Structure, function and targeting of human telomere RNA
Keywords: عوامل ضد سرطان; Human telomere; Telomere RNA; G-quadruplex; Anticancer agents;
مقالات ISI عوامل ضد سرطان (ترجمه نشده)
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Amphiphilic meso(sulfonate ester fluoroaryl)porphyrins: refining the substituents of porphyrin derivatives for phototherapy and diagnostics
Keywords: عوامل ضد سرطان; Porphyrins; Anticancer agents; Imaging agents; Singlet oxygen; Photodynamic therapy; Photosensitizers;
Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues
Keywords: عوامل ضد سرطان; Estradiol–carboplatin analogs; Estradiol–oxaliplatin analogs; Vectorization therapy; Anticancer agents; Estrogen receptor; Breast cancerER+, estrogen-receptor positive; ER−, estrogen-receptor negative; E-CDDP, estradiol-linked platinum(II) complex analog
Structure-based de novo design of Eya2 phosphatase inhibitors
Keywords: عوامل ضد سرطان; De novo design; Eya2 phosphatase; Inhibitor; Chelating group; Anticancer agents
Synthesis and biological activity of novel bifunctional isoxazolidinyl polycyclic aromatic hydrocarbons
Keywords: عوامل ضد سرطان; DNA; Cation recognition; Cycloaddition; Docking; Anticancer agents
Palladium(II), platinum(II) and gold(I) complexes containing chiral diphosphines of the Josiphos and Walphos families – Synthesis and evaluation as anticancer agents
Keywords: عوامل ضد سرطان; Chiral ligands; Diphosphine ligands; Palladium complexes; Platinum complexes; Anticancer agents
Synthesis of 6-substituted 9-methoxy-11H-indeno[1,2-c]quinoline-11-one derivatives as potential anticancer agents
Keywords: عوامل ضد سرطان; Anticancer agents; Indeno[1,2-c]quinolinone derivatives; Cell cycle arrest; Apoptosis
Synthesis and cellular impact of diene–ruthenium(II) complexes: A new class of organoruthenium anticancer agents
Keywords: عوامل ضد سرطان; Ruthenium; Bioorganometallic Chemistry; DNA binding; Anticancer agents; Apoptosis; Cell metabolism
Anti-breast cancer activity of heteroaryl chalcone derivatives
Keywords: عوامل ضد سرطان; Antiproliferative activity; Anticancer agents; Breast cancer; ChalconeCQ, chloroquine; δ ppm, part per million; DMSO, dimethyl sulfoxide; GI50, 50% growth inhibition; IR, infrared; mp, melting point; NMR, nuclear magnetic resonance; ES-MS, electro spray m
Halogenated flavanones as potential apoptosis-inducing agents: Synthesis and biological activity evaluation
Keywords: عوامل ضد سرطان; Anticancer agents; Cytotoxic activity; Apoptosis; Flavanones
Target fishing and docking studies of the novel derivatives of aryl-aminopyridines with potential anticancer activity
Keywords: عوامل ضد سرطان; KITCGZVBVFIXIC-UHFFFAOYSA-NStructure-based drug design; Target fishing; Molecular docking; Aryl-aminopyridines; Anticancer agents
Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors
Keywords: عوامل ضد سرطان; Terphenyls; Suzuki coupling; Benzimidazoles; Anticancer agents; Tubulin polymerization
Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure–activity relationships of neocryptolepines and 6-methyl congeners
Keywords: عوامل ضد سرطان; 5H-Indolo[2,3-b]quinolines; 6H-Indolo[2,3-b]quinolines; Anticancer agents; Antiproliferative acivity
A laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity
Keywords: عوامل ضد سرطان; Biocatalysis; Laccase; Oxidative enzymes; 1,4-Naphthohydroquinones; Aminonaphthoquinones; C–N bond formation; Primary amines; Monoamination; Anticancer agents; Cytostatic effects; Cytotoxic effects; GI50; TGI; LC50
Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study
Keywords: عوامل ضد سرطان; Dihydroxylated 2,4,6-triphenyl pyridines; Topoisomerase I; Topoisomerase II; Cytotoxicity; Anticancer agents
Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells
Keywords: عوامل ضد سرطان; Ras inhibitors; Ras-dependent transformation; Anticancer agents; Drug design; Peptide engineering; Cell-penetrating peptides; Drug delivery
Phenotyping drug disposition in oncology
Keywords: عوامل ضد سرطان; Phenotyping; Anticancer agents; Probe; Pharmacokinetics; Drug disposition; Metabolism; Phase I reactions; Phase II reactions; Drug transporters
Anticancer molecules targeting fibroblast growth factor receptors
Keywords: عوامل ضد سرطان; fibroblast growth factor receptor; receptor tyrosine kinase inhibitors; structure–activity relationship; cancer chemical therapy; anticancer agents
Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones
Keywords: عوامل ضد سرطان; Tyrosine kinase inhibitor; Anticancer agents; Bisindolylmethanone; Quinazoline; Epidermal growth factor receptor (EGFR);
Cytotoxic potential of novel 6,7-dimethoxyquinazolines
Keywords: عوامل ضد سرطان; Quinazolines; Quinazolinones; Colon cancer; Anticancer agents; Ovarian cancer
2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazoles: Search for anticancer agents
Keywords: عوامل ضد سرطان; Synthesis imidazo[2,1-b][1,3,4]thiadiazole; Anticancer agents; NCI
Rhodium(III) and iridium(III) complexes as anticancer agents
Keywords: عوامل ضد سرطان; Rhodium; Iridium; Apoptosis; Anticancer agents; DNA binding; Cell metabolism;
Synthesis and in-vitro anticancer activity of 3,5-bis(indolyl)-1,2,4-thiadiazoles
Keywords: عوامل ضد سرطان; Bisindoles; 1,2,4-Thiadiazoles; Anticancer agents; Dimerization; Hypervalent iodine regents
Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives
Keywords: عوامل ضد سرطان; Chalcone; Retrochalcone; Topoisomerase II; Anticancer agents; Oxiranylmethoxy-chalcone; Thiiranylmethoxy-chalcone;
One-pot synthesis and anticancer studies of 2-arylamino-5-aryl-1,3,4-thiadiazoles
Keywords: عوامل ضد سرطان; 1,3,4-Thidiazoles; Anticancer agents; One-pot synthesis; Cancer cell lines; Oxidative cyclization
Cytotoxic and antivascular 1-methyl-4-(3-fluoro-4-methoxyphenyl)-5-(halophenyl)-imidazoles
Keywords: عوامل ضد سرطان; Combretastatin A-4; HUVEC; Angiogenesis; Anticancer agents; Cytotoxicity
Identification of novel BRAF kinase inhibitors with structure-based virtual screening
Keywords: عوامل ضد سرطان; Virtual screening; Docking; BRAF inhibitor; Anticancer agents
Structure-based virtual screening approach to the discovery of phosphoinositide 3-kinase alpha inhibitors
Keywords: عوامل ضد سرطان; Virtual screening; Docking; PI3Kα; Inhibitor; Anticancer agents
Novel C8-linked pyrrolobenzodiazepine (PBD)–heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box
Keywords: عوامل ضد سرطان; Pyrrolobenzodiazepine (PBD)-conjugate; Inverted CCAAT box; Nuclear Factor Y; Topoisomerase IIα; Anticancer agents
Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative
Keywords: عوامل ضد سرطان; Coumarins; Preferential cytotoxicity; Pancreatic cancer; PANC-1; Anticancer agents
Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors
Keywords: عوامل ضد سرطان; HDAC; Histone deacetylase; HDAC-inhibitors; Molecular modeling; Hydroxamic acids; Cell-cycle arrest; Anticancer agents;
Adamantane–platinum conjugate hosted in β-cyclodextrin: Enhancing transport and cytotoxicity by noncovalent modification
Keywords: عوامل ضد سرطان; Anticancer agents; DNA; Cyclodextrins; Host–guest chemistry; Solvation; Noncovalent modification
Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors
Keywords: عوامل ضد سرطان; 4-β-Amino-4â²-O-demethyl-4-desoxypodophyllotoxin; Aroylthiourea; Anticancer agents; Topoisomerase II;
Metabolic and electrochemical mechanisms of dimeric naphthoquinones cytotoxicity in breast cancer cells
Keywords: عوامل ضد سرطان; Dimeric naphthoquinones; Anticancer agents; Cytotoxicity; Oxidative stress; Tumor metabolism;
Impact of aryloxy-linked quinazolines: A novel series of selective VEGFR-2 receptor tyrosine kinase inhibitors
Keywords: عوامل ضد سرطان; Quinazoline; EGFR; VEGFR2; RTK inhibitors; Anticancer agents
Structure based design of heat shock protein 90 inhibitors acting as anticancer agents
Keywords: عوامل ضد سرطان; HSP90; SBDD; Virtual screening; Anticancer agents;
Synthesis and biological activity of ferrocenyl derivatives of the non-steroidal antiandrogens flutamide and bicalutamide
Keywords: عوامل ضد سرطان; Anticancer agents; Antiandrogen; Ferrocene; Prostate cancer; Flutamide; Bicalutamide
Polyfluorinated bipyridine cisplatins manipulate cytotoxicity through the induction of S-G2/M arrest and partial intercalation mechanism
Keywords: عوامل ضد سرطان; Antiproliferative effect; Anticancer agents; Cell cycle progression; DNA intercalation mechanism; Polyfluorinated bipyridine cisplatin complexes;
Polymer conjugates of the highly potent cytostatic drug 2-pyrrolinodoxorubicin
Keywords: عوامل ضد سرطان; Polymer conjugates; Tumor drug delivery; pH-controlled release; Anticancer agents; Multidrug resistance
Synthesis of novel 1,2,4-oxadiazoles and analogues as potential anticancer agents
Keywords: عوامل ضد سرطان; 1,2,4-Oxadiazole; 1,3,4-Thiadiazole; Anticancer agents
Development of classification model batteries for predicting inhibition of tubulin polymerization by small molecules
Keywords: عوامل ضد سرطان; Anticancer agents; Decision tree; Classification model; Tubulin polymerization;
Azide derivatized anticancer agents of Vitamin K3: X-ray structural, DSC, resonance spectral and API studies
Keywords: عوامل ضد سرطان; Electronic isomers; RAHB (resonance assisted H-bonding); API (Active Pharmaceutical Ingredients); Vitamin K3; Anticancer agents
Highly cytotoxic substitutionally inert rhodium(III) tris(chelate) complexes: DNA binding modes and biological impact on human cancer cells
Keywords: عوامل ضد سرطان; Rhodium; Polypyridyl ligands; DNA binding; Anticancer agents; Cell metabolism; Apoptosis
Consensus-Based Evaluation of Clinical Significance and Management of Anticancer Drug Interactions
Keywords: عوامل ضد سرطان; anticancer agents; clinical effect; consensus; drug interactions
Can phytochemical antioxidant rich foods act as anti-cancer agents?
Keywords: عوامل ضد سرطان; Oxidative stress; ROS; Antioxidants; Anticancer agents
Biomarkers of occupational exposure do anticancer agents: A minireview
Keywords: عوامل ضد سرطان; Anticancer agents; Occupational exposure; Biomarkers
Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents
Keywords: عوامل ضد سرطان; Anticancer agents; Water soluble nitrogen mustards; DNA interstrand cross-linking agents; Cell cycle;
Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents
Keywords: عوامل ضد سرطان; Pyrrolobenzodiazepine; Estradiol; Anticancer agents; Tubulin polymerisation; Apoptosis; Tunel assay; p53; p21; HDACs
Synthesis and biological evaluation of indolyl chalcones as antitumor agents
Keywords: عوامل ضد سرطان; Indolyl chalcones; Anticancer agents; 1,3-Diaryl-2-propen-1-ones
Reaction of reductively activated mitomycin C with aqueous bicarbonate: Isolation and characterization of an oxazolidinone derivative of cis-1-hydroxy-2,7-diaminomitosene
Keywords: عوامل ضد سرطان; Anticancer agents; Mitomycin C; Bicarbonate; Alkylation; Metabolites; Oxazolidinones