دانلود مقالات ISI درباره Adcc + ترجمه فارسی

Crystal structure of a novel asymmetrically engineered Fc variant with improved affinity for FcγRs

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; A/I ratio; activating FcγR binding to inhibitory FcγR binding; asym-mAb23; a novel asymmetrically engineered Fc; FcγR; Fcγ receptor; mAb; monoclo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Progress in HIV-1 vaccine development

Keywords: HIV-1; vaccine; T cells; B cells; broadly neutralizing antibodies; ADCC; Antibody-dependent cellular cytotoxicity; BCR; B-cell antigen receptor; bnAb; Broad neutralizing antibody; Env; Envelope; gp; Glycoprotein; HC; Heavy chain; HCDR3; Immunoglobulin thi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Comparison of the glycosylation of in vitro generated polyclonal human IgG and therapeutic immunoglobulins

Keywords: ADCC; antibody-dependent cellular cytotoxicity; FBS; fetal bovine serum; F; deoxyhexose (fucose); Gal; galactose; GlcNAc; N-acetylglucosamine; H; hexose, Hex; IVIG; intravenous immunoglobulin; LC; liquid chromatography; LTQ; linear trap quadrupole; MS; ma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in 51Cr-release and CD107a assays

Keywords: PBMC, peripheral blood mononuclear cells; ADCC, antibody-dependent cell mediated cytotoxicity; NK, natural killer cellsCryopreservation; PBMC; NK cells; ADCC; Degranulation; CD107a

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Boosting ADCC and CDC activity by Fc engineering and evaluation of antibody effector functions

Keywords: ADCC; CDC; Antibody engineering; Fc modification; Antibody glycosylation; Antibody therapy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of a fully human monoclonal antibody against multiple influenza A viral strains in mice and a pandemic H1N1 strain in nonhuman primates

Keywords: M2; matrix protein 2; M2e; ectodomain of M2; mAb; monoclonal antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; HA; hemagglutinin; NA; neuraminidase; Influenza A; Matrix protein 2; Antibody; Virus infect

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Multimodality vaccination against clade C SHIV: Partial protection against mucosal challenges with a heterologous tier 2 virus

Keywords: HIV vaccine; SHIV-C; Heterologous tier 2 virus; Rhesus monkey; Cellular immunity; ADCC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A novel FcγRIIa Q27W gene variant is associated with common variable immune deficiency through defective FcγRIIa downstream signaling

Keywords: FcγR; Fc gamma receptor; CVID; common variable immunodeficiency; ITAM; immunoreceptor tyrosine-based activation motif; BCR; B cell receptor; DC; dendritic cells; MAPK; mitogen-activated protein kinase; PBMC; peripheral blood mononuclear cells; ADCC; anti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Expansion of NK cells by engineered K562 cells co-expressing 4-1BBL and mMICA, combined with soluble IL-21

Keywords: NK cell; natural killer cell; 4-1BBL; 4-1BB ligand; mMICA; membrane-bound MHC class I chain-related protein A; sIL-21; soluble interleukin 21; PBMCs; peripheral blood mononuclear cells; sMICA; soluble MICA; ADCC; Ab-depend cell cytotoxicity; TNF; tumor ne

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Creating stable stem regions for loop elongation in Fcabs - Insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations

Keywords: IgG1; immunoglobulin G class 1; IgG1-Fc; crystallizable fragment of immunoglobulin G class 1; Fc-wt; recombinant wild-type human IgG1-Fc; Fab; antigen binding fragment; mAb; monoclonal antibody; scFv; single-chain variable fragment; FcγRI; Fcγ-receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative functional characterization of canine IgG subclasses

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; cell-mediated cytotoxicity; CDR; complementarity determining region; Canine; Immunoglobulin; IgG subclass; Fc receptor; Effector functions;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

A systematic review of dual targeting in HER2-positive breast cancer

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; ASCO; American Society of Clinical Oncology; CBR; clinical benefit rate; CHF; congestive heart failure; CI; confidence interval; DFS; disease free survival; EGFR; epidermal growth factor receptor; ER; e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Antilymphocyte autoantibodies generate T cell-C4d signatures in systemic lupus erythematosus

Keywords: ADCC; antibody-dependent cellular cytotoxicity; ALA; antilymphocyte autoantibodies; CB-CAPs; cell-bound complement activation products; C4d; complement C4 activation product C4d; Ig; immunoglobulin; T-C4d; T cell-bound C4d; SLE; systemic lupus erythema

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; PBMC; peripheral blood mononuclear cell; NK cells; natural killer cells; LDH; lactate dehydrogenase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; EC50; measur

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations

Keywords: ADCC; antibody-dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; BSA; bovine serum albumin; CDC; complement dependent cytotoxicity; D-PBS; Dulbecco's phosphate-buffered saline; ECD; extracellular domain; FACS; fluorescence

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaques

Keywords: PBMCs; peripheral blood mononuclear cells; TNF-α; tumor necrosis factor α; IFN-γ; interferon γ; IM; intramuscular; IN; intranasal; O; oral; IT; intratracheal; IR; intrarectal; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCVI; antibody-depend

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders

Keywords: Epidermal growth factor-like module containing mucin-like hormone receptor 1; eosinophil; hypereosinophilic syndrome; mAb therapy; afucosylated antibody; eosinophilia; ADCC; Antibody-dependent cell-mediated cytotoxicity; AEC; Absolute eosinophil count;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Clinical evaluation of the endothelial tie-2 crossmatch in ABO compatible and ABO incompatible renal transplants

Keywords: ADCC; antibody dependent cell cytotoxicity; EC; endothelial cell; PEC; precursor endothelial cell; RTx; renal transplantation; IS; immunosuppression; MPA; mycophenolate acid; mTORi; mammalian target of rapamycin; PP; plasmapharesis; IVIg; intravenous immu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Cleavage of the interchain disulfide bonds in rituximab increases its affinity for FcγRIIIA

Keywords: RTX; rituximab; S-RTX; S-sulfonated rituximab; A-RTX; reduced and then alkylated rituximab; mAb; monoclonal antibody; ADCC; antibody-dependent cellular cytotoxicity; FcγR; Fcγ receptor; KHYG-1/FcγRIIIA; KHYG-1 cells stably expressing FcγRIIIA; SDS-P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluating the efficacy of rBmHATαc as a multivalent vaccine against lymphatic filariasis in experimental animals and optimizing the adjuvant formulation

Keywords: TLR-4 agonist; Vaccine; Adjuvant; Lymphatic filariasis; Alum; ADCC; Brugia malayi;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Poly(d,l)-lactide-co-glycolide (PLGA) microspheres as immunoadjuvant for Brugia malayi antigens

Keywords: Brugia malayi; PLGA microspheres; Immunoglobulins; Lymphocyte transformation test; Th1 cytokines; Nitric oxide; ADCC;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

A high throughput method for enrichment of natural killer cells and lymphocytes and assessment of in vitro cytotoxicity

Keywords: ADCC; Rapid high-throughput; Tetrameric antibody complexes; Magnetic cell separation; Chromium release; Calcein;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

ReviewManipulating T cell-mediated pathology: Targets and functions of monoclonal antibody immunotherapy

Keywords: Ab; antibody; ADCC; Antibody dependent cellular cytotoxicity; AICD; activation induced cell death; ATG; Anti-thymocyte globulin; ATGAM; Lymphocyte immune globulin; APC; Antigen presenting cells; CDC; Complement dependent cytotoxicity; CIA; Collagen induce

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

CR3 is the dominant phagocytotic complement receptor on human dendritic cells

Keywords: ADCC; antibody dependent cellular cytotoxicity; APC; antigen presenting cell; C3d(g); C3 d(g) fragment of C3; iC3b; inactivated complement C3b fragment; CR1; complement receptor type1; CR2; complement receptor type 2; CR3; complement receptor type 3; CR4;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Obstacles to ideal anti-HIV antibody-dependent cellular cytotoxicity responses

Keywords: HIV; ADCC; NK cells;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Optic neuritis in neuromyelitis optica

Keywords: NMO; Optic nerve; Aquaporin-4; Devic's disease; Neuroinflammation; ADCC; antibody-dependent cell-mediated cytotoxicity; AQP4; aquaporin-4; BBB; blood-brain barrier; CDC; complement-dependent cytotoxicity; CDCC; complement-dependent cell-mediated cytotox

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

A novel assay for detecting virus-specific antibodies triggering activation of Fcγ receptors

Keywords: ADCC; antibody-dependent cellular cytotoxicity; EBV; Epstein-Barr virus; ELISA; enzyme-linked immunosorbent assay; FcγR; Fcγ receptor; Fab-g; IgG Fab fragment; Fc-g; IgG Fc fragment; GAM; goat anti mouse antibody; HCMV; human cytomegalovirus; HSV; her

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

O-linked glucosylation of a therapeutic recombinant humanised monoclonal antibody produced in CHO cells

Keywords: rh-mAbX; recombinant humanised monoclonal antibody X; CHO; Chinese Hamster Ovary; HPAEC-PAD; High Performance Anion Exchange Chromatography-Pulsed Amperometric Detection; ADCC; Antibody-Dependent Cellular-Cytotoxicity; Lys-C; Endoproteinase Lys-C; ODS

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2013 سفارش ترجمه

Endogenous IL-8 acts as a CD16 co-activator for natural killer-mediated anti-CD20 B cell depletion in chronic lymphocytic leukemia

Keywords: CLL; NK; Anti-CD20 monoclonal antibodies; IL-8; ADCC;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A novel antibody-like TCRγδ-Ig fusion protein exhibits antitumor activity against human ovarian carcinoma

Keywords: TCR γδ; ADCC; Tumor-targeted immunotherapy; Xenograft model;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Impact of antibody quality and anamnestic response on viremia control post-challenge in a combined Tat/Env vaccine regimen in rhesus macaques

Keywords: HIV vaccine; HIV Tat; HIV Envelope; Rhesus macaque; SHIV challenge; ADCC

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Epistatic interactions between Fc (GM) and FcγR genes and the host control of human immunodeficiency virus replication

Keywords: GM allotypes; KM allotypes; FcγR; ADCC; HIV

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Correlation between CD16a binding and immuno effector functionality of an antigen specific immunoglobulin Fc fragment (Fcab)

Keywords: Antibody; Immunoglobulin; Fc fragment; Fc receptor binding; CD16a; CD64; ADCC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Development of an ELISA based bridging assay as a surrogate measure of ADCC

Keywords: ADCC; Surrogate; Bridging; ELISA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Low level of FcγRIII expression on murine natural killer cells

Keywords: Immunoglobulin G; NK cells; Fc receptors; Macrophage; Monocytes; ADCC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanism of action of therapeutic monoclonal antibodies: Promises and pitfalls of in vitro and in vivo assays

Keywords: Antibody; Complement; ADCC; Phagocytosis; Cell death;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

An afucosylated anti-CD20 monoclonal antibody with greater antibody-dependent cellular cytotoxicity and B-cell depletion and lower complement-dependent cytotoxicity than rituximab

Keywords: CD20; Monoclonal antibody; ADCC; CDC; Afucosylated;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast

Keywords: IgG1; immunoglobulin G class 1; Fcab; antigen binding Fc protein; Fc-wt; recombinant wild-type Fc protein; scTCR; single-chain T-cell receptor; MHC; major histocompatibility complex; CDC; complement dependent cytotoxicity; ADCC; antibody dependent cell-me

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Monoclonal Antibodies for Therapeutic Use: Specific Characteristics of Clinical Development, Evaluation by the Agencies, and Long-term Monitoring of Safety

Keywords: monoclonal antibodies; clinical trials, phase I; clinical trials, phase II; clinical trials, phase IV; ADCC; antibody dependent cellular cytotoxicity; (ex-)Afssaps; ex-Agence française de sécurité sanitaire des produits de santé (at present french Nat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Anticorps monoclonaux à usage thérapeutique : spécificités du développement clinique, évaluation par les agences, suivi de la tolérance à long terme

Keywords: anticorps monoclonaux; essais cliniques, phase I; essais cliniques, phase II; essais cliniques, phase IV; AcMo; anticorps monoclonaux; ADCC; antibody dependent cellular cytotoxicity; Afssaps; Agence française de sécurité sanitaire des produits de santÃ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41

Keywords: HIV; VLP; Neutralizing antibodies; gp41; ADCC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Role of monocytes in mediating HIV-specific antibody-dependent cellular cytotoxicity

Keywords: HIV-1; human immunodeficiency virus type 1; ADCC; antibody-dependent cellular cytotoxicity; RFACCC assay; rapid fluorometric antibody-dependent cellular cytotoxicity assay; CFSE; Carboxyfluorescein succinimidyl ester; Antibody-dependent cellular cytotoxic

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Neuromyelitis optica: Aquaporin-4 based pathogenesis mechanisms and new therapies

Keywords: ADCC; antibody-dependent cellular cytotoxicity; AQP; aquaporin; AQP4; aquaporin-4; AQP4-IgG; anti-AQP4 immunoglobulin NMO autoantibody; BN-PAGE; blue-native polyacrylamide gel electrophoresis; CDC; complement-dependent cytotoxicity; CNS; central nervous s

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Perspectives des thérapies ciblées dans le cancer du sein métastatique

Keywords: thérapie ciblée; cancer du sein métastatique; HER-2; anti-angiogénèse; étude clinique; targeted therapy; metatstatic breast cancer; HER-2; anti-agiogenesis; clinical trial; ADCC; cytotoxicité à médiation cellulaire anticorps-dépendante; Akt; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Synergistic cytotoxicity of ex vivo expanded natural killer cells in combination with monoclonal antibody drugs against cancer cells

Keywords: ADCC; antibody-dependent cellular cytotoxicity; E/T ratio; effector-to-target ratio; FcγR; Fcγ receptor; mAb; monoclonal antibody; NK cell; natural killer cell; PBMC; peripheral blood mononuclear cell; NK cell; ADCC; Monoclonal antibody drug; Cancer ste

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Antibody-dependent cell-mediated cytotoxicity is induced by a single-chain Fv-protein III fusion in the presence of a rabbit anti-protein III polyclonal antibody

Keywords: Human monoclonal antibodies; ADCC; Phage display; Protein III; Cancer antigen; Rabbit IgG;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Target-induced natural killer cell loss as a measure of NK cell responses

Keywords: Human NK cells; Cytotoxicity; CD107a; ADCC; Rituximab

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Pol as a target for antibody dependent cellular cytotoxicity responses in HIV-1 infection

Keywords: HIV; ADCC; Pol; Gag; Env; NK cell; IFNg; CD107a;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of antibody effector function

Keywords: Antibody; Fc; Effector function; ADCC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

La polyarthrite rhumatoïde: un vieux système dans un nouveau concept

Keywords: Polyarthrite rhumatoïde; anti-CCP; HLA DR; TH17; T régulateur; CD20; Rheumatoid arthritis; anti-CCP; HLA DR; TH17; T regulator; CD20; ADCC; cytotoxicité dépendante des anticorps; AP1; activator protein 1; APRIL; a proliferation-inducing ligand; BAFF;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه