دانلود مقالات ISI درباره آمیلوئید β + ترجمه فارسی

Research articleKrüppel-like factor 4 regulates amyloid-β (Aβ)-induced neuroinflammation in Alzheimer's disease

Keywords: آمیلوئید β; AD; Alzheimer's disease; Aβ; amyloid-β; Klf 4; Krüppel-like factor 4; TNF-α; tumor necrosis factor-a; IL-1β; interleukin-1β; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; CNS; central neural system; LPS; lipopolysaccharide; HFIP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperEffects of phenothiazine-structured compounds on APP processing in Alzheimer's disease cellular model

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β peptide; Cholinesterase inhibitor; Phenothiazine; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; ACh; acetylcholine; AChE; acetylcholinesterase; BACE1; β-site APP-cleaving enzyme 1; BChE; butyryl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

INT131 increases dendritic arborization and protects against Aβ toxicity by inducing mitochondrial changes in hippocampal neurons

Keywords: آمیلوئید β; SPPARM; PPARγ; Amyloid-β; Hippocampal neurons; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Seizure susceptibility in the APP/PS1 mouse model of Alzheimer's disease and relationship with amyloid β plaques

Keywords: آمیلوئید β; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; DSP4; N-(2-chloroethyl)-N-ethylbromo-benzylamine; GABA; γ-aminobutyric acid; PTZ; pentylenetetrazole; WT; wild-type; Epileptiform-like discharges; Aβ plaques; EEG; Pentylenetetr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Antibodies against the C-terminus of α-synuclein modulate its fibrillation

Keywords: آمیلوئید β; Aβ; amyloid-β; aSN; α-synuclein; DOPG; dioleoyl-phosphatidylglycerol; EGCG; Epigallocatechin gallate; ELISA; enzyme-linked immunosorbent assay; LUV; large unilamellar vesicles; mAbs; monoclonal antibodies; NAC; non-Amyloid beta component; NC; negative

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ

Keywords: آمیلوئید β; Amyloid-β; γ-secretase; DAPT; Duolink; Neurons; Oligomers;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Featured ArticleNeuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome

Keywords: آمیلوئید β; Intellectual disability; Down syndrome; Alzheimer's disease; Blood biomarkers; Neuronal exosomes; Hyperphosphorylated tau; Amyloid-β;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome

Keywords: آمیلوئید β; Alzheimer's disease; Dementia; Down syndrome; Amyloid-β; PiB; Mild cognitive impairment;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Berberine modulates amyloid-β peptide generation by activating AMP-activated protein kinase

Keywords: آمیلوئید β; Alzheimer's disease; Berberine; AMP-activated protein kinase; Amyloid-β; β-site APP cleaving enzyme-1; AD; Alzheimer's disease; Aβ; Amyloid-β; APP; Amyloid precursor protein; AMPK; AMP-activated protein kinase; BACE1; β-site APP cleaving enzyme-1; β

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportPossible role of endothelin receptor against hyperhomocysteinemia and β-amyloid induced AD type of vascular dementia in rats

Keywords: آمیلوئید β; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β; BBB; blood brain barrier; BSA; bovine serum albumin; CBF; cerebral blood flow; ECE; endothelin converting enzyme; ELT; escape latency time; eNOS; endothelial nitric oxide synthase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticlePharmacophore based 3D-QSAR modeling, virtual screening and docking for identification of potential inhibitors of β-secretase

Keywords: آمیلوئید β; BACE1; β-secretase; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood brain barrier; PDB; protein data bank; rmsd; root mean square deviation; IC50; inhibitory concentration; β-secretase; Alzheimer's disease; Pharmacophore; Virtual screening; Doc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Amyloid β peptide promotes lysosomal degradation of clusterin via sortilin in hippocampal primary neurons

Keywords: آمیلوئید β; Amyloid-β; Clusterin; Sortilin; Lysosomal degradation; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperTreadmill exercise decreases amyloid-β burden possibly via activation of SIRT-1 signaling in a mouse model of Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β; Treadmill exercise; Sirtuin-1; Non-amyloidogenic pathway;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Oleocanthal ameliorates amyloid-β oligomers' toxicity on astrocytes and neuronal cells: In vitro studies

Keywords: آمیلوئید β; ABCA1; ATP-binding cassette transporter-A1; ACM; astrocyte-conditioned media; AD; Alzheimer's disease; ApoE; apolipoprotein E; APP; amyloid precursor protein; Aβ; amyloid-β; Aβm; Aβ monomer; Aβo; Aβ oligomers; BBB; blood-brain barrier; BSA; bovi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Rapamycin suppresses Aβ25-35- or LPS-induced neuronal inflammation via modulation of NF-κB signaling

Keywords: آمیلوئید β; AD; Alzheimer's disease; Aβ; amyloid-β; BSA; bovine serum albumin; DMSO; dimethyl sulphoxide; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharides; mTOR; mammalian target of rapamycin; NF-κB; nuclear factor kappa B; PD; Parkinson's disea

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Xuefu Zhuyu decoction ameliorates obesity, hepatic steatosis, neuroinflammation, amyloid deposition and cognition impairment in metabolically stressed APPswe/PS1dE9 mice

Keywords: آمیلوئید β; Aβ; amyloid-β;; AD; Alzheimer's disease; ADL; activity of daily living; ANOVA; analysis of variant; APP; amyloid precursor protein; AICD; APP intracellular domain; APP/PS1; APPswe/PS1ΔE9; AUC; area under the curve; BBB; blood-brain barrier; BSB; 1-brom

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Featured ArticleAmyloid tracers binding sites in autosomal dominant and sporadic Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β; Autosomal dominant Alzheimer's disease; Positron emission tomography; Resveratrol; Pittsburgh compound B; AZD2184; Florbetaben;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Peptides from sesame cake reduce oxidative stress and amyloid-β-induced toxicity by upregulation of SKN-1 in a transgenic Caenorhabditis elegans model of Alzheimer's disease

Keywords: آمیلوئید β; C. elegans; Caenorhabditis elegans; PSC; peptides from sesame cake; AD; Alzheimer's disease; Aβ; amyloid-β; FUdR; 5-fluoro-2′-deoxyuridine; E. coli; Escherichia coli; DCF-DA; dichlorofluorescin diacetate; ROS; reactive oxygen species; qRT-PCR; quant

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Emerging structural details of transient amyloid-β oligomers suggest designs for effective small molecule modulators

Keywords: آمیلوئید β; Amyloid-β; Alzheimer's disease; Protein aggregation; Amyloid oligomers;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Review articleBrain interference: Revisiting the role of IFNγ in the central nervous system

Keywords: آمیلوئید β; AMPA; amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APC; antigen-presenting cell; APP; amyloid processing protein; Aβ; amyloid-β; BBB; blood-brain barrier; BCG; bacillus Calmette-Guérin; BCSFB; blood-cerebrospinal fluid barrier; BDNF; brain-der

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy in neuroinflammatory diseases

Keywords: آمیلوئید β; Aβ; amyloid-β; Ab; antibody; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APC; antigen-presenting cell; APP; amyloid precursor protein; ATG; autophagy-related; ATG1/ULK; unc-51 like autophagy activating kinase-1; ATG6/Beclin-1; Bcl-2 int

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease

Keywords: آمیلوئید β; Nicotinamide mononucleotide; Alzheimer disease; JNK activation; Amyloid-β;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Integrated late onset Alzheimer's disease (LOAD) susceptibility genes: Cholesterol metabolism and trafficking perspectives

Keywords: آمیلوئید β; Aβ; Amyloid-β; AD; Alzheimer's disease; ApoE; Apolipoprotein E; APP; Amyloid precursor protein; BBB; Blood brain barrier; CLU; Clusterin; CNS; Central nervous system; CSF; Cerebrospinal fluid; DMN; Default mode network; EOAD; Early onset Alzheimer's dis

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of post-translational modifications of Aβ peptide in platelet membranes from patients with cerebral amyloid angiopathy

Keywords: آمیلوئید β; CAA; cerebral amyloid angiopathy; AD; Alzheimer's disease; ThT; thioflavin T; PTMs; post-translational modifications; Aβ; amyloid-β; UPLC/ESI-Q-TOF/MS; ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectro

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

N-glycan and Alzheimer's disease

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer's disease; APOE; apolipoprotein E; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme-1; DAP12; DNAX-activating protein of 12 kD; GnT-III; N-acetylglucosaminyltransferase-III; NFT; neurofibrillary tangle; PS

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Berberine; Autophagy; Amyloid-β; BACE1; Spatial cognitive deficits;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Alzheimer's disease markers in the aged sheep (Ovis aries)

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β; Sheep Ovis aries; Plaques; Tangles; Animal model;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Lipid membranes catalyse the fibril formation of the amyloid-β (1-42) peptide through lipid-fibril interactions that reinforce secondary pathways

Keywords: آمیلوئید β; Alzheimer's Disease; amyloid-β; aggregation kinetics, lipid vesicles, fibril-lipid interaction; DOPC;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted delivery of rosmarinic acid across the blood-brain barrier for neuronal rescue using polyacrylamide-chitosan-poly(lactide-co-glycolide) nanoparticles with surface cross-reacting material 197 and apolipoprotein E

Keywords: آمیلوئید β; Alzheimer's disease; Neuron; Amyloid-β; SK-N-MC cell; RWA264.7 cell; Pharmacotherapy; Nanocarrier;

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment

Keywords: آمیلوئید β; Alzheimer's disease; 2-arylethenyl-N-methylquinolinium derivatives; Aβ aggregation; Cholinesterase inhibition; Neuroprotection; AAPH; 2, 2'-azobis (2-methylpropionamidine) dihydrochloride; Aβ; amyloid-β; AChE; acetylcholinesterase; AD; Alzheimer's di

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders

Keywords: آمیلوئید β; 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2017 سفارش ترجمه

Amyloid β19-20 peptide in vitro self-assembled into architectural wires

Keywords: آمیلوئید β; Alzheimer disease; Amyloid-β; Peptide wires; Self-assembly;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHCA; dihydrocaffeic acid; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; Gly; glycine; HBTU; O

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Transfer of three transcription factors via a lentiviral vector ameliorates spatial learning and memory impairment in a mouse model of Alzheimer's disease

Keywords: آمیلوئید β; AD; Alzheimer's disease; LV; Lentiviral vector; Ascl1, Brn2 and Ngn2; ABN gene; Ascl1; Achaete-scute complex homolog 1; Brn2; POU class 3 homeobox 2; Ngn2; Neurogenin 2; Aβ; Amyloid-β; BDNF; Brain-derived neurotrophic factor; Nrf2; Nuclear factor-E2-rel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Detection of amyloid-β fibrils using the DNA-intercalating dye YOYO-1: Binding mode and fibril formation kinetics

Keywords: آمیلوئید β; YOYO-1; Thioflavin-T; Amyloid fibril; Amyloid-β; Fluorescence; Linear dichroism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportCerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele

Keywords: آمیلوئید β; Apolipoprotein ε4; High density lipoproteins; Amyloid-β; Aggregation; Thioflavin T; Neurofibrillary tangles; Kinetics; Inhibition; Cholesterol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperMagnetic resonance T2 relaxation time at 7 Tesla associated with amyloid β pathology and age in a double-transgenic mouse model of Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's; disease; Double transgenic mice; Amyloid-β; MRI; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Physical activity; Exercise training; Amyloid-β; Amyloid-β clearance proteins; Heat shock protein 70;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Solution NMR structure and inhibitory effect against amyloid-β fibrillation of Humanin containing a d-isomerized serine residue

Keywords: آمیلوئید β; Humanin; d-isomerization; NMR spectroscopy; Alzheimer's disease; Amyloid-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Emerging roles of the acute phase protein pentraxin-3 during central nervous system disorders

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer's disease; APPs; acute phase proteins; APR; acute phase response; BBB; blood-brain barrier; C1q; complement component 1q; CNS; central nervous system; CRP; C-reactive protein; CSF; cerebral spinal fluid; DCs; dendritic cel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

White matter hyperintensities, cerebrospinal amyloid-β and dementia in Parkinson's disease

Keywords: آمیلوئید β; Parkinson's disease; Dementia; White matter hyperintensities; Cerebrospinal fluid; Amyloid-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Quantification of molecular interactions between ApoE, amyloid-beta (Aβ) and laminin: Relevance to accumulation of Aβ in Alzheimer's disease

Keywords: آمیلوئید β; Apolipoprotein E; Perivascular clearance pathways; Laminin; Atomic force microscopy; Amyloid-β; Cerebral amyloid angiopathy; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Divergent Network Patterns of Amyloid-β Deposition in Logopenic and Amnestic Alzheimer's Disease Presentations

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β; Apolipoprotein E ε4; Complex network analysis; Logopenic variant of primary progressive aphasia; Pittsburgh Compound B positron emission tomography (PiB-PET);

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Peripherally administered sera antibodies recognizing amyloid-β oligomers mitigate Alzheimer's disease-like pathology and cognitive decline in aged 3× Tg-AD mice

Keywords: آمیلوئید β; Alzheimer's disease; Immunotherapy; Passive immunization; Amyloid-β; Tau;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds

Keywords: آمیلوئید β; Amyloid-β; Alzheimer's disease; Molecular imaging; Contrast agent;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The new β amyloid-derived peptide Aβ1-6A2V-TAT(D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity

Keywords: آمیلوئید β; (AD); Alzheimer's disease; (Aβ); amyloid-β; (APP); amyloid precursor protein; (A673V); alanine-to-valine substitution at codon 673; (AβA2V); A-V mutated Aβ; (WT); wild-type; (Aβ1-6A2V); peptide homologous to residues 1-6 of AβA2V; [Aβ1-6A2V(D

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Preservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotype

Keywords: آمیلوئید β; Presenilin 1 mutation; Amyloid-β; Oxidative stress; Apoptosis; MAP kinase signaling; Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Hippocampal neurogenesis in the APP/PS1/nestin-GFP triple transgenic mouse model of Alzheimer's disease

Keywords: آمیلوئید β; 2xTgAD; APP/PS1 double transgenic mice; 3xTgAD; APP/PS1/nestin-GFP triple transgenic mice; Aβ; amyloid-β; AD; Alzheimer's disease; ANOVA; analysis of variance; APP; amyloid precursor protein; BrdU; 5-bromo-2-deoxyuridine; DCX; doublecortin; DG; dentat

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport

Keywords: آمیلوئید β; 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood-brain barrier; bEnd.3; mouse brain microvascular endothelial cell lines; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme-linked immunosorbent assay

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Neuronal expression of ILEI/FAM3C and its reduction in Alzheimer's disease

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer's disease; APP; amyloid-β precursor protein; CSF; cerebrospinal fluid; EMT; epithelial-to-mesenchymal transition; FAM3; family with sequence similarity 3; ILEI; interleukin-like EMT inducer; TGF-β; transforming growth fa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه