دانلود مقالات ISI درباره Adcc + ترجمه فارسی

ترکیبات مختلف سیتوکین ها و محرک های گیرنده فعال برای سلول های عملکردی سلول های قاچاق انسان مورد نیاز است

Different combinations of cytokines and activating receptor stimuli are required for human natural killer cell functional diversity

Keywords: PBMCs; peripheral blood mononuclear cells; NK; natural killer cells; IL; interleukin; ADCC; antibody-dependent cell-mediated cytotoxicity; FITC; fluorescein isothiacyanate; APC; allophycocyanin; PE; phycoerythrin; PC5; Phycoerythrincyanin 5; mAbs; monoclo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

آنتی ژن های تومور هدفمند آنتی بادی های منوکلونال هدف قرار می گیرند که شامل یک دامنه چندتایی جدید می باشد، به طور قابل توجهی افزایش سمیت سلولی سلول های آنتی باکتری در برابر سرطان روده بزرگ

Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer

Keywords: ADCC; NK cell; Immunoglobulin; Fc; Fc modification; Colon cancer; FcγRIIIa; Polyvalent;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

تاثیر پیری بر عملکرد سلول های قاتل طبیعی و پیامدهای احتمالی آن در سلامت سالمندان

The impact of ageing on natural killer cell function and potential consequences for health in older adults

Keywords: ADCC; antibody dependent cell cytotoxicity; Apaf-1; apoptosis-activating factor 1; BID; BH3-interacting domain; CAD; caspase-activated DNase; CMV; cytomegalovirus; DC; dendritic cell; DLN; draining lymph node; FasL; Fas ligand; FADD; Fas-associated protei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

برون یابی حیوانات در مطالعات بالینی: تجزیه و تحلیل مورد غم انگیز از TGN1412

Animal extrapolation in preclinical studies: An analysis of the tragic case of TGN1412

Keywords: Animal extrapolation; Preclinical studies; Experimental organism; Prediction; Mechanistic thinking; Ab; Antibody; ADCC; Antibody-Dependent Cell-Mediated Cytotoxicity; ADME; Absorption, Distribution, Metabolism, Excretion; CDC; Complement-Dependent Cytotox

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of amino acid substitutions on the biological activity of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori)

Keywords: Monoclonal antibody; Transgenic silkworm; Amino acid substitution; N-glycosylation; Fc-mediated effector function; ADCC; antibody-dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; CBB; Coomassie Brilliant Blue; CDC; compleme

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Report on eighth WHO meeting on development of influenza vaccines that induce broadly protective and long-lasting immune responses: Chicago, USA, 23-24 August 2016

Keywords: Influenza; Pandemic influenza vaccine; Seasonal influenza vaccine; Universal influenza vaccine; Vaccine development; Nextgeneration influenza vaccine; ADCC; Antibody-dependent cell-mediated cytotoxicity; AE; Adverse event; CMI; cell-mediated immunity; CON

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Elimination of eosinophils using anti-IL-5 receptor alpha antibodies effectively suppresses IL-33-mediated pulmonary arterial hypertrophy

Keywords: ADCC; antibody dependent cell-mediated cytotoxicity; IL; IL-5; IL-5Rα; IL-5 receptor α chain; ILC2; group 2 innate lymphoid cell; Th2; T helper type 2; PAH; pulmonary arterial hypertension; CDR; complementary determining region; SMA; smooth muscle actin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of a putative glutathione S-transferase of the parasitic nematode Trichinella spiralis

Keywords: Trichinella spiralis; Glutathione S-transferase; Biological characteristics; Invasion; ADCC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individuals

Keywords: HIV-1; Envelope glycoproteins; States 2/3; CD4; Non-neutralizing antibodies; ADCC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Gene signatures and expression of miRNAs associated with efficacy of panitumumab in a head and neck cancer phase II trial

Keywords: Head and neck cancer; Recurrent/metastatic; Anti-EGFR; Second line treatment; Progression-free survival; Gene expression signatures; Hypoxia signature; Microenvironment score; miRNA; EGFR; epidermal growth factor receptor; mAb; monoclonal antibody; RM; re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Transitioning from first- to second-generation biosimilars: An appraisal of regulatory and post-marketing challenges

Keywords: ACR; American College of Rheumatology; ADAb; anti-drug antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; AIFA; Italian Medicines Agency; CDC; complement-dependent cytotoxicity; CHMP; Committee for Medicinal Products for Human Use; DAS28; 28-j

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

ABO phenotype-protected reproduction based on human specific α1,2 L-fucosylation as explained by the Bombay type formation

Keywords: ADCC; antibody-dependent (mediated) cellular cytotoxicity; A2M; α2-macroglobulin; Ab; antibody; EGF; epidermal growth factor; Ig; immunoglobulin; IgG; immunoglobulin G; IgM; immunoglobulin M; GC; germ cell(s); ESC; embryonic stem cell(s); D-GalNAc; N-ace

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic monoclonal antibody N-glycosylation - Structure, function and therapeutic potential

Keywords: IgG; Glycans; Glycosylation; Fc-receptors; ADCC; ADCP; CDC; Effector function; Therapeutic antibodies;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Glycosimilarity assessment of biotherapeutics 1: Quantitative comparison of the N-glycosylation of the innovator and a biosimilar version of etanercept

Keywords: APTS; 8-aminopyrene-1,3,6-trisulfonic acid; CGE-LIF; capillary gel electrophoresis - laser induced fluorescence; CQA; critical quality attributes; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; Fc; fragment

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular adjuvants that modulate regulatory T cell function in vaccination: A critical appraisal

Keywords: ADCC; antibody dependent cell cytotoxicity; CD; cluster of differentiation; mAb; monoclonal antibody; CsA; cyclosporine; CTLA-4; T-lymphocyte antigen 4; GITR; glucocorticoid-induced tumor necrosis factor receptor (TNFR) family related gene; CCR4; C-C chem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Dysregulated Response of Follicular Helper T Cells to Hepatitis B Surface Antigen Promotes HBV Persistence in Mice and Associates With Outcomes of Patients

Keywords: Viral Hepatitis; Immune Regulation; Neutralizing Antibody Response; Immunotherapy; ADCC; antibody-dependent cell-mediated cytotoxicity; anti-HBs; antibodies specific for hepatitis B surface antigen; ASC; antibody-secreting cell; CHB; chronic hepatitis B;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Identifying systemic important markets from a global perspective: Using the ADCC ΔCoVaR approach with skewed-t distribution

Keywords: Systemic risk contribution; Global financial crisis; ADCC; CoVaR; C30; C50; G10;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

A novel Ebola virus antibody-dependent cell-mediated cytotoxicity (Ebola ADCC) assay

Keywords: Ebola viral disease; Zaire; Ebolavirus; ADCC; Ebola glycoprotein;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations

Keywords: Signal transducer and activator of transcription 1, gain of function; natural killer cell deficiency; perforin; Janus kinase inhibition; ruxolitinib; natural killer cell maturation; ADCC; Antibody-dependent cellular cytotoxicity; CCD; Coiled-coil domain;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Do commodities effectively hedge real estate risk? A multi-scale asymmetric DCC approach

Keywords: G15; Q43; Commodities; Gold; Real estate; ADCC; Hedge ratios;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Novel mutant P277 peptide VP to ameliorate atherogenic side-effects and to preserve anti-diabetic effects in NOD mice

Keywords: T1DM; type 1 diabetes mellitus; NOD; non-obese diabetes; HUVECs; human umbilical vein endothelial cells; MHC; major histocompatibility complex; Hsp 60; heat shock protein 60; HCD; high cholesterol diet; LCD; low high cholesterol diet; OVA; ovalbumin; KLH;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Understanding the biology of HER3 receptor as a therapeutic target in human cancer

Keywords: Ab; antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; FDA; Food and Drug Administration; HER; Human epidermal growth factor receptor; HRG; heregulin; IGF-1R; insu

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases

Keywords: IBD; Glycans; Glycopeptides; Biomarker; A2; diantennary; A2B; structures with bisecting β(1,4) N-acetylglucosamine; A2F; fucosylated structures; ADCC; antibody-dependent cellular cytotoxicity; anti-TNF; inhibitor of tumor necrosis factor; AUC; area unde

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Early Stage HER2-Positive Breast Cancers Not Achieving a pCR From Neoadjuvant Trastuzumab- or Pertuzumab-Based Regimens Have an Immunosuppressive Phenotype

Keywords: ADCC; Antibody-dependent cellular cytotoxicity; FoxP3; Regulatory T cell; T-cell receptor; Tumor immune microenvironment;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Neutrophils mediate HIV-specific antibody-dependent phagocytosis and ADCC

Keywords: HIV-1; human immunodeficiency virus 1; ADP; antibody-dependent phagocytosis; ADNP; antibody dependent neutrophil phagocytosis; ADCC; antibody dependent cellular cytotoxicity; RFADCC; rapid-fluorometric Antibody dependent cellular cytotoxicity; CFSE; carbo

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica

Keywords: AQP4; NMO; Fc multimer; Astrocyte; Complement; Immunoglobulin; Neuroinflammation; ADCC; antibody-dependent cellular cytotoxicity; AQP4; aquaporin-4; AQP4-IgG; neuromyelitis optica immunoglobulin G antibody; BSA; bovine serum albumin; CDC; complement-depen

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

The cataract-causing mutation G75V promotes γS-crystallin aggregation by modifying and destabilizing the native structure

Keywords: ADCC; autosomal dominant congenital cataract; ANS; 1-anilinonaphtalene-8-sulfonate; BSA; bovine serum albumin; CD; circular dichroism; DTT; dithiothreitol; Emax; maximum emission wavelength of intrinsic Trp fluorescence; GdnHCl; guanidine hydrochloride; I

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

An improved method to quantify human NK cell-mediated antibody-dependent cell-mediated cytotoxicity (ADCC) per IgG FcR-positive NK cell without purification of NK cells

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; CD16A; cluster of differentiation designation for the Fc-gamma type III low affinity receptor for IgG, found on NK cells; CD20; cluster of differentiation designation for a B cell surface protein; CX1:1

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy

Keywords: αβ; alpha beta; ADCC; antibody-dependent cellular cytotoxicity; APC; antigen-presenting cell; BrHPP; bromohydrin pyrophosphate; BTLA; B and T lymphocyte attenuator; CAR; chimeric antigen receptor; DC; dendritic cell; γc; common gamma; γδ; gamma delta

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Rationale for combination of therapeutic antibodies targeting tumor cells and immune checkpoint receptors: Harnessing innate and adaptive immunity through IgG1 isotype immune effector stimulation

Keywords: ADCC; Cetuximab; CTLA-4; PD-L1; PD-1; Immunotherapy;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Implications of uterine NK cells and regulatory T cells in the endometrium of infertile women

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; ART; assisted reproductive technology; dNK cells; decidual natural killer cells; CTLA-4; cytotoxic T-lymphocyte antigen-4; EVT; extra-villous trophoblast; G-CSF; granulocyte colony-stimulating factor; G

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Aptamers as potential therapeutic agents for ovarian cancer

Keywords: Aptamers; Antibodies; EpCAM; Therapeutic; Targeted therapies; Ovarian cancer; ADCC; antibody-dependent cell-mediated cytotoxicity; ABC; ATP-binding cassette; BBB; blood brain barrier; CDC; complement-mediated cytolysis; CA125; Cancer Antigen 125; CSCs; ca

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer

Keywords: Gold nanoparticle; Trastuzumab resistance; HER2; Gastric cancer; Autophagy; Tmab; trastuzumab; HER2; human epidermal growth factor receptor 2; AuNP; gold nanoparticle; ECD; extracellular domain; ADCC; antibody-dependent cellular cytotoxicity; PTEN; phosph

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Plasma N-glycome composition associates with chronic low back pain

Keywords: Glycan biomarker; Low back pain; Plasma N-glycosylation; Retrospective study; % Area; percentage of total integrated area of the chromatogram; 2-AB; 2-aminobenzamide; 2-PB; 2-picoline borane; AbSur; cohort of patients with acute inflammation that had abdo

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

Keywords: ADCC; antibody dependent cell-mediated cytotoxic activity; ALL; acute lymphoid leukemia; AML; acute myeloid leukemia; CXCL; C-X-C motif chemokine ligand; ECM; extra-cellular matrix; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulat

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Redox control of cancer cell destruction

Keywords: ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Bispecific antibodies for cancer therapy: A review

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AE; adverse events; ALL; acute lymphoblastic leukemia; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; B-ALL; B-cell acute lymphoblastic leukemia; BiTES; Bi-sp

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell

Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Membrane-anchored stalk domain of influenza HA enhanced immune responses in mice

Keywords: Influenza virus; Stalk domain; (GGGGS)4 linkers; Virus-like particles; ADCC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Cytokines for the induction of antitumor effectors: The paradigm of Cytokine-Induced Killer (CIK) cells

Keywords: ACT; Adoptive cell transfer; ADCC; Antibody-Dependent Cell-mediated Cytotoxicity; CAR; Chimeric antigen receptor; CIK; Cytokine Induced Killer cells; CMV; Cytomegalovirus; EGFR; Human epidermal growth factor 1; GVHD; Graft-versus-Host disease; ICI; Immune

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperNK cell degranulation as a marker for measuring antibody-dependent cytotoxicity in neutralizing and non-neutralizing human sera from dengue patients

Keywords: Dengue virus; ADCC; NK cell degranulation; Dengue serum; CD16;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperDevelopment of IFN-γ secretory ELISPOT based assay for screening of ADCC responses

Keywords: HIV; ADCC; IFN-γ; ELISPOT; ICS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

B cell depleting therapy regulates splenic and circulating T follicular helper cells in immune thrombocytopenia

Keywords: Immune thrombocytopenia; T follicular helper cells; Rituximab; ADCC; antibody-dependent cell-mediated cytotoxicity; AID; autoimmune diseases; FC; fold change; GC; germinal center; ITP; immune thrombocytopenia; PBMC; peripheral blood mononuclear cells; PBL

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Development of a complete human IgG monoclonal antibody to transferrin receptor 1 targeted for adult T-cell leukemia/lymphoma

Keywords: Anti-transferrin receptor 1 antibody; Adult T-cell leukemia/lymphoma; Phage display; Direct cytotoxicity; ADCC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura)

Keywords: ADCC; antibody-dependent cellular cytotoxicity; AECA; Anti-epithelial cell antibodies; ANCA; Anti-neutrophil cytoplasmic antibodies; β2GPI; β2-glycoprotein I; CDC; Complement-dependent cytotoxicity; EC; endothelial cell; FcαRI; Fc receptor for IgA; Gal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Quantitative in vitro and in vivo models to assess human IgE B cell receptor crosslinking by IgE and EMPD IgE targeting antibodies

Keywords: aa; amino acids; AB; antibody; ADCC; antibody dependent cellular cytotoxicity; BCR; B cell receptor; cQui; chimeric form of the humanized V region of Quilizumab and the murine C region of IgG2a heavy and kappa light chain; dox; Doxycycline; EMPD; Extracel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Predictors of durable immune responses six months after the last vaccination in preventive HIV vaccine trials

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AUC; area under the receiver operating characteristics curve; BAMA; binding antibody multiplex assay; CI; confidence interval; CV; cross-validation; ELISA; enzyme-linked immunosorbent assay; ELISpot; en

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Single N277A substitution in C2 of simian immunodeficiency virus envelope influences vaccine-elicited CD4i neutralizing and anti-V2 antibody responses

Keywords: HIV; CD4-induced; Mutagenesis; V2; ADCC; Vaccine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperThaw-and-use target cells pre-labeled with calcein AM for antibody-dependent cell-mediated cytotoxicity assays

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; mAb; monoclonal antibody; NK; natural killer, PBMC, peripheral blood mononuclear cell; EC50; half maximal effective concentration; ET ratio; effector cell:target cell ratio; Fc; fragment crystallizable;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models

Keywords: ADC; antibody-drug conjugate; NHL; non-Hodgkin lymphoma; DLBCL; diffuse large B-cell lymphoma; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; MMAE; monomethyl auristatin E; SMCC; N-succinimidyl-4-(N-maleimidoe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه