دانلود مقالات ISI درباره Brct + ترجمه فارسی

بررسی کوتاه در مورد پیامدهای مسیر اصلاح پایه برای نورون: مربوط به بیماری های نوروژنیک

A short review on the implications of base excision repair pathway for neurons: Relevance to neurodegenerative diseases

Keywords: AD; Alzheimer's disease; AP site; apurinic/apyrimidinic site; APE1; apurinic/apyrimidinic endonuclease 1; Aβ; amyloid beta; BER; base excision repair; CaMKII; Ca2 +/Calmodulin-Dependent Protein Kinase II; CDK; cyclin-dependent kinase; CREB; cAMP respons

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

پیوستن به انتهای غیرخطی: راه حل خوبی برای پایان دادن به بد است

Nonhomologous end joining: A good solution for bad ends

Keywords: Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

سندرم شکستن نیهمگن: راه های ترخیص برای پروتئین نایروانی جهش یافته خاص آلل است

Nijmegen breakage syndrome: The clearance pathway for mutant nibrin protein is allele specific

Keywords: BRCT; BRCA1 C-Terminus; DSB; DNA double-strand break; LCL; lymphoblastoid cell line; NBN; nibrin; NBS; Nijmegen breakage syndrome; PMN; piecemeal microautophagy of the nucleus; RT-PCR; reverse transcription polymerase chain reaction; DNA repair; Proteasom

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway

Keywords: ARE; antioxidative response element; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; BRCA1; breast cancer susceptibility protein 1; BRCT; BRCA1 C-terminal; BER; base excision repair; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Difference in Risk of Breast and Ovarian Cancer According to Putative Functional Domain Regions in Korean BRCA1/2 Mutation Carriers

Keywords: BRCA; BRC repeats; BRCT; Parity; Risk factor;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Single-molecule sorting of DNA helicases

Keywords: ATP; adenosine triphosphate; BAP; biotin acceptor peptide; bio; biotinylated; BLM; Bloom's syndrome DNA helicase; BRC1; Breast cancer type 1 protein; BRCT; BRCA1 C-terminus; DMEM; Dulbecco's modified eagle medium; DNA; deoxyribonucleic acid; ds; doubl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif

Keywords: BRCT; Tandem BRCT domains; BRCA1; Phosphopeptide; DNA damage response; pSXXF motif; DDR; DNA damage response; PIKKs; phosphoinositide 3-kinase-related kinases; BRCA1; breast cancer susceptibility gene 1; HBOC; hereditary breast and ovarian cancer; BRCT; B

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Biophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domain

Keywords: FA; Fanconi anemia; ICL; interstrand cross-link; DSB; double-strand break; HR; homologous recombination; MMC; mitomycin C; DEB; diepoxybutane; TLS; translesion synthesis; NER; nucleotide excision repair; FAAP20; Fanconi anemia-associated protein 20; UBZ4;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains

Keywords: APLF; aprataxin- and PNK-like factor; PNKP; polynucleotide kinase phosphatase; FHA; forkhead-associated; XRCC1; X-ray repair cross-complementing protein 1; XRCC4; X-ray repair cross-complementing protein 4; PARP-1; poly(ADP-ribose)polymerase 1; NHEJ; non-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair

Keywords: Mre11-Rad50-Nbs1; CtIP; Allostery; Double strand break repair; Dynamics; Conformational change; AFM; atomic force microscopy; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCT; BRCA1 C-terminus domain; DSB; DNA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

RecQ helicases and PARP1 team up in maintaining genome integrity

Keywords: ARTD; ADP-ribosyltransferase diphtheria toxin-like; BER; base excision repair; BG; Baller-Gerold syndrome; BLM; Bloom syndrome protein; BRCT; BRCA1 C-terminus domain; BS; Bloom syndrome; CPT; camptothecin; dHJ; double Holliday junction; DSB; DNA double-st

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding

Keywords: BRCT; BRCA1 C-terminal domain; ChIP; chromatin immunoprecipitation; DSB; double-strand break; GAL1-cs; GAL1 promoter cut-site; MRX; Mre11-Rad50-Xrs2 complex; NHEJ; nonhomologous end-joining; PCR; polymerase chain reaction; Double-strand break; Nonhomo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy

Keywords: BRCA1; breast cancer susceptibility gene 1; BRCT; Brca1 C-terminal; CHIP; chaperone-associated ubiquitin ligase; CYLD; cylindromatosis; DAPK; death-associated protein kinase; DUB; deubiquitinating enzyme); EGF; epidermal growth factor; FADD; fas-associate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

N-terminal domains of human DNA polymerase lambda promote primer realignment during translesion DNA synthesis

Keywords: 8-oxodG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP; apurinic/apyrimidinic; BER; base excision repair; BSA; bovine serum albumin; BRCT; BRCA1 C-terminal domain; dNTP; 2′-deoxynucleoside 5′-triphosphate; dPolλ; deletion of human DNA polymerase λ (132-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

C-terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin

Keywords: IR; ionizing radiation; DSB; double-strand break; NHEJ; non-homologous end-joining; PNKP; polynucleotide kinase/phosphatase; LIG4; DNA ligase IV; APLF; aprataxin- and PNK-like factor; BRCT; breast cancer associated 1 C-terminal; FBS; fetal bovine serum; L

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting DNA damage response: Threshold, chromatin landscape and beyond

Keywords: DSBs; double strand breaks; γ-H2AX; phosphorylation of histone variant H2AX in Ser139; SUMO; small ubiquitin modifier; ROS; reactive oxygen species; IR; ionizing radiation; Tip60; Tat-interactive 60; HAT; histone acetyltransferase; HDAC; histone deacetyl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

High Fcp1 phosphatase activity contributes to setting an intense transcription rate required in Drosophila nurse and follicular cells for egg production

Keywords: CTD; carboxyl terminal domain; Fcp1; TFIIF-interacting CTD phosphatase; RNAPII; RNA polymerase II; PIC; preinitiation complex; Ser; serine; TFIIF; general transcription factor II F; BRCT; Brca-1 C-terminal; Scp; small CTD phosphatase; Q-RT-PCR; quantitati

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The BRCA1 alternative splicing variant Δ14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells

Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; AURKA; Aurora kinase A; BC; breast cancer; BRCA1/2; breast cancer-associated gene 1/2; BRCT; BRCA1 C-terminal domain; B2M; beta-2-microglobulin; Cdk2; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure

Keywords: BRCT; BRCA1 C-terminal domain; IRIF; Ionizing Radiation-Induced Foci; DSBs; double-stranded DNA breaks sites; DDR; DNA damage response; H2AX; histone 2A variant X; hTERT; human telomerase reverse transcriptase; SWI-SNF; switching defective/sucrose non-f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The application of modular protein domains in proteomics

Keywords: pTyr; phosphotyrosine; PTM; post-translational modification; MS; mass spectrometry; PSSM; position specific scoring matrix; SH2; Src homology 2; SH3; Src homology 3; WW; tryptophan tryptophan; PDZ; post synaptic density protein 95-disks large protein 4-zo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2012 سفارش ترجمه

Structural basis of γH2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathway

Keywords: PTIP; Pax2 transactivation domain interaction protein; BRCT; BRCA1 C-terminal domain; DDR; DNA damage response; IR; ionizing radiation; FPA; fluorescence polarization assays; IRIF; ionizing radiation-induced focus; RMSD; root mean-square deviation; PA1; P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Cell cycle-dependent conjugation of endogenous BRCA1 protein with SUMO-2/3

Keywords: SUMO; small ubiquitin-like modifiers; SIM; SUMO interacting motifs; BRCT; BRCA1 C-terminus; BRCA1; SUMO-2/3; Cell cycle; Protein processing; Post-translational; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Thermal and chemical denaturation of the BRCT functional module of human 53BP1

Keywords: Thermal stability; 53BP1; BRCT; High-accuracy DSC; CD; Fluorescence spectroscopy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner

Keywords: BRCT; BRCA1 C-terminus; DDR; DNA damage response; DSB; DNA double-strand break; DUB; deubiquitinase; FHA; forkhead associated; GST; glutathione S-transferase; a.a.; amino acids; NCS; neocarzinostatin; IP; immunoprecipitate; IR; ionizing radiation; PTM; po

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Cloning and characterization of a new BRCA1 variant: A role for BRCT domains in apoptosis

Keywords: Breast cancer; BRCA1; Alternative splicing; BRCT; Apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Many roads lead to primary autosomal recessive microcephaly

Keywords: 53BP1; tumor-suppressor protein p53 binding protein 1; APC; anaphase-promoting complex; ASPM; abnormal spindle-like, microcephaly associated protein; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and RAD3-related protein; BACH1; BRCA1-ass

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2010 سفارش ترجمه

Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping

Keywords: cdc13-1; Cell cycle checkpoint; H2A phosphorylation; BRCT; Telomere

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT–phosphoprotein interaction

Keywords: Quantitative high-throughput screening; BRCT; pBACH1; Fluorescence polarization assay; Hotspot interaction; 1536-Well plate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Structure of an Xrcc4–DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode

Keywords: DNA repair; Xrcc4; DNA ligase IV; BRCT; Coiled-coil

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

ACCA Phosphopeptide Recognition by the BRCT Repeats of BRCA1

Keywords: BRCT; ACCA; phosphopeptide; protein modelling; protein–protein interactionBRCA1, breast cancer susceptibility gene 1; BRCT, BRCA1 C terminus; ACCA, acetyl CoenzymeA carboxylase alpha; FAS, fatty acid synthase; AMPK, AMP-activated protein kinase; GST, glut

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Poly(ADP-ribose) polymerase-1 mediated caspase-independent cell death after ischemia/reperfusion

Keywords: AcDEVD.cmk; acetyl-Asp-Glu-Val-Asp-chloromethylketone; AIF; Apoptosis-inducing factor; BocD.fmk; bocaspartyl-(OMe)-fluoromethylketone; BRCT; BRCA1 carboxy-terminus; CAD; caspase-activated DNAse; DBD; DNA-binding domain; Endo G; endonuclease G; HOCl; hypoc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Localization of checkpoint and repair proteins in eukaryotes

Keywords: Double-strand break; Replication; DNA damage; Checkpoint; Foci; Homologous recombination; Non-homologous end-joining; Repair center; DSB; double-strand break; NHEJ; non-homologous end-joining; HR; homologous recombination; RP-A; replication protein A; BRC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability

Keywords: XRCC1; X-ray repair cross-complementing gene 1; Pol-β; DNA polymerase-β; PARP-1; poly(ADP-ribose) polymerase 1; Lig III α; DNA ligase III α; APE1; apurinic/apyrimidinic endonuclease 1; CHO; Chinese hamster ovary; BER; base excision repair; SSBR; singl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1

Keywords: BRCT; BRCA1; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه