دانلود مقالات ISI درباره عوامل ضد سرطان + ترجمه فارسی

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

Keywords: عوامل ضد سرطان; Anticancer agents; Histone deacetylase inhibitors; 3-Aroylindoles; Tubulin polymerization inhibition;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Insights into the pharmacology of new heterocycles embedded with oxopyrrolidine rings: DNA binding, molecular docking, and anticancer studies

Keywords: عوامل ضد سرطان; Design of heterocycles; Oxopyrrolidine rings; Anticancer agents; Pharmacological evaluation; DNA binding and docking studies;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms

Keywords: عوامل ضد سرطان; Anticancer agents; Histone deacetylase inhibitors;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors

Keywords: عوامل ضد سرطان; Anticancer agents; 2-Aryl-4-(4′-hydroxyphenyl)-5H-indeno[1,2-b]pyridine; Antiproliferative activity; Docking study; Dual topoisomerase I and II inhibitors;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and tumor cell growth inhibitory activity of 3-nitro-2H-cheromene derivatives as histone deacetylaes inhibitors

Keywords: عوامل ضد سرطان; HDACs; HDAC inhibitors; 3-Nitro-2H-chromenes; Coumarins; Anticancer agents; Zinc-dependent hydrolases; Isoform selective;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Facile synthesis of novel substituted aryl-thiazole (SAT) analogs via one-pot multi-component reaction as potent cytotoxic agents against cancer cell lines

Keywords: عوامل ضد سرطان; Thiazole; Characterization; Anticancer agents; (MCF7, MDA-MB-231); (HCT-116); (HeLa); Cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors

Keywords: عوامل ضد سرطان; Leucyl-tRNA synthetase; LRS; mTORC1 inhibitor; Anticancer agents;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?

Keywords: عوامل ضد سرطان; G-triplex; G-quadruplex; Ligand; Anticancer agents; Drug discovery;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

In vitro targeting of colon cancer cells using spiropyrazoline oxindoles

Keywords: عوامل ضد سرطان; Spirooxindoles; Pyrazoline; Cytotoxicity; Anticancer agents; Colorectal cancer;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and characterization of novel quinacrine analogs that preferentially kill cancer over non-cancer cells through the down-regulation of Bcl-2 and up-regulation of Bax and Bad

Keywords: عوامل ضد سرطان; Quinacrine; 9-aminoacridine; Thiazolidin-4-one; Hybrid approach; Anticancer agents; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes

Keywords: عوامل ضد سرطان; G-quadruplex; Virtual screening; Anticancer agents; Drug discovery;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

An efficient green synthesis of 2-arylbenzothiazole analogues as potent antibacterial and anticancer agents

Keywords: عوامل ضد سرطان; 2-Arylbenzothiazole; Green chemistry; Amberlite IR-120; Antibacterial agents; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines

Keywords: عوامل ضد سرطان; 2,4-Diphenyl-5H-indeno[1,2-b]pyridine analog; Anticancer agents; Breast cancer; Cytotoxicity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents

Keywords: عوامل ضد سرطان; Anticancer agents; Tubulin inhibitor; Intra-molecular hydrogen bonding; Colchicine binding site; RYRVKOAZGRXPLW-UHFFFAOYSA-N; MHEDZIYFQFWRMO-UHFFFAOYSA-N; QBNMSKFVSPKNSV-UHFFFAOYSA-N; YMIQVUIBWOJUPW-UHFFFAOYSA-N; HKFGTRWTMQYJOL-UHFFFAOYSA-N; ZBJRJZBGMBEVH

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

EPR spectroscopic characterization of a monomeric PtIII species produced via electrochemical oxidation of the anticancer compound trans-[PtII{(p-HC6F4)NCH2CH2NEt2}Cl(py)]

Keywords: عوامل ضد سرطان; Anticancer agents; Electrochemical generation of monomeric PtIII species; EPR spectroscopy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

New alicyclic thiosemicarbazone chelated zinc(II) antitumor complexes: Interactions with DNA/protein, nuclease activity and inhibition of topoisomerase-I

Keywords: عوامل ضد سرطان; Zinc(II) thiosemicarbazone complexes; DNA/protein binding; Chemical nucleases; Topoisomerase inhibitor; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

A comparative study on the interactions of human copper chaperone Cox17 with anticancer organoruthenium(II) complexes and cisplatin by mass spectrometry

Keywords: عوامل ضد سرطان; Organoruthenium complexes; Cisplatin; Cox17; Anticancer agents; LC-ESI-MS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs

Keywords: عوامل ضد سرطان; Anticancer agents; Pretubulysin; Deacetoxytubuvaline; Scalable synthesis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

CDODA-Me decreases specificity protein transcription factors and induces apoptosis in bladder cancer cells through induction of reactive oxygen species

Keywords: عوامل ضد سرطان; Bladder cancer; Specificity protein (Sp) transcription factors; Reactive oxygen species (ROS); Antioxidants; Targeted therapy; Anticancer agents;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

QSAR studies on pyrazole-4-carboxamide derivatives as Aurora A kinase inhibitors

Keywords: عوامل ضد سرطان; Triphenyl-1H-pyrazole-4-carboxamide; 2D-QSAR; Aurora A kinase; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

New potential phytotherapeutics obtained from white mulberry (Morus alba L.) leaves

Keywords: عوامل ضد سرطان; Morus alba L.; White mulberry leaves; Anticancer agents; Nutraceuticals; Diabetes mellitus;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

In vitro cytotoxicity and antimicrobial activity of Talaromyces flavus SP5 inhabited in the marine sediment of Southern Coast of India

Keywords: عوامل ضد سرطان; Marine sediment fungi; Bioactive compounds; Anti-microbial; Anticancer agents;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase

Keywords: عوامل ضد سرطان; Anticancer agents; Histone deacetylase inhibitors; 2-(Phenylsulfonyl)quinoline

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Differential metabolism of 3FDT and docetaxel in RLMs, rats, and HLMs

Keywords: عوامل ضد سرطان; 3FDT; Anticancer agents; Cytochrome P450; Metabolites3FDT, 3′-N-de-tert-butoxycarbonyl-3′-[2-(1,1,1-trifluoro-2-methyl)propyloxycarbonyl]-docetaxel; CL, intrinsic clearance; Vd, volume of distribution; AUC, area under the plasma concentration; RLMs, rat l

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis of novel nicotinohydrazide and (1,3,4-oxadiazol-2-yl)-6-(trifluoromethyl)pyridine derivatives as potential anticancer agents

Keywords: عوامل ضد سرطان; 1,3,4-Oxadiazole; Nicotinohydrazide; Cyclization; Anticancer agents; Human cancer cell lines;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors

Keywords: عوامل ضد سرطان; 6-aryl quinazolines; Isoform-selective; PI3K-alpha; Breast cancer; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Development of aqueous dispersions of Coenzyme Q10 for pulmonary delivery and the dynamics of active vibrating-mesh aerosolization

Keywords: عوامل ضد سرطان; Lung cancer; Nano-dispersion; Aerosol; Anticancer agents;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

β-Ionone and its analogs as promising anticancer agents

Keywords: عوامل ضد سرطان; β-Ionone; Terpenoid derivatives; Anticancer agents; Anti-proliferative activity; Apoptosis; Drug design;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of indeno[1,2-b]quinoxaline derivatives as potential anticancer agents

Keywords: عوامل ضد سرطان; Indeno[1,2-b]quinoxaline derivatives; Zebrafish xenograft assay; Anticancer agents; Cell cycle; Apoptosis; Antiproliferative activity

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument

Keywords: عوامل ضد سرطان; p53-MDM2 inhibitors; Protein-protein interaction inhibitors; Anticancer agents; Structure-based design;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action

Keywords: عوامل ضد سرطان; Anticancer agents; Ethacrynic acid; Ethacrynic acid derivatives; Glutathione S-Transferase π

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

The molecular shape and the field similarities as criteria to interpret SAR studies for fragment-based design of platinum(IV) anticancer agents. Correlation of physicochemical properties with cytotoxicity

Keywords: عوامل ضد سرطان; Platinum-based drugs; Anticancer agents; Cytotoxicity; Structure-activity relationship; Shape and field similarity; XED field; Drug likeness; Structure-related molecular properties; Stereo-electronic effects;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Anticancer activity of Ru- and Os(arene) compounds of a maleimide-functionalized bioactive pyridinecarbothioamide ligand

Keywords: عوامل ضد سرطان; Ru(arene) complexes; Anticancer agents; Bioorganometallics; Albumin carrier; Maleimide;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, characterization and biological evaluation of novel Ru(II)-arene complexes containing intercalating ligands

Keywords: عوامل ضد سرطان; Anticancer agents; Bioorganometallic chemistry; DNA intercalating ligand; Medicinal inorganic chemistry; Ruthenium(II)-arene complex;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Combretastatin A-4 analogues with benzoxazolone scaffold: Synthesis, structure and biological activity

Keywords: عوامل ضد سرطان; Combretastatin A-4; Stilbene; Benzoxazolone; Anticancer agents; Tubulin binding agents; X-ray;

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors

Keywords: عوامل ضد سرطان; C1-alkyl and arylalkyl substituted xanthones; Anticancer agents; Topoisomerase IIα catalytic inhibitor;

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity

Keywords: عوامل ضد سرطان; C5-curcuminoids synthesis; Anticancer agents; NFκB; Apoptosis; DNA topoisomerase I;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of spiro[cyclopropane-1,3′-indolin]-2′-ones as potential anticancer agents

Keywords: عوامل ضد سرطان; Spirooxindoles; Cyclopropane; Anticancer agents; Structure-activity relationship (SAR);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Exaggerated hypertensive response to combretastatin A-4 phosphate in hypertensive rats: Effective pharmacological inhibition by diltiazem

Keywords: عوامل ضد سرطان; ACEI; angiotensin converting enzyme inhibitor; CA4P; Combretastatin A-4 phosphate; DSS; Dahl salt sensitive; HS; high salt; MAP; mean arterial blood pressure; ND; normal low salt diet; Anticancer agents; Blood pressure; Calcium channel blockers; Cardiac t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents

Keywords: عوامل ضد سرطان; Natural products; Ursolic acid derivatives; Anticancer agents; Drug discovery; Chemical biologyUA, ursolic acid; NF-κB, nuclear factor-κB; STAT3, signal transducer and activator of transcription 3; TRAIL, tumor necrosis factor (TNF)-related apoptosis indu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of podophyllotoxin esters as potential anticancer agents: Synthesis, biological studies and tubulin inhibition properties

Keywords: عوامل ضد سرطان; Podophyllotoxin; CA-4; Tubulin polymerization inhibition; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Prevention of Bone Metastases in Patients with High-risk Nonmetastatic Prostate Cancer Treated with Zoledronic Acid: Efficacy and Safety Results of the Zometa European Study (ZEUS)

Keywords: عوامل ضد سرطان; Androgen deprivation therapy; Anticancer agents; Bisphosphonates; Bone metastases; Prostate cancer; Skeletal-related events; Zoledronic acid;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Modified 2,4-diaryl-5H-indeno[1,2-b]pyridines with hydroxyl and chlorine moiety: Synthesis, anticancer activity, and structure–activity relationship study

Keywords: عوامل ضد سرطان; 2,4-Diaryl-5H-indeno[1,2-b]pyridines; Hydroxyl group; Chlorine group substitution; Anticancer agents; Cytotoxicity; Topoisomerase I and II inhibition

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Caffeine–hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells

Keywords: عوامل ضد سرطان; Anticancer agents; Caffeine–hydrazones; Cancer treatment; Leukaemia; Selectivity

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Development of certain novel N-(2-(2-(2-oxoindolin-3-ylidene)hydrazinecarbonyl)phenyl)-benzamides and 3-(2-oxoindolin-3-ylideneamino)-2-substituted quinazolin-4(3H)-ones as CFM-1 analogs: Design, synthesis, QSAR analysis and anticancer activity

Keywords: عوامل ضد سرطان; Hydrazones; Quinazoline; 2-oxoindolin-3-ylidene; CFM analogues; Anticancer agents

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor

Keywords: عوامل ضد سرطان; Hydroxylated 2,4-diphenyl indenopyridine; Anticancer agents; Terpyridine; Topoisomerase IIα non-intercalative catalytic inhibitor; Antiproliferative activity

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers

Keywords: عوامل ضد سرطان; 3-Phenylquinolinylchalcone derivatives; Anticancer agents; Cell cycle; Apoptosis; Breast cancers;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines

Keywords: عوامل ضد سرطان; Dihydroxylated 2,6-diphenyl-4-aryl pyridines; Topoisomerase I; Topoisomerase II; Cytotoxicity; Anticancer agents;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

4-Nerolidylcatechol analogues as promising anticancer agents

Keywords: عوامل ضد سرطان; 4-Nerolidylcatechol analogues; Anticancer agents; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger's base skeleton

Keywords: عوامل ضد سرطان; NCSQHOMJBRPEHY-UHFFFAOYSA-N; UAZRJCPTZAKVQF-UHFFFAOYSA-N; IGYBTVQKYKVPCU-SZTDCLKKSA-N; JQBUNFAMDZCGAG-GAAYKLLRSA-N; JUXRUBHPFIIZSJ-QJCMXNLUSA-N; UMYNZOGAFGTDDD-GAAYKLLRSA-N; VYKDILFYBGBUGZ-HRPTZAEHSA-N; CQQQFAVMJCZVQO-HRPTZAEHSA-N; YSGIKLYQGQLPQU-BKCXJZAT

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه