دانلود مقالات ISI درباره آمیلوئید β + ترجمه فارسی

Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer's disease; ALA; α-linolenic acid; ANOVA; analyses of variance; APP; amyloid-β precursor protein; ATF4; activating transcription factor 4; BACE1; β-site APP-cleaving enzyme 1; BSA; bovine serum albumin; CAA; cerebral amy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload

Keywords: آمیلوئید β; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β; BBB; blood-brain barrier; DFO; deferoxamine; DFP; deferiprone; DFX; deferasirox; Drp1; dynamin-related protein 1; HFe; high-iron diet; Mfn2; mitofusin2; NAC; n-acetyl cysteine;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Reelin-immunoreactive neurons in entorhinal cortex layer II selectively express intracellular amyloid in early Alzheimer's disease

Keywords: آمیلوئید β; Neurodegeneration; Neuropathology; Amyloid-β; Hippocampal formation; Parahippocampal region;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Chemical modifications of amyloid-β(1-42) have a significant impact on the repertoire of brain amyloid-β(1-42) binding proteins

Keywords: آمیلوئید β; Amyloid-β; Amyloid-β binding proteins; Proteomic profiling; Mouse brain; IsoAsp7-Aβ; pSer8-Aβ;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Full length articleGold nanoparticle-capped mesoporous silica-based H2O2-responsive controlled release system for Alzheimer's disease treatment

Keywords: آمیلوئید β; Alzheimer's disease; Metal ions; Amyloid-β; Controlled release system; Mesoporous silica nanoparticle;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Quercetin attenuates tau hyperphosphorylation and improves cognitive disorder via suppression of ER stress in a manner dependent on AMPK pathway

Keywords: آمیلوئید β; AMPK; ER stress; NLRP3 inflammasome; Quercetin; Quercetin-3-O-glucuronide; Tau phosphorylation; Compound C (PubChem CID: 11524144); Metformin (PubChem CID: 14219); Okadaic acid (PubChem CID: 446512); Quercetin (PubChem CID: 5280343); Quercetin-3-O-glucuro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer's disease; ANS; 8-anilinonapthalene-1-sulfonic acid; CAA; cerebral amyloid angiopathy; CAPS; 3-cyclohexamino-1-propanesulfonic acid; CD; circular dichroism; CNS; central nervous system; cyt c; cytochrome c; DCFDA; 2′,7′-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival

Keywords: آمیلوئید β; Heat shock protein; Retina; Ganglion cells; Optic nerve; Glaucoma; Neuroprotection; 17-AAG; 17-allylamino-17-demethoxygeldanamycin; AAV; adeno-associated virus; AD; Alzheimer's disease; Aβ; amyloid-β; ER; endoplasmic reticulum; GCL; ganglion cell layer;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease

Keywords: آمیلوئید β; Estradiol; Brain-selective prodrug; Alzheimer's disease; Transgenic mice; Amyloid-β; Radial arm water maze;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy

Keywords: آمیلوئید β; Amyloid-β; Leptomeningeal arteries; Perivascular drainage; Basement membranes; Cerebral amyloid angiopathy;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Role of P-glycoprotein in mediating rivastigmine effect on amyloid-β brain load and related pathology in Alzheimer's disease mouse model

Keywords: آمیلوئید β; ABCA1; ATP-binding cassette sub-family A, member 1; APP; amyloid precursor protein; ACh; acetylcholine; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood-brain barrier; BSA; bovine serum albumin; ChEIs; Cholinesterase inhibitors, ELISA, enzyme-linked

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Cerebral amyloid-β accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies

Keywords: آمیلوئید β; Traumatic brain injury; TBI; Amyloid-β; Alzheimer's disease; Animal models; dementia;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity

Keywords: آمیلوئید β; Hydroxybenzoyl-pyridones; Tacrine; Anti-neurodegeneratives; Anti-AChE activity; Anti-oxidant activity; Metal chelation; Aβ; amyloid-β; ACh; acetylcholine; AChE; acetylcholinesterase; AChI; acetylthiocholine iodide; AD; Alzheimer's disease; BuChE; butyry

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Tau; Amyloid-β; Brain-derived neurotrophic factor; Tauopathy; Transgenic mice;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2016 سفارش ترجمه

Amyloid-β peptide increases cell surface localization of α7 ACh receptor to protect neurons from amyloid β-induced damage

Keywords: آمیلوئید β; Amyloid-β; α7 ACh receptor; Translocation; Protection; Neuronal death;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide

Keywords: آمیلوئید β; Amyloid-β; Aβ oligomer; Amyloid fibril; tyrosine fluorescence; Acrylamide quenching;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by Aβ(1-40) and Aβ(1-42)

Keywords: آمیلوئید β; Amyloid-β; Amyloid fibrils; Alzheimer's disease; Thioflavin-T; Amyloid dye; Fluorescence lifetime;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Live imaging reveals a new role for the sigma-1 (σ1) receptor in allowing microglia to leave brain injuries

