دانلود مقالات ISI درباره Adcc + ترجمه فارسی

The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models

Keywords: ADC; antibody-drug conjugate; NHL; non-Hodgkin lymphoma; DLBCL; diffuse large B-cell lymphoma; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; MMAE; monomethyl auristatin E; SMCC; N-succinimidyl-4-(N-maleimidoe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperCharacterization of FcγRIIIA effector cells used in in vitro ADCC bioassay: Comparison of primary NK cells with engineered NK-92 and Jurkat T cells

Keywords: mAbs; monoclonal antibodies; Fab; fragment antigen-binding; Fc; fragment crystallizable; NK cells; natural killer cells; ADCC; antibody-dependent cell-mediated cytotoxicity; MOA; mechanisms of action; NFAT; nuclear factor of activated T cells; T cells; th

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles

Keywords: Antibody; Effector function; ADCC; Phagocytosis; Vaccines; IgG;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of Different Parameters of Humoral and Cellular Immune Responses in HIV Serodiscordant Heterosexual Couples: Humoral Response Potentially Implicated in Modulating Transmission Rates

Keywords: HIV-1; Serodiscordant couples; ADCC; HIV-1 transmission;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis

Keywords: Ab; Antibodies; ADCC; Antibody-dependent cellular cytotoxicity; Ag; Antigen; BLAST; Basic local alignment search tool; BSA; Bovine serum albumin; CDC; Complement-dependent cytotoxicity; CDRs; Complementarity determining regions; CHO; Chinese hamster ovary

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Antibodies targeting BTLA or TIM-3 enhance HIV-1 specific T cell responses in combination with PD-1 blockade

Keywords: PD-1; BTLA; TIM-3; CD160; LAG-3; CTLA-4; Immune checkpoints; Coinhibitory receptors; T cell exhaustion; HIV-1; ADCC; antibody dependent cellular cytotoxicity; (c)ART; (combined) antiretroviral therapy; CDC; complement dependent cytotoxicity; CFSE; Carboxy

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection

Keywords: HIV; human immunodeficiency virus; Env; HIV envelope protein; cART; combined antiretroviral therapy; EC; elite controller; IgG; immunoglobulin G; (n)Ab; (neutralizing) antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; CTL; cytotoxic T cell; T

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Chimeric antigen receptor-engineered natural killer and natural killer T cells for cancer immunotherapy

Keywords: aAPC; artificial antigen-presenting cells; αGalCer; α-galactosylceramide; ACT; adoptive cell transfer; ADCC; antibody-dependent cell-mediated cytotoxicity; ALL; Acute Lymphoblastic Leukemia; AML; acute lymphoid leukemia; CAR; chimeric antigen receptor;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis

Keywords: Crohn's Disease; Fcγ Receptor; Drug Modification; Mouse Model; ADA; adalimumab; ADA−ΔF; hypo-fucosylated ADA; ADCC; antibody-dependent cellular cytotoxicity; FcγR; Fcγ-receptors; IBD; inflammatory bowel disease; IFNγ; interferon γ; Ig; immunoglo

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Report of the Cent Gardes HIV Vaccines Conference. Part 1: The antibody response; Fondation Mérieux Conference Center, Veyrier-du-Lac, France, 25-27 October 2015

Keywords: HIV; Neutralizing antibodies; B cell lineage; Passive immunization; ADCC; Mucosal immunity;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Fc-galactosylation modulates antibody-dependent cellular cytotoxicity of therapeutic antibodies

Keywords: Galactosylation; Fucosylation; Afucosylation; Fc-glycan; ADCC; CDC; Effector function; Natural killer cell; IgG1; Antibody;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Sialylation of antibodies in kidney recipients with de novo donor specific antibody, with or without antibody mediated rejection

Keywords: Ab; antibody; ABTS; 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid); ADCC; antibody dependent cell-mediated cytotoxicity; AMR; antibody mediated rejection; ATG; Anti ThymoGlobulin; CHR; chronic humoral rejection; DC-SIGN; dendritic cell-specific

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Chimeric peptide containing both B and T cells epitope of tumor-associated antigen L6 enhances anti-tumor effects in HLA-A2 transgenic mice

Keywords: Peptide; Antibody-dependent cellular cytotoxicity; Cytotoxic T lymphocytes; TAL6; TM4SF1; IFA; incomplete Freund's adjuvant; PELC; poly(ethylene glycol)-block-poly(lactideco-e-caprolactone) with squalene and Span®85; TAL6; tumor-associated antigen L6; TM

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Cross-protective efficacies of highly-pathogenic avian influenza H5N1 vaccines against a recent H5N8 virus

Keywords: HPAI H5N1; H5N8; Vaccine; ADCC; Cross-protection;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The modified FACS calcein AM retention assay: A high throughput flow cytometer based method to measure cytotoxicity

Keywords: Cancer; Cellular cytotoxicity; ADCC; CDC; Monoclonal antibodies;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

M2SR, a novel live single replication influenza virus vaccine, provides effective heterosubtypic protection in mice

Keywords: ADCC; antibody-dependent cellular cytotoxicity; Aichi; influenza A/Aichi/2/1968; APC; allophycocyanin; BAL; bronchoalveolar lavage; BSA; bovine serum albumin; CPE; cytopathic effect; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; HAI; hemaggluti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Susceptibility and resistance to Echinococcus granulosus infection: Associations between mouse strains and early peritoneal immune responses

Keywords: Susceptibility; Resistance; Cytokines; PCA; ADCC; Nitric oxide; Balb/c; C57Bl/6;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

An FDA oncology analysis of immune activating products and first-in-human dose selection

Keywords: MABEL; Immune oncology; First-in-human dose; ADCC; antibody-dependent cellular cytotoxicity; CRA; cytokine release assay; CRS; cytokine release syndrome; DLT; dose limiting toxicity; EMA; European Medicines Agency; FIH; first-in-human; HHD; highest human

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of high-affinity anti-CD16A allotype-independent human antibody domains

Keywords: Natural killer (NK) cells; CD16A; ADCC; Antibody domains; BiKE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Near infrared photoimmunotherapy of B-cell lymphoma

Keywords: Near infrared photoimmunotherapy; CD20; B-cell lymphoma; Monoclonal antibodies; Near infrared light; Molecular imaging; ADCC; antibody-dependent cell-mediated cytotoxicity; APC; antibody-photo absorber conjugate; CD; cluster of differentiation; CDC; compl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

Keywords: HIV-1; Envelope glycoproteins; CD4; Non-neutralizing antibodies; ADCC; CD4-mimetics;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Association and multiple interaction analysis among five XRCC1 polymorphic variants in modulating lung cancer risk in North Indian population

Keywords: LC; lung cancer; SQCC; squamous cell carcinoma; ADCC; adenocarcinoma; SCLC; small cell lung carcinoma; OR; odds ratio; 95% CI; 95% confidence interval; PY; pack years; SD; standard deviation; CVC; cross validation consistency; MDR; multi-dimensionality re

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

Keywords: HIV-1; Envelope glycoproteins; gp120; CD4; CD4-bound conformation; Non-neutralizing antibodies; ADCC; CD4-mimetics; Bystander killing

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

Keywords: ADCC; Antibody-dependent cell-mediated cytotoxicity; ARV; Anti-retroviral; AZT; Zidovudine; bnAb; Broadly neutralizing antibody; CD4bs; CD4 binding site; dIgA; Dimeric IgA; FcRn; Neonatal Fc receptor; GalCer; Galactosyl ceramide; GI; Gastrointestinal; GU;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Immunoreceptors on neutrophils

Keywords: ADCC; antibody-dependent cellular cytotoxicity; ANCAs; anti-neutrophil autoantibodies; Btk; Bruton's tyrosine kinase; DAG; diacyl-glycerol; DAP12; DNAX activation protein of 12 kDa; ERK; extracellular signal-regulated kinase; fMLP; N-Formylmethionine-leu

