Keywords: فیبروبلاست وابسته به سرطان; CAF; cancer-associated fibroblast; CRC; colorectal cancer; FAP; fibroblast activation protein; H&E; hematoxylin-and-eosin; HGP; histopathological growth pattern; LSEC; liver sinusoidal endothelial cells; OS; overall survival; VEGF; vascular endothelial gr
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Keywords: فیبروبلاست وابسته به سرطان; ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
Keywords: فیبروبلاست وابسته به سرطان; Adipocyte; Breast cancer; Tumor-stroma interaction; CAF; cancer-associated fibroblast; WAT; white adipose tissue; CLS; crown-like structure; CAA; cancer-associated adipocyte; ECM; extracellular matrix; IL; interleukin; ER; estrogen receptor; TNBC; triple-
Keywords: فیبروبلاست وابسته به سرطان; Peroxisome; Cancer; Pexophagy; Plasmalogen; Mitochondrion; Metabolism; AA; arachidonic acid; ABCD; ATP-binding cassette (ABC) transporters subfamily D; ACOX; Acyl Coenzyme-A oxidase; AGPS; alkyl-glycerone phosphate synthase; AMACR; α-Methylacyl-CoA racem
Keywords: فیبروبلاست وابسته به سرطان; ALK; anaplastic lymphoma kinase; CAF; cancer-associated fibroblast; CSC; cancer stem cell; CRC; colorectal cancer; EMT; epithelial-to-mesenchymal transition; EGFR; epidermal growth factor receptor; HH; hedgehog; HGF; hepatocyte growth factor; IGF; insulin
Keywords: فیبروبلاست وابسته به سرطان; Polymeric micelles; Sonic hedgehog signaling; Pancreatic cancer; Stromal modulation; Cancer-associated fibroblast;
Keywords: فیبروبلاست وابسته به سرطان; AR; androgen receptor; ARPI; androgen receptor pathway inhibition; CRPC; castrate-resistant prostate cancer; PCa; prostate cancer; BPH; benign prostate hyperplasia; ERα; estrogen receptor-α; PR; progesterone receptor; PRA; PR isoform A; PRB; PRB isoform
Keywords: فیبروبلاست وابسته به سرطان; AI; aromatase inhibitor; AR; androgen receptor; CAF; cancer-associated fibroblast; CBR; clinical benefit rate; CDK; cyclin-dependent kinase; ctDNA; circulating tumor DNA; DNMT3B; DNA methyltransferase 3B; ER; estrogen receptor; ESR1; ER gene; HDAC1; histo
Keywords: فیبروبلاست وابسته به سرطان; Intrahepatic cholangiocarcinoma; Cancer-associated fibroblast; α-SMA; FSP-1; PDGFRβ;
Keywords: فیبروبلاست وابسته به سرطان; AKT1/AKT; AKT serine/threonine kinase 1; AXL; AXL receptor tyrosine kinase; Bmi1; BMI1 proto-oncogene, polycomb ring finger; CAF; cancer-associated fibroblast; CDH/CAD; cadherin; CRKL; CRK Like Proto-Oncogene; CSC; cancer stem cell; CSF-1; colony-stimulat
Keywords: فیبروبلاست وابسته به سرطان; TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: فیبروبلاست وابسته به سرطان; ACL; ATP citrate lyase; AMPK; adenosine monophosphate kinase; ARG1; l-arginine-metabolizing enzyme arginase 1; BCAA; branched-chain amino acid; Bcl2; B-cell lymphoma 2; CAF; cancer-associated fibroblast; CIC; cancer-initiating cell; COX2; cytochrome oxida
Keywords: فیبروبلاست وابسته به سرطان; CAF; Colon Cancer; IBD; Mesenchyme; α-SMA; α-smooth muscle actin; AOM; azoxymethane; BMP; bone morphogenetic protein; CAC; colitis-associated cancer; CAF; cancer-associated fibroblast; CCL; C-C motif chemokine ligand; COX-2; cyclooxygenase 2; CRC; co
Keywords: فیبروبلاست وابسته به سرطان; AKT; protein kinase B (a serine/threonine kinase); CAF; cancer-associated fibroblast; CTGF; connective tissue growth factor; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; ER; estrogen receptor;
Keywords: فیبروبلاست وابسته به سرطان; Ab; antibody; ACT; adoptive cell therapy; ANG; angiopoietin; ATP; adenosine triphosphate; BMDC; bone marrow derived cell; CA4P; combretastatin A phosphate; CAF; cancer-associated fibroblast; CCL2; C-C motif ligand 2; CD; cluster differentiation antigen; C
Keywords: فیبروبلاست وابسته به سرطان; TME; tumour microenvironment; MSC; mesenchymal stem cell; NK; natural killer; APC; antigen presenting cell; EC; endothelial cell; ECM; extracellular matrix; CAF; cancer-associated fibroblast; EMT; epithelial-mesenchymal transition; αSMA; alpha smooth m
Keywords: فیبروبلاست وابسته به سرطان; ABC; ATP-binding cassette; ALDH; aldehyde dehydrogenase; CAF; cancer-associated fibroblast; CSC; cancer stem cell; EMT; epithelial-to-mesenchymal transition; FACS; fluorescence-activated cell sorting; LSC; leukemic stem cell; mAb; monoclonal antibody; MGM
Keywords: فیبروبلاست وابسته به سرطان; CAF; cancer-associated fibroblast; COX; cyclooxygenase; CYP; cytochrome P450; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition; GPx; glutathione peroxidase; HIF-1; hypoxia-inducible transcription factor-1; JNK; c-Jun NH2-terminal kinas
Keywords: فیبروبلاست وابسته به سرطان; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; AMP-activated protein kinase; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CA; carbonic anhydrase; CAF; cancer-associated fibroblast; CHC; α-cyano-4-hydr
Keywords: فیبروبلاست وابسته به سرطان; Myofibroblast; Cancer-associated fibroblast; Rectal cancer; Neoadjuvant therapy;
Keywords: فیبروبلاست وابسته به سرطان; Tumor microenvironment; Colorectal cancer; Cancer-associated fibroblast; Proteomics; Secretome; Follistatin-related protein 1
Keywords: فیبروبلاست وابسته به سرطان; Tumor microenvironment; Mesenchymal cells; Cancer-associated fibroblast; Pericyte
Keywords: فیبروبلاست وابسته به سرطان; EGFR; epidermal growth factor receptor; NSCLC; non-small cell lung cancer; TKI; tyrosine kinase inhibitor; WT; wild type; KRAS; Kirsten RNA associated rat sarcoma 2 virus gene; PTEN; phosphatase and tensin homolog; HGF; hepatocyte growth factor; IGF1R; in
Keywords: فیبروبلاست وابسته به سرطان; AKAP12; Animal study; Cancer-associated fibroblast; Colchicine; Hepatocellular carcinoma; TGFB2;
Reprogramming tumor stroma using an endogenous lipid lipoxin A4 to treat pancreatic cancer
Keywords: فیبروبلاست وابسته به سرطان; Lipoxin A4; Pancreatic stellate cells; Cancer-associated fibroblasts; Pancreatic cancer; Tumor stroma; Human pancreatic stellate cell; hPSC; Cancer-associated fibroblast; CAF; Pancreatic ductal adenocarcinoma; PDAC; Lipoxin A4; LXA4; Lipoxin B4; LXB4; Tra
PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma
Keywords: فیبروبلاست وابسته به سرطان; 3T3; NIH3T3 mouse fibroblast cells; CAF; cancer-associated fibroblast; CAFM; CAF-conditioned media; CHX; cyclohexamide; DMSO; dimethyl sulfoxide; EpM; epithelial-conditioned media; IgG; immunoglobulin G; IP; immunoprecipitate; MOE; MTSS1 overexpression; M
The role of CXCL12 in tumor microenvironment
Keywords: فیبروبلاست وابسته به سرطان; CXCL12; C-X-C motif chemokine ligand 12; TME; tumor microenvironment; GPCR; G protein coupled receptor; CXCR4; chemokine receptor 4; CXCR7; chemokine receptor 7; VCAM-1; vascular cell adhesion molecule-1; VEGF; vascular endothelial growth factor; MMP; mat
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Keywords: فیبروبلاست وابسته به سرطان; Lung inflammation; lung adenocarcinoma; fibroblastic reticular cells; tumor microenvironment; ADC; Adenocarcinoma; APC; Allophycocyanin; CAF; Cancer-associated fibroblast; DC; Dendritic cell; DT; Diphtheria toxin; ECM; Extracellular matrix; EpCAM; Epithel
Redox control of cancer cell destruction
Keywords: فیبروبلاست وابسته به سرطان; ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r
TGFβ pathway inhibition in the treatment of non-small cell lung cancer
Keywords: فیبروبلاست وابسته به سرطان; ALK; Anaplastic leukemia kinase; CAF; Cancer-associated fibroblast; EGFR; Epidermal growth factor receptor; EMT; Epithelial-to-mesenchymal transition; MSC; Mesenchymal stem cell; NK Cell; Natural killer cell; NSCLC; Non-small cell lung cancer; OS; Overall