Keywords: آمیلوئید β; Aβ; amyloid-β; IL; interleukin; TNF; tumor necrosis factor; σ Receptor; Fluorescence microscopy; Microglia; Optical imaging;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma and cerebrospinal fluid amyloid-β levels in late-life depression: A systematic review and meta-analysis

Keywords: آمیلوئید β; Late-life depression; Dementia; Amyloid-β; Plasma; Cerebrospinal fluid; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease

Keywords: آمیلوئید β; Pyroglutamate-modified Aβ; Amyloid-β; Alzheimer's disease; Posterior cingulate cortex; MCI; Episodic memory;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

CREB expression mediates amyloid β-induced basal BDNF downregulation

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β; Brain-derived neurotrophic factor; cAMP response element binding protein; Human neuroblastoma SH-SY5Y; mRNA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Donepezil attenuates Aβ-associated mitochondrial dysfunction and reduces mitochondrial Aβ accumulation in vivo and in vitro

Keywords: آمیلوئید β; Alzheimer's disease; Donepezil; Amyloid-β; Oligomer; Mitochondrial dysfunction;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloid-β precursor protein: Multiple fragments, numerous transport routes and mechanisms

Keywords: آمیلوئید β; APP; Amyloid-β Precursor Protein; AD; Alzheimer׳s disease; Aβ; Amyloid-β; ER; endoplasmic reticulum; ERGIC; ER-Golgi Intermediate Compartment; TGN; trans-Golgi network; AICD; APP Intracellular Domain; PTB; phosphotyrosine binding; JIP-1; JNK-interacti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A novel method for expression and purification of authentic amyloid-β with and without 15N labels

Keywords: آمیلوئید β; Amyloid-β; Alzheimer's disease; His-tag; TEV protease; Partial refolding; NMR; Metal ions;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of growth hormone-releasing hormone on sleep and brain interstitial fluid amyloid-β in an APP transgenic mouse model

Keywords: آمیلوئید β; Alzheimer's disease; Amyloid-β; Growth hormone-releasing hormone; Sleep;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Quercetin reduces eIF2α phosphorylation by GADD34 induction

Keywords: آمیلوئید β; GADD34; ATF4; Quercetin; Amyloid-β; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Accumulation and age-related elevation of amyloid-β within basal forebrain cholinergic neurons in the rhesus monkey

Keywords: آمیلوئید β; Aβ; amyloid-β; Aβ1-40; 1-40 amino acid isoform of Aβ; Aβ1-42; 1-42 amino acid isoform of Aβ; AD; Alzheimer's disease; APP; amyloid precursor protein; BFCN; basal forebrain cholinergic neurons; Ca2 +; calcium; Ch4; cholinergic cell group 4;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice

Keywords: آمیلوئید β; Alzheimer's disease; amyloid-β; APP/PS1 transgenic mice; curcumin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model

Keywords: آمیلوئید β; Alzheimer's disease; Geniposide; APP/PS1 transgenic mice; Amyloid-β; Receptor for advanced glycation end products; AD; Alzheimer's disease; APP/PS1 mice; mPrP-APPswe/PS1dE9 AD transgenic mice; Aβ; Amyloid-beta peptide; BACE1; β-site APP cleaving enzyme

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Herpes simplex virus type 2 infection induces AD-like neurodegeneration markers in human neuroblastoma cells

Keywords: آمیلوئید β; HSV-2 infection; Tau; Amyloid-β; Autophagy; Neurodegeneration; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice

Keywords: آمیلوئید β; Amyloid-β; Alzheimer treatment; Nanoparticles; APP/PS1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice

Keywords: آمیلوئید β; Amyloid-β; Alzheimer's disease; Cell differentiation; Growth factor; BACE1; Inflammation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer's disease

Keywords: آمیلوئید β; AD; Alzheimer's disease; ANOVA; analysis of variance; Aβ; amyloid-β; BBB; blood-brain barrier; EDTA; ethylenediaminetetraacetic acid; ET; endothelin; MAPK; mitogen-activated protein kinase; MWM; Morris water maze; NGF; nerve growth factor; PBS; phos

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Research reportEndomorphin-1 attenuates Aβ42 induced impairment of novel object and object location recognition tasks in mice

Keywords: آمیلوئید β; Endomorphin-1; Amyloid-β; Alzheimer׳s disease; Recognition memory;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Emerging roles of the γ-secretase-notch axis in inflammation

Keywords: آمیلوئید β; Inflammation; Notch; γ-Secretase; Inflammatory diseases; Stroke; Aβ; amyloid-β; AD; Alzheimer's disease; AICD; APP intracellular domain; ALPS; autoimmune lymphoproliferative syndrome; Aph-1; anterior pharynx-defective 1; ApoE; apolipoprotein E; APP; am