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer

Keywords: HER2; Trastuzumab; ADCC; Chemoresistance; Small-cell lung cancer; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Fsn0503h antibody-mediated blockade of cathepsin S as a potential therapeutic strategy for the treatment of solid tumors

Keywords: Cathepsin S; Fsn0503h antibody; Cathepsin S blockade; Cell invasiveness; Colo-205 xenografts; ADCC; antibody-dependent cellular cytotoxicity; ANOVA; analysis of variance; Cat-S; cathepsin S; DMSO; dimethyl sulfoxide; ECM; extracellular matrix; Emax; maxim

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding

Keywords: Fc; fragment crystallizable; IgG; immunoglobulin G; Fab; fragment antigen binding; FcγR; Fc gamma receptor; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; CDC; complement-dependent cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Report on the second WHO integrated meeting on development and clinical trials of influenza vaccines that induce broadly protective and long-lasting immune responses: Geneva, Switzerland, 5-7 May 2014

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; CMI; cell-mediated immunity; COBRA; computationally optimized broadly reactive antigen; CoP; immune correlate of protection; HA; influenza haemagglutinin protein; HI; haemagglutination inhibition; IFN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

A PSA-guided approach for a better diagnosis of prostatic adenocarcinoma based on MALDI profiling and peptide identification

Keywords: ADCC; antibody dependent cell-mediated cytotoxicity; AMACR; alpha-methylacyl-CoA racemase; DRE; digital rectal endoscopy; HAP; high abundance proteins; LAP; low abundance proteins; PCa; prostate cancer; PCA3; prostate cancer antigen 3; PSA; prostate-speci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Trastuzumab enhanced the cytotoxicity of Vγ9Vδ2 T cells against zoledronate-sensitized osteosarcoma cells

Keywords: Vγ9Vδ2 T cells; Osteosarcoma; Zoledronate; Monoclonal antibodies; Trastuzumab; ADCC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; AP; alkaline phosphatase; CDC; complement-mediated cytotoxicity; CH2; constant domain 2; DNP; 2,4-dinitrophenyl; EDTA; ethylenediaminetetraacetic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

In vivo anti-tumor efficacy of afucosylated anti-CS1 monoclonal antibody produced in glycoengineered Pichia pastoris

Keywords: Afucosylation; Anti-CS1; HuLuc63; ADCC; Monoclonal antibodies; Multiple myeloma; Pichia pastoris; N-glycosylation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

An FDA oncology analysis of antibody-drug conjugates

Keywords: AD; acceptable dose; ADC; antibody-drug conjugate; ADCC; antibody-dependent cellular cytotoxicity; FIH; first-in-human; HNSTD; highest non-severely toxic dose; ICH; International Conference on Harmonization; LC/MS; liquid chromatography/mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Developing vaccines to prevent sustained infection with Mycobacterium tuberculosis: Conference proceedings

Keywords: ADCC; antibody directed cellular cytotoxicity; AIR; Airborne Infections Research Facility; BCG; Bacille Calmette-Guérin; CFP-10; 10 kDa culture filtrate protein; CFU; colony forming units; CM; cynomolgous macaques; CMI; cell mediated immunity; CT; compu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Genetic polymorphisms in GSTM1, GSTT1 and GSTP1 genes and risk of lung cancer in a North Indian population

Keywords: LC; lung cancer; SQCC; squamous cell carcinoma; ADCC; adenocarcinoma; SCLC; small cell lung carcinoma; GSTs; glutathione-S-transferases; OR; odds ratio; 95% CI; 95% confidence interval; PY; pack years; SD; standard deviation; ETS; environmental tobacco sm

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewPreclinical and clinical development of inotuzumab-ozogamicin in hematological malignancies

Keywords: Ab; antibody; ADC; antibody-drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; AE; adverse event; ALL; acute lymphoblastic leukemia; AUC; the area under the plasma concentration time curve; AUCtau; area under the curve extrapolated ove

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Associate editor: B. TeicherCD70: An emerging target in cancer immunotherapy

Keywords: CD70; CD27; Cancer immunotherapy; Combination therapy; ADCC; Antibody-dependent cellular cytotoxicity; ADCP; Antibody-dependent cellular phagocytosis; CDC; Complement-dependent cellular cytotoxicity; CTLA-4; Cytotoxic T lymphocyte antigen-4; FOXP3; Forkhe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge

Keywords: Ab; antibody; mAb; monoclonal antibody; nmAb; neutralizing monoclonal antibody; ADCC; antibody-dependent cellular cytotoxic activity; AID50; 50% animal infectious doses; C1; first conserved region; CTL; cytotoxic T lymphocyte; dIgA; dimeric IgA; Env; enve

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Immunotherapy with mutated onchocystatin fails to enhance the efficacy of a sub-lethal oxytetracycline regimen against Onchocerca ochengi

Keywords: ADCC; antibody-mediated cellular cytotoxicity; ADT; adulticidal antibiotic therapy; CON; untreated control; CPI; cysteine proteinase inhibitor; IRAD; Institut de Recherche Agricole pour le Développement; OD; optical density; OVC; onchocystatin vaccine co

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewMast cells as targets for immunotherapy of solid tumors

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; FcɛRI; high affinity IgE Fc receptor; FcγRI; high affinity IgG Fc receptor; FcγRII; low affinity IgG Fc receptor; FGF; fibroblast growth factor; H1-H4; histamine receptors 1-4; HIF-1α; hypoxia i

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewAlternative molecular formats and therapeutic applications for bispecific antibodies

Keywords: ADCC; antibody-dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; ALL; acute lymphoblastic leukemia; AMD; age-related macular degeneration; AML; acute myeloid leukemia; BsAb; bispecific antibody; BsIgG; bispecific IgG; CDC; c

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The relevance of ADCC for EGFR targeting: A review of the literature and a clinically-applicable method of assessment in patients

Keywords: ADCC; Antitumor monoclonal antibody; Natural Killer; Cellular immunity; Cetuximab

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans

Keywords: ADCC; RF-ADCC; Antibody; HIV; CD4-induced; CD4i; C11; Potency; Breadth

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins

Keywords: mAb; glycosylation; Fc-fusion; pharmacokinetics; pharmacodynamics; ADCC; CDC; biosimilar; immunogenicity

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Low antibody-dependent cellular cytotoxicity responses in Zambians prior to HIV-1 intrasubtype C superinfection

Keywords: HIV-1 superinfection; ADCC; HIV-1 ADCC; HIV dual infection;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Next-generation optimized biotherapeutics - A review and preclinical study

Keywords: ADAs; anti-drug antibodies; ADC; antibody drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; ATL; adult T-cell leukemia-lymphoma; CCR4; CC chemokine receptor 4; CDC; complement-dependent cytotoxicity; CDR; complementary determining regio

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Antibody-dependent cellular cytotoxicity and cytokine/chemokine secretion by KHYG-1 cells stably expressing FcγRIIIA

Keywords: mAb; monoclonal antibody; ADCC; antibody-dependent cellular cytotoxicity; RTX; rituximab; TRA; trastuzumab; NK cell; natural killer cell; PBMC; peripheral blood mononuclear cell; NK cells; KHYG-1 cells; CD16A; FcγRIIIA; ADCC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleA phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma

Keywords: IgG1; Immunoglobulin 1; IGF-1R; Insulin growth factor 1 receptor; IGF-1; Insulin growth factor 1; MAP; Mitogen activated protein; ADCC; Antibody-dependent complement-mediated cytotoxicity; CDC; Complement-dependent cytotoxicity; IGF-2; Insulin growth fact

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Ex vivo-expanded natural killer cells kill cancer cells more effectively than ex vivo-expanded γδ T cells or αβ T cells

Keywords: ADCC; antibody-dependent cellular cytotoxicity; E/T ratio; effector-to-target ratio; FcγR; Fcγ receptor; mAb; monoclonal antibody; MHC; major histocompatibility complex; NCR; natural cytotoxicity receptor; NK cell; natural killer cell; PBMCs; peripheral

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه