Keywords: ACM; astrocyte-conditioned media; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ApoE; apolipoprotein; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CCN; CYR61/connective
مقالات ISI (ترجمه نشده)
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Keywords: ECM; extracellular matrix; ADAM; a disintegrin and metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin-like motifs; CS; chondroitin sulfate; DS; dermatan sulfate; EMT; epithelial-to-mesenchymal transition; FACIT; fibril-asso
Keywords: AAC; abdominal aortic constriction; ADAMS; a disintegrin and metalloproteases; ADAMTS; a distingetrin and metalloproteinase with a thrombospondin domain; Ang II; angiotensin II; BM; basement membrane; BMP-1; bone morphogenic protein-1; CITP; carboxy-termi
Keywords: ADAMs; a disintegrin and metalloproteinases; ADAMTS; ADAMs with thrombospondin motifs; Col; collagen; CS; chondroitin sulfate; CTGF; connective tissue growth factor; DS; dermatan sulfate; ECM; extracellular matrix; EGF; epidermal growth factor; EMT; epith
Keywords: ADAM; A Disintegrin And Metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; Akt; RAC-alpha serine/threonine-protein kinase; AP1; transcription factor AP-1; BMP; bone morphogenetic protein; DNMT; DNA methyl-transferas
Keywords: ADAMTS; A disintegrin and metalloproteinase with thrombospondin motifs; FS-PV; Fast spiking-parvalbumin neurons; GFAP; Glial fibrillary acidic protein; IP; Intraperitoneal; MAP2; Microtubule- associated protein 2; MMP; Matrix metalloproteinase; PNN; Perin
Keywords: ECM; extracellular matrix; GAG; glycosaminoglycan; MMP; matrix metalloproteinase; CS; chondroitin sulfate; ADAMTS; a disintegrin and metalloproteinase with a thrombospondin type-1 motif; PSGL-1; P-selectin glycoprotein-1; TLR; toll-like receptors; TNFα;
Keywords: PG; proteoglycan; IDD; intervertebral disc degeneration; SASP; senescence-associated secretory phenotype; SAβ-gal; senescence-associated β-galactosidase; MMP; Matrix metalloproteinase; ADAMTS; A disintegrin and metalloproteinase with thrombospondin moti
Keywords: ADAMTS; A disintegrin and metalloproteinase with thrombospondin motifs; AF; annulus fibrosus; BMP; bone morphogenic protein; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; HIF; hypoxia inducible factor; HIF-2; hypoxia inducible facto
Keywords: Bioactive fragments; Cryptome; Extracellular matrix; Matricryptins; Proteases; ADAM; A disintegrin and metalloproteinase; ADAMTS; A disintegrin and metalloproteinase with thrombospondin motif; ATP; Adenosine triphosphate; BMP-1; Bone morphogenetic protein
Keywords: extracellular matrix; retina; development; proteoglycans; phosphacan; glycoproteins; tenascin-C; degeneration; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; BM; basement membrane; ChABC; chondroitinase ABC; CSPG; chondroitin sulf
Keywords: ABC; ATP-binding cassette transporter; ACAT-1; acyl-coenzyme A acyltransferase 1; AcLDL; acetylated LDL; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ApoE; apolipoprotein E; CCL; CC-chemokine ligand; CD36; cluster of differentia
Keywords: Cytokine; Chemokine receptors; Intervertebral disc degeneration; Interleukin-1; IVD; intervertebral disc; ECM; extracellular matrix; MMP; matrix metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motif; IL-; interleukin-; T
Keywords: SLRP; small leucine-rich proteoglycan; LRR; leucine-rich repeat; RTK; receptor tyrosine kinase; GAG; glycosaminoglycan; HS; heparan sulfate; HSPG; heparan sulfate proteoglycan; He; heparin; CS; chondroitin sulfate; KS; keratan sulfate; CSPG; chondroitin s
Keywords: Decorin; Lumican; Fibromodulin; Toll-like receptor; Matrix metalloproteinases; 5/6-Nx; 5/6-nephrectomized Sprague-Dawley rats; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ALK; activin like kinase; ATS; hymocyte serum; BGN (Bgn)
Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; BMI; body mass index; DN; diabetic nephropathy; ECM; extracellular matrix, FDR, false discovery rate; LOOCV; leave one out cross-validation; MRI; magnetic resonance imaging; RCC; rena
Keywords: ACI; autologous chondrocyte implantation; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motif; AGEs; advanced glycation end products; AP-2; activator protein-2; BM MSC; bone marrow mesenchymal stem cell; BMP; bone morphogenetic protein;
Keywords: BAV; bicuspid aortic valve; BPV; bicuspid pulmonary valve; ECM; extracellular matrix; ADAMTS5; a disintegrin-like and metalloprotease domain with thrombospondin type motifs; EMT; epithelial to mesenchymal transition; WT; wild type; OFT; outflow tract; αS
Crosstalk between glia, extracellular matrix and neurons
Keywords: Extracellular matrix; Reactive astrocytes; Neuron-astrocyte signaling; ADAMTS; CNS injury;
Emodin ameliorates cartilage degradation in osteoarthritis by inhibiting NF-κB and Wnt/β-catenin signaling in-vitro and in-vivo
Keywords: Emodin; Osteoarthritis; MMPs; ADAMTS; NF-κB; Wnt/β-catenin;
The tetrapartite synapse: a key concept in the pathophysiology of schizophrenia
Keywords: ADAMS; a disintegrin and matrix metalloproteases; ADAMTS; ADAMS with a thrombospondin domain; AMPAR; α amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ATP; adenosine trisphosphate; C4; complement component 4; CS; chondroitin sulfate; CSPG; C
RNA sequencing reveals target genes of temporomandibular joint osteoarthritis in rats after the treatment of low-intensity pulsed ultrasound
Keywords: LIPUS; low-intensity pulsed ultrasound; TMJ-OA; temporomandibular joint osteoarthritis; UOT; unilateral occlusal trauma; RNA-Seq; RNA sequencing; GO; gene oncology; KEGG; kyoto encyclopedia of genes and genomes; DEGs; differentially expressed genes; qRT-P
ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma
Keywords: ADAMTS; A disintegrin and metalloprotease with thrombospondin motifs; Akt; Protein kinase serine/threonine; BCA; Bicinchoninic Acid; BSA; Bovine Serum Albumine; BrdU; Bromodeoxyuridine; CM; Conditioned medium; DAPI; Dihidrocloreto de 4â², 6â²-diamidino-
SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models
Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ADAMTS3; a disintegrin and metalloproteinase with thrombospondin motif 3; ECM; extracellular matrix; EDS; Ehlers-Danlos syndrome; SP1; specificity protein 1alpha; C/EBPα; CCAAT-enh
Aggrecanase degradation of type III collagen is associated with clinical knee pain
Keywords: Biochemical markers; Type III collagen; Pain; OA; ADAMTS; Protease-cleaved neoepitope; Biochemical marker; Knee osteoarthritis; Neoepitope; ADAMTS; A Disintigrin and Metalloproteinase with Thrombospondin motif; COL3; type III collagen; ECM; extracellular
ADAM17 promotes cell migration and invasion through the integrin β1 pathway in hepatocellular carcinoma
Keywords: ADAM17; A disintegrin and metalloproteinase-17; ADAMTS; ADAMs with thrombospondin motifs; bFGF; Basic fibroblast growth factor; EGF; epidermal growth factor; ECM; extracellular matrix; GDAC; Genome Data Analysis Center; HCC; hepatocellular carcinoma; MMP;
Spontaneous atopic dermatitis due to immune dysregulation in mice lacking Adamts2 and 14
Keywords: WT; wild type mice; TS2â/â; Adamts2-deficient mice; TS14â/â; Adamts14-deficient mice; TS2â/â/TS14â/â; Adamts2-Adamts14-deficient mice; ADAMTS; Collagen; Skin; Dermatitis; Immunity;
Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in disease
Keywords: ADAMTS; a disintegrin-like and metalloproteinase domain with thrombospondin-type 1 motifs; BMP; bone morphogenic growth factor; DEXA; longitudinal dual energy x-ray absorptiometry; ECM; extracellular matrix; FBN; fibrillin; LTBP; latent TGFβ binding prot
The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery
Keywords: ADAMs; a disintegrin and metalloproteinases; ADAMTS; ADAMs with thrombospondin motifs; BALF; bronchoalveolar lavage fluid; BAPN; β-aminopropionitrile; CD; Crohn's disease; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; EndoMT; endo
Emerging paradigms in the treatment of liver metastases in colorectal cancer
Keywords: CRC; colorectal cancer; mCRC; metastatic colorectal cancer; CLM; colorectal liver metastases; SR; surgical resection; PVE; portal vein embolism; RFA; radiofrequency ablation; APC; adenomatous polyposis coli; LOH; loss of heterozygosity; EGFR; epidermal gr
Mini-reviewThe extracellular matrix in cancer progression: Role of hyalectan proteoglycans and ADAMTS enzymes
Keywords: Extracellular matrix; Cancer; Hyalectan; Versican; ADAMTS; ACAN; aggrecan; ADAMTS; A Disintegrin-like And Metalloproteinase domain with Thrombospondin-1 motif; BCAN; brevican; CS; chondroitin sulphate; DHT; 5α-dihydrotestosterone; ECM; extracellular matr
ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'
Keywords: Osteoarthritis; Metalloproteinase; ADAMTS; ADAM;
Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling
Keywords: ADAMTS5; Brown adipose tissue; Browning; Beige; Thermogenesis; Obesity; ADAMTS; A disintesgrin and metalloproteinase with a thrombospondin type-1 motif; AT; adipose tissue; BAT; brown adipose tissue; β3-AR; beta-3 adrenergic receptor; CREB; cAMP responsi
Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes
Keywords: IL-1β; Interleukin-1β; IL-6; Interleukin-6; MMP; Matrix Metalloproteinase; ADAMTS; A Disintegrin and Metalloproteinase with Thrombospondin Motifs; COX-2; Cyclo-oxygenase-2; iNOS; Inducible Nitric Oxide Synthase; PGE2; Prostaglandin E2; COL2A1; Type 2 Co
ReviewProvisional matrix: A role for versican and hyaluronan
Keywords: ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transitions; ASMCs; arterial smooth muscle cells; GAG; glycosaminoglycan; RHAMM; receptor for hyaluronan-mediated motility; CS; chondroitin sulfate; PDGF; platelet-derived growth factor; ADAMTS; ad
Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer
Keywords: ADAM; a disintegrin and metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; AMPK; adenosine monophosphate activated protein kinase; CD44; cluster of differentiation 44; CD44s; standard CD44; CD44v; CD44 variant isofo
Osteogenesis imperfecta: new genes reveal novel mechanisms in bone dysplasia
Keywords: ADAMTS; A disintegrin and metalloprotease with thrombospondin motifs; AR-OI; autosomal recessive osteogenesis imperfecta; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; BiP; binding immunoglobulin protein; BMDD; bone mineraliz
The imbalance between TIMP3 and matrix-degrading enzymes plays an important role in intervertebral disc degeneration
Keywords: TIMP-3; Disc degeneration; Aggrecan; Nucleus pulposus; ADAMTS;
Parathyroid hormone induces expression and proteolytic processing of Rankl in primary murine osteoblasts
Keywords: Adamts; Ectodomain shedding; Osteoblast; PTH; Rankl;
Research updateOxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis
Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; AGEs; advanced glycation end products; ATG; autophagy-related gene; Col2; type II collagen; DNMT; DNA methyltransferase; ERK; extracellular signal-regulated kinase; HDAC; histone deac
MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1
Keywords: ADAMTS; adamalysin-like metalloproteinase with thrombospondin motifs; DMEM; Dulbecco's modified Eagle's medium; EEA1; early endosome antigen 1; ECM; extracellular matrix; FBS; foetal bovine serum; Hpx; hemopexin domain; LDL; low-density lipoprotein; LRP;
Autophagy: A double-edged sword in intervertebral disk degeneration
Keywords: IVD; intervertebral disk; NP; nucleus pulposus; AF; annulus fibrosus; CEPs; cartilaginous endplates; ECM; extracellular matrix; Col II; type II collagen; Col I; type I collagen; IDD; intervertebral disk degeneration; LBP; low back pain; miRNAs; microRNAs;
ROS/oxidative stress signaling in osteoarthritis
Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ATF/CRE; activating transcription factor/cyclic AMP-response element; ATF-2; activating transcription factor 2; Bach 1; broad complex-tramtrack-bric-a-brac (BTB) and cap'n'collar (CNC
Control of the basement membrane and cell migration by ADAMTS proteinases: Lessons from C. elegans genetics
Keywords: ADAMTS; Type IV collagen; Fibulin; Nidogen; Basement membrane; Organogenesis
Induction of human ADAMTS-2 gene expression by IL-1α is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells
Keywords: ADAMTS; A Disintegrin And Metalloproteinase with Thrombospondin Motifs; OA; Osteoarthritis; IL-1α; Interleukin-1 alpha; TNF-α; Tumor Necrosis Factor alpha; ECM; Extracellular Matrix; MMP; Matri Metalloproteinase; NT; Not treated; ActD; Actinomycin D; Ch
MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc
Keywords: ADAMTS; a disintergrin and metalloproteinase with thrombospondin motifs; ANOVA; analysis of variance; COX-2; cyclooxygenase-2; Ct; threshold cycle; DAB; 3, 3â²-diaminobenzidine; DMEM; Dulbecco's modified eagle medium; IHC; immunohistochemical; EGFR; epid
Induction of proteinases in the human preovulatory follicle of the menstrual cycle by human chorionic gonadotropin
Keywords: Ovulation; granulosa cell; theca cell; matrix metalloproteinase; ADAMTS;
The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology
Keywords: VEGF (-R); vascular endothelial growth factor (-receptor); MBL; mannan-binding lectin; TGF beta; transforming growth factor beta; CD31 and CD68; cluster of differentiation 31 and 68; Procollagen N-proteinases; ADAMTS; Fibrillar collagens;
ADAMTS proteases in vascular biology
Keywords: ADAMTS; angiogenesis; extracellular proteolysis; vasculature;
SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis
Keywords: Osteoarthritis; Cartilage; Chondrocyte; ADAMTS; SOX9;