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective effect of memantine on the retinal ganglion cells of APPswe/PS1ΔE9 mice and its immunomodulatory mechanisms

Keywords: آمیلوئید β; Alzheimer's disease; Memantine; Retinal ganglion cell; Müller cell; Microglia; Aβ; amyloid-β; AD; Alzheimer's disease; BSA; bovine serum albumin; ChAT; choline acetyl transferase; dtg; double transgenic; ERK1/2; extracellular signal-regulated protein k

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Aβ induces PUMA activation: a new mechanism for Aβ-mediated neuronal apoptosis

Keywords: آمیلوئید β; Amyloid-β; Apoptosis; PUMA; FOXO3a; ARC;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset

Keywords: آمیلوئید β; Amyloid-β; Amyloid precursor protein; APP/PS1 mice; Glycogen synthase kinase β; Gliosis; Tau; TUDCA;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Nerve growth factor; Choline acetyltransferase; Acetyl cholinesterase; tau; Amyloid-β; Nicotine receptors; PET; MRI;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation

Keywords: آمیلوئید β; AChEIs; acetylcholinesterase inhibitors; AD; Alzheimer's disease; ANOVA; analysis of variance; APP; amyloid precursor protein; Aβ; amyloid-β; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HRP; horseradish p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportGlio-vascular changes during ageing in wild-type and Alzheimer׳s disease-like APP/PS1 mice

Keywords: آمیلوئید β; Aβ; amyloid-β; AD; Alzheimer׳s disease; APP; amyloid precursor protein; BBB; blood-brain barrier; CD31; cluster of differentiation 31; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding adapter molecule 1; PDGFR-β; platelet-derived

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer's disease

Keywords: آمیلوئید β; Alzheimer's disease; Mitochondrial fragmentation; GSK3β; Drp1; Amyloid-β; Neuronal apoptosis; TAT-like polypeptide; APP/PS1 transgenic mice; Learning and memory;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death

Keywords: آمیلوئید β; 24S-OHC; 24(S)-hydroxycholesterol; 5,6-epoxyC; cholesterol-5,6-epoxide; 7-OOHC; 7-hydroperoxycholesterol; 7-OHC; 7-hydroxycholesterol; Aβ; amyloid-β; ACAT1; acyl-CoA:cholesterol acyltransferase 1; AD; Alzheimer disease; APP; amyloid precursor protein; C

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of oxidative stress in the brain of a transgenic mouse model of Alzheimer disease by in vivo electron paramagnetic resonance imaging

Keywords: آمیلوئید β; Alzheimer disease; Hippocampus; EPR; Imaging; ROS; Redox status; Oxidative stress; Microglia; Astrocytes; Amyloid-β; Free radicals;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه

(−)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer's therapy

Keywords: آمیلوئید β; AD; Alzheimer's disease; Aβ; amyloid-β; ACh; acetylcholine; AChE; acetylcholinesterase; AChEIs; acetylcholinesterase inhibitors; BChE; butyrylcholinesterase; BBB; blood-brain barrier; CAS; catalytic anionic site; ChEs; cholinesterases; CCK-8; cell c

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2015 سفارش ترجمه

Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice

Keywords: آمیلوئید β; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid-β precursor protein; BBB; blood-brain barrier; BCI; brain clearance index; CAA; cerebral amyloid angiopathy; DEA; diethylamine; EVOO; extra-virgin olive oil; FA; formic acid; IDE; insulin degradi

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2015 سفارش ترجمه

APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice

Keywords: آمیلوئید β; Alzheimer's disease; Estrogen; Amyloid-β; APOE; Soluble Aβ; AD transgenic mouse model; Aβ; amyloid-β; apoE; apolipoprotein E; AD; Alzheimer's disease; ET; estrogen therapy; FAD; familial AD; Thio-S; thioflavin S; HRT; hormone replacement therapy; OVX;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Short ReportCerebrospinal fluid BACE1 activity and markers of amyloid precursor protein metabolism and axonal degeneration in Alzheimer's disease

Keywords: آمیلوئید β; Biomarker; Dementia; Mild cognitive impairment; Diagnosis; Prognosis; Amyloid precursor protein; Amyloid-β; Tau; Correlation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Pretreatment with antiasthmatic drug ibudilast ameliorates Aβ1-42-induced memory impairment and neurotoxicity in mice

Keywords: آمیلوئید β; Ibudilast; Amyloid-β; Memory; Neurotoxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Metallothionein-III increases ADAM10 activity in association with furin, PC7, and PKCα during non-amyloidogenic processing

Keywords: آمیلوئید β; APP; amyloid precursor protein; MT-III; metallothionein-III; sAPPα; soluble APPα; AD; Alzheimer's disease; Aβ; amyloid-β; PC7; proprotein convertase7; PKC; protein kinase C; ADAM10; A-disintegrin and metalloproteinase 10; TGN; trans-Golgi network; T

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه