Keywords: Arsenic; Autophagy inhibitor; ER stress; Proteostasis; Oxidative stress; ATF6; activating transcription factor 6; DCF; 2â²,7â²-dichlorofluorescein; H2DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; EIF2S1/eIF2α; eukaryotic initiation factor 2, s
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Keywords: AO/EB; acridine orange/ethidium bromide; ATF6; activating transcription factor 6; BBB; blood-brain barrier; BSA; bovine serum; Ca2+; calcium; DAPI; 4,6-diamino-2-pheno-lindol dihydrochloride; DCF; 2',7'-dichloroï¬uorescein; DCFH-DA; 2',7'-dichlor
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
Keywords: ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related; AMPK; AMP-activated protein kinase; AD; Alzheimer's disease; ARE; antioxidant response element; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BRAC1; Breast cancer 1
Keywords: UPR; PERK; ATF6; IRE1; XBP1s; Ischemic heart disease; ER stress;
Keywords: ASC; apoptosis-associated speck-like protein containing a CARD; ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; DAMPs; damage-associated molecular patterns; gAcrp; globular adiponectin; HBSS; Hank's balanced salt solution; HO-1;
Keywords: PGMO; Pre-gestational maternal obesity; PGMN; Pre-gestational maternal normal weight; HUVECs; Human umbilical vein endothelial cells; NO; Nitric oxide; NOS; Nitric oxide synthase; eNOS; endothelial nitric oxide synthase; Akt; Protein kinase B/Akt; ER; end
Keywords: AD; Alzheimer's disease; ATF6; activating transcription factor 6; CHOP; transcriptional factor C/EBP homologous protein; DNP; dinitrophenol; ER; endoplasmic reticulum; eIF2α; eukaryotic initiation factor 2α; HD; Huntington's disease; HNE; 4-hydroxynonen
Kimchi methanol extracts attenuate hepatic steatosis induced by high cholesterol diet in low-density lipoprotein receptor knockout mice through inhibition of endoplasmic reticulum stress
Keywords: ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; Bax; Bcl-2-associated X protein; CAT; catalase; CHOP; CCAAT-enhancer-binding protein homologous protein; cIAP; inhibitor of apoptosis protein; DAB; diaminobenzidine; ECL; enhanced chemilum
Keywords: AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; CHOP; C/EBP homologous protein; DRP1; dynamin-related protein 1; FIS1; fission protein 1; GRP78; 78Â kDa glucose-regulat
Keywords: ATF6; activating transcription factor 6; CHOP; CCAAT-enhancer-binding protein homologous protein; eIF2α; eukaryotic translation initiation factor 2α; ERAD; Endoplasmic-reticulum-associated protein degradation; GRP78; Glucose-related protein78; IR; insul
Keywords: 4-PBA; 4-phenylbutyric acid; ARA; arachidonic acid; ATF6; activating transcription factor 6; BiP or Grp78; 78-kDa glucose regulated protein; COX; cyclooxygenase; CYP; cytochrome P450; DHA; docosahexaenoic acid; eIF2α; eukaryotic translation initiation fa
Keywords: ATF6; activating transcription factor 6; CHOP; C/EBP-homologous protein; CVD; cardiovascular disease; eIF2α; eukaryotic translation initiator factor 2α; ER; endoplasmic reticulum; GRP78; glucose regulated protein 78; IDL; intermediate-density lipoprotei
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer
Keywords: 27-OHC; 27-hydroxycholesterol; ADT; androgen deprivation therapy; AR; androgen receptor; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; C/EBP; CCAAT / Enhancer binding proteins; CHOP; C/EBP homologous protein; CIP2A; can
Keywords: CNS; central nervous system; ER; endoplasmic reticulum; Hcy; homocysteine; tHcy; total fasting homocysteine; HHcy; hyperhomocysteinemia; CBS; cystathionine β-synthase; BHMT; betaine methyltransferase; UPR; unfolded protein response; MTHFR; methylene tetr
Keywords: ACP2; lysosomal acid phosphatase; ACP5; tartrate-resistant lysosomal acid phosphatase; ATF6; activating transcription factor 6; Canx; calnexin; CHO-7; Chinese hamster ovary cells; DAPI; 4â²,6â²-diamidino-2-phenylindol; DMAP; DNA methyltransferase-associ
Keywords: PAH; pulmonary artery hypertension; PBS; phosphate buffer; qRT-PCR; quantitative real time; ARDS; acute respiratory distress syndrome; ARE; anti-oxidant responsive element; Atg4; autophagy related 4; ATF6; activating transcription factor 6; Chop; C/EBP [C
Keywords: AA; Angelica Archangelica; AGNHW; AnGongNiuHuang Wan; AM; Astragalus membranaceus; AMP; adenosine monophosphate; AMPK; adenosine 5â²-monophosphate activated protein kinase; Ang II; angiotensin II; AP; Astragalus polysaccharide; ASIV; astragaloside IV; AS
Keywords: Photoreceptor; Retinitis pigmentosa; Achromatopsia; Rhodopsin; ATF6; Retina;
Keywords: ER stress; KSHV; IRE1α; PERK; Primary effusion lymphoma; Unfolded protein response; ATF6; activating transcription factor-6; CHOP; CCAAT/enhancer-binding protein-homologous protein; ER; endoplasmic reticulum; GADD34; growth arrest and DNA damage gene-34;
Keywords: Unfolded protein response; Myeloid cells; T cells; Inflammation; Cell-nonautonomous; Tumor microenvironment; APC; antigen presenting cells; ATF6; activating transcription factor 6; CHOP; CCAAT/-enhancer binding protein homologous protein; DC; dendritic ce
Keywords: Unfolded protein response; endoplasmic reticulum stress; asthma; house dust mite; protein disulfide isomerase; endoplasmic reticulum protein 57; recombination-activating gene 1; epithelium; airways hyperresponsiveness; AEC; Airways epithelial cell; AHR; A
Keywords: BTX; bungarotoxin; CME; clathrin-mediated endocytosis; ER stress; endoplasmic reticulum stress; ERAD; endoplasmic reticulum-associated degradation; MβCD; methyl-beta-cyclodextrin; MFI; mean fluorescence intensity; AChR; acetylcholine receptor; ATF6; acti
Keywords: ER; endoplasmic reticulum; THG; thapsigargin; PDI; protein disulfide isomerase; TMX; thioredoxin-related-transmembrane proteins; UPR; unfolded protein response; PERK; pancreatic ER kinase PKR-like ER kinase; ATF6; activating transcription factor-6; IRE1;
Keywords: ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; CHOP; CCAAT/enhancer binding protein-homologous protein; cyt c; cytochrome c; eIF2α; eukaryotic translation initiation factor-2α; ER stress; endoplasmic reticulum stress;
Keywords: ARHL; age-related hearing loss; ATF6; activating transcription factor 6; ER; endoplasmic reticulum; Bcl-2; B-cell lymphoma 2 protein; CHOP; C/EBP homologous protein; ERAD; ER-associated protein degradation; GRP78; glucose-regulated protein 78Â kD; OHC; ou
Keywords: Omega-6:omega-3; Nonalcoholic fatty-liver disease; High-fat diet; α-Linolenic acid; Colitis; Murine model; 4-HNE; 4-hydroxy-2-nonenal; AA; arachidonic acid; ALA; alpha-linolenic acid; ATF6; activating transcription factor 6; BiP; binding immunoglobulin p
Keywords: ASK1; apoptosis signal-regulating kinase; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; ATF6; activating transcription factor 6; Atg12; autophagy-related gene 12; C9ORF72; chromosome 9 open reading frame 72; CHIP; carbo
Keywords: ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; CNS; central nervous system; ER; endoplasmic reticulum; ERS; endoplasmic reticulum stress; GRP78; 78-kDa glucose-regulated protein; IRE1; inositol-requiring enzyme 1; JNK; c-JUN NH2-
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; AD; Alzheimer's disease; APP; amyloid precursor protein; GRP78/BiP; chaperone glucose-regulated protein 78; PERK; protein kinase RNA (PKR)-like ER kinase; ATF6; activating transcription factor 6;
Keywords: ALDH2; aldehyde dehydrogenase 2; ANT; adenine nucleotide transportor; AR; aldose reductase; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATG; AuTophaGy; ATM; ataxia-telangiectasia mutate; COPD; chronic obstructive pulmonary
Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
Keywords: ATF6; activating transcription factor 6; BiP; heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa); GSMA; gel shift mobility assay; HO-1; heme oxygenase 1; IL-1β; interleukin 1 beta; IRE1α; inositol-requiring protein 1; NF-κB; nuclear fact
Keywords: ATF4; activating transcription factor 4 (also designated as CREB-2, cAMP response element (CRE) binding protein2); ATF6; activating transcription factor 6; BSA; bovine serum albumin; CHOP; CCAAT/enhancer-binding protein-homologous protein; CNS; central ne
Keywords: AGER; advanced glycosylation end product-specific receptor; ALOX5; arachidonate 5-lipoxygenase; ANT; adenine nucleotide translocase; ASK1; apoptosis signal-regulating kinase 1; aSMase; acidic sphingomyelinase; ATF6; activating transcription factor 6; CFLA
Hepatic conditional knockout of ATF6 exacerbates liver metabolic damage by repressing autophage through MTOR pathway
Keywords: Metabolism; ATF6; Conditional knockout; Autophage; ATF6; activating transcription factor 6; UPR; unfolded protein response; GTT; glucose tolerance test; ITT; insulin tolerance test; RES; resveratrol; DEX; dexamethasone; FSK; forskolin; TG; triglyceride; T
TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice
Keywords: ATF6α; ER stress; Insulin resistance; TSPA; T2DM; Akt; protein kinase B; ATF6; activating transcription factor 6; CHOP; C/EBP-homologous protein; CNX; calnexin; CRT; calreticulin; CREB; cAMP response element binding protein; ER; Endoplasmic reticulum; ER
Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death
Keywords: S1P inhibition; SREBP; ATF6; PF-429242; ER stress; UPR inhibition;
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes
Keywords: TRPV6 channel; Human embryonic stem cells; ER stress; ATF6; JNK signaling pathway;
CREB element is essential for unfolded protein response (UPR) mediating the Cu-induced changes of hepatic lipogenic metabolism in Chinese yellow catfish (Pelteobagrus fulvidraco)
Keywords: ACC; Acetyl-CoA carboxylase; CREB; cAMP-response element binding protein; ATF6; Activating transcription factor 6; ER; endoplasmic reticulum; ERSE; ER stress response element; FAS; Fatty acid synthase; GRP78/BiP; 78-kDa glucose-regulated protein; IRE1; In
Long-term exposure to high-sucrose diet down-regulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned male mice
Keywords: GAPDH; glyceraldehyde-3-phosphate dehydrogenase; ChREBP; carbohydrate-responsive element-binding protein; SREBP-1c; sterol regulatory element-binding protein 1c; SCD1; stearoyl-CoA desaturase-1; FASN; fatty acid synthase; CPT-1α; carnitine palmitoyltrans
Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation
Keywords: Glucagon-like peptide-1; Exendin-4; Nuclear factor erythroid-derived 2-related factor 2; Endoplasmic reticulum stress; Nonalcoholic fatty liver disease; ATF6; Activation transcription factor-6; Bip; Binding immunoglobulin protein; CHOP; C/EBP homologous p
Loss of C/EBP-β LIP drives cisplatin resistance in malignant pleural mesothelioma
Keywords: ANOVA; analysis of variance; ATF6; activating transcription factor 6; C/EBP; CAAT/enhancer binding protein; IRE1; inositol-requiring enzyme 1; CHOP/GADD153; C/EBP homologous protein/growth arrest/DNA damage inducible 153; CEA; carcino-embrionic antigen; C
Aberrant endoplasmic reticulum stress mediates coronary artery spasm through regulating MLCK/MLC2 pathway
Keywords: ER; endoplasmic reticulum; CAS; coronary artery spasm; MLCK; myosin light chain kinase; MLC2; myosin II regulatory light chain; VSMCs; vascular smooth muscle cells; 4-PBA; 4-phenylacetic acid; Tm; tunicamycin; UPR; unfolded protein reaction; IRE1; inosito
Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction
Keywords: Shear stress; Nitric oxide; Protein kinase RNA-like endoplasmic reticulum kinase; Mesenteric resistance artery; Ach; Acetylcholine; ATF6; Activated Transcription Factor 6; BAX; Bcl-2-Associated X Protein; BCL2; B-Cell Lymphoma 2; CHOP; C/EBP Homologous
Identification and functional characterization of unfolded protein response transcription factor ATF6 gene in kuruma shrimp Marsupenaeus japonicus
Keywords: UPR; ATF6; WSSV; Marsupenaeus japonicus; Innate immunity;
Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes
Keywords: Ac-DEVD-AMC; N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin; AKT; protein kinase B; AMP; ampicillin; ATB; antibiotic; ATF6; activating transcription factor 6; BC; bile canaliculi; BSEP; bile salt export pump; CDF; 5(6)-carboxy-2,7-dichlorofluorescein;
Developmental and extrahepatic physiological functions of SREBP pathway genes in mice
Keywords: AAV; adeno-associated virus; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; ADD1; adipocyte determination- and differentiation-dependent factor 1; APP; amyloid precursor protein; Api6; apoptosis inhibitor 6; ApoE; apolipoprotein E; ATF6; activati
Paraptosis in human glioblastoma cell line induced by curcumin
Keywords: Cell Death; Paraptosis; Curcumin; Endoplasmic Reticulum Stress Response; miRNAs; AKT; Serine-threonine kinase; ATF6; Activating transcription factor 6; BCL2; B- Cell lymphoma 2; BIP; Immunoglobulin-heavy-chain binding protein; CHOP; C/EBPhomologous protei
ER stress and cancer: The FOXO forkhead transcription factor link
Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating