear stress regulates metalloproteinase-1 and 2 in human periodontal ligament cells: Involvement of extracellular signal-regulated kinase (ERK) and P38 signaling pathways
Keywords: آدام; PDL; periodontal ligament; PGE2; prostaglandin E2; IL-8; interleukin-8; MMP; matrix metalloproteinase; TIMP; tissue inhibitors of metalloproteinase; MIP-1α; macrophage inflammatory protein-1α; AP-1; activator protein 1; Egr-1; early growth response prot
Notch ligand endocytosis: Mechanistic basis of signaling activity
Keywords: آدام; ADAM; a disintegrin and metalloprotease; AFM; atomic force microscopy; CSL; CBF1, Su(H), LAG-1; Dll; Delta-like; EDTA; ethylenediaminetetraacetic acid; GSI; γ-secretase inhibitor; HD; heterodimerization domain; LNRs; Lin12/Notch repeats; NECD; Notch extr
BACE1 in Alzheimer's disease
Keywords: آدام; Aβ; β-amyloid; ACDL; acid-cluster dileucine motif; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease domain protein; AICD; amyloid precursor protein intracellular domain; APLP; amyloid precursor-like protein; ApoE; apolipoprotein E; APP;
Increased expression of ADAM12 and ADAM17 genes in laser-capture microdissected breast cancers and correlations with clinical and pathological characteristics
Keywords: آدام; ADAM; a desintegrin and metalloprotease (meltrin-alpha); ADAM12L; a desintegrin and metalloprotease 12 long membrane-bound variant; ADAM12S; a desintegrin and metalloprotease 12 short secreted variant; ADAM17; a desintegrin and metalloprotease17; CDI; inv
Regulation of matrix metalloproteinases activity studied in human endometrium as a paradigm of cyclic tissue breakdown and regeneration
Keywords: آدام; ADAM; a disintegrin and metalloproteinase; ECM; extracellular matrix; EGF; epidermal growth factor; GPI; glycosylphosphatidylinositol; HSPG; heparan sulfate proteoglycan; IGF; insulin-like growth factor; IL; interleukin; LRP; low density lipoprotein recep
Snake venom metalloproteinases: Structure, function and relevance to the mammalian ADAM/ADAMTS family proteins
Keywords: آدام; Snake venom metalloproteinase; Disintegrin; MDC protein; ADAM; ADAMTS;
Dynamic expression profiles of virus-responsive and putative antimicrobial peptide-encoding transcripts during Atlantic cod (Gadus morhua) embryonic and early larval development
Keywords: آدام; ADAM; A disintegrin and metalloproteinase domain; AMP; Antimicrobial peptide; ARPC4; Actin-related protein 2/3 complex subunit 4; ATF; Activating transcription factor; BLAST; Basic local alignment search tool; C; Celsius; cAMP; Cyclic adenosine monophosph
RNA therapeutics targeting osteoclast-mediated excessive bone resorption
Keywords: آدام; 3BP2; c-Abl SH3 domain-binding protein-2; ADAM; a disintegrin and metalloproteinases; Ago; Argonaute; AP-1; activator protein-1; Ckb; brain-type creatine kinase; CNV; choroidal neovascularization; CPA; cation-proton antiporter; CPC; calcium phosphate bone
Associate editor: M.G. BelvisiMatrikines and the lungs
Keywords: آدام; aa; amino acid; ADAM; a disintegrin and metalloproteinase; APP; amyloid beta precursor; CXCR; C-X-C motif chemokine receptor; ECM; Extracellular matrix; ED; extra domains; EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; FAK; foca
Complex patterns of ADAM12 mRNA and protein splice variants in the human placenta
Keywords: آدام; WMISH; whole mount in situ hybridisation; IHC; immunohistochemistry; NB; Northern blotting; ADAM; a disintegrin and metalloprotease; EGF; epidermal growth factor; ER; endoplasmic reticulum; EGFR; epidermal growth factor receptor; IGF; insulin-like growth
Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5
Keywords: آدام; Galectin-3; Galectin-3 binding protein; Proprotein convertase 5; PTPκ shedding; ADAM; a disintegrin and metalloproteinase; LacNAc; N-acetyllactosamine; LGALS3; galectin-3; LGALS3BP; galectin-3 binding protein; MMP; matrix metalloproteinase; PC5; proprote
Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells
Keywords: آدام; α-CTF; α-cleaved carboxyterminal fragment of APP (also known as C83); Aβ; amyloid-β peptide; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease; APP; amyloid precursor protein; BACE; β-secretase; BBG; brilliant blue G; BzATP; 2â²(3â
Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing
Keywords: آدام; ADAM; a disintegrin and metalloprotease; AD; Alzheimer's disease; APP; amyloid precursor protein; ATP; adenosine-triphosphate; BSA; bovine serum albumin; CTF; C-terminal fragment; DA; docosanoic acid; DHA; docosahexaenoic acid; DMEM; Dulbecco's modified E
Effects of fatty acid unsaturation numbers on membrane fluidity and α-secretase-dependent amyloid precursor protein processing
Keywords: آدام; AA; arachidonic acid; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease; ALA; α-linolenic acid; APP; amyloid precursor protein; Aβ; amyloid-β peptide; BCA; bicinchoninic acid; BSA; bovine serum albumin; DHA; docosahexaenoic acid; DMEM; D
Drosophila metalloproteases in development and differentiation: The role of ADAM proteins and their relatives
Keywords: آدام; ADAM; Cardiogenesis; Drosophila heart morphogenesis; EMS; Genetic screening; Kuzbanian; Meltrin; Mesoderm; Neprilysin; Unc5
Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway
Keywords: آدام; ADAM; a disintegrin and metalloproteinase; BSA; bovine serum albumin; CHO-TNFÎ[1-12]; Chinese Hamster Ovary cells transfected with TNFÎ[1-12]; DKO MEF; mouse embryonic fibroblasts from TNFR1-/-/TNFR2-/- mice; EEA1; early endosomal antigen 1;
The pro- and anti-inflammatory properties of the cytokine interleukin-6
Keywords: آدام; ADAM; a disintegrin and metalloprotease; AOM; azoxymethane; CBM; cytokine-binding module; DSS; dextran sodium sulfate; Ig; immunoglobulin; IL; interleukin; mAb; monoclonal antibody; mb; membrane bound; R; receptor; STAT; signal transducer and activator of
The implications of climate policy for the impacts of climate change on global water resources
Keywords: آدام; Climate policy; Climate impacts; Mitigation; Water resources; ADAM
The multiple roles of amphiregulin in human cancer
Keywords: آدام; AREG; amphiregulin; TACE; tumor-necrosis factor-alpha converting enzyme; ADAM; a disintegrin and metalloproteinase; CTF; carboxy-terminal fragment; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EGFR-TKI; epidermal growth factor rec
Effect of posttranslational processing on the in vitro and in vivo activity of chemokines
Keywords: آدام; ADAM; a disintegrin and metalloprotease; CCL, CXCL, XCL, CX3CL; CC, CXC, C, CX3C chemokine; CCR, CXCR, XCR, CX3CR; CC, CXC, C, CX3C chemokine receptor; DPP; dipeptidyl peptidase; MCP; monocyte chemotactic protein; MIP; macrophage inflammatory protein; MMP
Extracellular proteases in epilepsy
Keywords: آدام; ADAM; a disintegrin and metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; CCI; controlled cortical impact; ECM; extracellular matrix; ECS; electroconvulsive shock; FH; complement inhibitor; GCD; granule cell disper
Role of Notch and its oncogenic signaling crosstalk in breast cancer
Keywords: آدام; 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-
Glycerophospholipids and glycerophospholipid-derived lipid mediators: A complex meshwork in Alzheimer's disease pathology
Keywords: آدام; 2-AG; 2-arachidonoylglycerol; 4-HNE; 4-hydroxynonenals; 4-HHE; 4-hydroxyhexenal; AA; arachidonic acid; Aβ; β-amyloid; ADAM; A Disintegrin And Metalloprotease; ADAPT; Alzheimer's Disease Anti-inflammatory Prevention trial; AD; Alzheimer's disease; AE
Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells
Keywords: آدام; Aβ; amyloid-beta; AD; Alzheimer's disease; ADAM; a disintegrin and metalloproteinase; APP; amyloid precursor protein; BACE; β-site APP cleaving enzyme; sAPPα; soluble amyloid precursor protein α; HIF-1α; hypoxia-inducible factor 1α; HRE; hypoxia res
Reducing agents induce thrombomodulin shedding in human endothelial cells
Keywords: آدام; ADAM; a disintegrin and metalloprotease; α-LA; α-lipoic acid; aPC; activated protein C; APMA; 4-aminophenylmercuric acetate; BSA; bovine serum albumin; CM; cytokine mixture; DHLA; dihydrolipoic acid; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; EPCR;
Research ArticleExpression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma
Keywords: آدام; HCC; hepatocellular carcinoma; VEGF; vascular endothelial growth factor; CSCs; cancer stem cells; MMP; matrix metalloproteinase; ADAM; a disintegrin and metalloproteinase; MICA; MHC class I-related chain A; Ab; antibody; siRNA; small interfering RNA; CD13
α9β1 integrin engagement inhibits neutrophil spontaneous apoptosis: Involvement of Bcl-2 family members
Keywords: آدام; ADAM; a disintegrin and metalloprotease; ECM; extracellular matrix; Erk; extracellular signal-regulated kinase; FAK; focal adhesion kinase; JNK; c-Jun kinase; NF-κB; nuclear factor-κB; PI3K; phosphatidylinositol-3-kinase; PMN; polymorphonuclear leukocyt
The disintegrin and metalloprotease Meltrin from Drosophila forms oligomers via its protein binding domain and is regulated by the homeobox protein VND during embryonic development
Keywords: آدام; ADAM; Drosophila melanogaster; Metalloprotease; Oligomerization; Redox;
Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins
Keywords: آدام; ADAM; P-III SVMP; ADAMalysin; Metzincin; Zinc-binding motif
FlipADAM: a potential new SPECT imaging agent for the serotonin transporter
Keywords: آدام; Brain imaging; SERT; 5-HTT; ADAM; IDAM; Autoradiography;
Cloning, sequencing and expression in the dog of the main amyloid precursor protein isoforms and some of the enzymes related with their processing
Keywords: آدام; Alzheimer; beta-amyloid; presenilin; BACE; ADAM; neprilysinAβ, beta-amyloid; AD, Alzheimer's disease; APP, amyloid precursor protein; CM, cardiac muscle; IDE, insulin degrading enzyme; LI, liver; LU, lung; ME, mesencephalon; PS1, presenilin 1; PS2, presen
Kininogens: More than cysteine protease inhibitors and kinin precursors
Keywords: آدام; Aging; Angiogenesis; Cathepsin; Cystatin; Cysteine protease; Kininogen; ACE; angiotensin-I-converting enzyme; ADAM; a disintegrin and metalloproteinase; ADAMT; a disintegrin and metalloproteinase with thrombospondin motifs; AMP; Antimicrobial peptide; BN-
ADAM12 is expressed by astrocytes during experimental demyelination
Keywords: آدام; ADAM; a disintegrin and metalloproteinase; APC; adenomatous polyposis coli; AT; annealing temperature; bFGF; basic fibroblast growth factor; BP; base pairs; BSA; bovine serum albumine; CC; corpus callosum; CNS; central nervous system; Cx; cortex; ctrl; co
Testosterone replacement therapy
Keywords: آدام; ADAM; delayed puberty; hypogonadism; liver dysfunction; polycythaemia; prostate cancer; sarcopenia; testosterone; testosterone replacement therapy
EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments
Keywords: آدام; EGF; HER; ADAM; Carboxy-terminal fragments (CTFs) of EGFR ligands; ErbB