A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment
Keywords: فیبروبلاست وابسته به سرطان; A2aR; adenosine A2a receptor; CAF; cancer-associated fibroblast; CHO; Chinese hamster ovary; IC50; concentration of compound that displaces the binding of radioligand by 50%; Kb; binding constant; Ki; inhibition constant; NECA; 5â³-N-ethylcarboxamidoaden
CAR T-cell therapy for lung cancer and malignant pleural mesothelioma
Keywords: فیبروبلاست وابسته به سرطان; ACT; adoptive cell therapy; ADC; adenocarcinoma; ALK; anaplastic lymphoma kinase; CAF; cancer-associated fibroblast; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DNR; dominant negative
Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy
Keywords: فیبروبلاست وابسته به سرطان; Cancer-associated fibroblast; Cytokines; Intermediate metabolite; Autophagy; Tumor relapse; Radiation therapy; CAFs; cancer-associated fibroblasts; IGF1/2; insulin-like growth factor 1/2; CXCL12; C-X-C motif chemokine ligand 12; ROS; reactive oxygen speci
FAP positive fibroblasts induce immune checkpoint blockade resistance in colorectal cancer via promoting immunosuppression
Keywords: فیبروبلاست وابسته به سرطان; Colorectal cancer; Cancer-associated fibroblast; Fibroblast activation protein-alpha; Immune checkpoint blockade; CCL2;
Unravelling the pharmacologic opportunities and future directions for targeted therapies in gastro-intestinal cancers Part 1: GI carcinomas
Keywords: فیبروبلاست وابسته به سرطان; 5FU; 5-fluorouracil; 95%CI; 95% confidence interval; α-SMA; α-smooth muscular actin; ADC; antibody-drug conjugate; ATP; adenosine triphosphate; BSC; best supportive care; CAF; cancer-associated fibroblast; CapIri; capecitabine plus irinotecan; CapOx; ca
Annexin A1 influences in breast cancer: Controversies on contributions to tumour, host and immunoediting processes
Keywords: فیبروبلاست وابسته به سرطان; ALH; atypical lobular hyperplasia; BC; breast cancer; BEC; blood endothelial cell; BL; basal-like; CAF; cancer-associated fibroblast; DC; dendritic cells; DCIS; ductal carcinoma in situ; EAE; experimental autoimmune encephalomyelitis; EMT; epithelial-mese
Dependence of fibroblast infiltration in tumor stroma on type IV collagen-initiated integrin signal through induction of platelet-derived growth factor
Keywords: فیبروبلاست وابسته به سرطان; Cancer-associated fibroblast; Type IV-α1 collagen; Integrin; Platelet-derived growth factor A; Tumor growth
The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia
Keywords: فیبروبلاست وابسته به سرطان; ADA; adenosin deaminase; CAF; cancer-associated fibroblast; CBM; caveolin binding motif; FAPα; fibroblast activated protein alpha; Fc; fold change; LC-MS/MS; liquid chromatography-tandem mass spectrometry; IP; immunoprecipitation; QUICK; quantitative i
TGF-beta in CAF-mediated tumor growth and metastasis
Keywords: فیبروبلاست وابسته به سرطان; TGF-beta; Tumor microenvironment; Cancer-associated fibroblast; Metastasis; Stroma
Lung Cancer-Associated Myofibroblasts Reveal Distinctive Ultrastructure and Function
Keywords: فیبروبلاست وابسته به سرطان; Cancer-associated fibroblast; Electron microscopy; Tumor stroma; Smoking;
Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin
Keywords: فیبروبلاست وابسته به سرطان; Colorectal cancer; Cancer-associated fibroblasts; Migration; Claudin-11; SILAC; CAF; cancer-associated fibroblast; CALD; caldesmon; CLN11; claudin 11; CM; conditioned media; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition; ICC; immuno
Mesenchymal stem cells in non-small cell lung cancer-Different from others? Insights from comparative molecular and functional analyses
Keywords: فیبروبلاست وابسته به سرطان; Non-small cell lung cancer; Mesenchymal stem cell; Cancer-associated fibroblast; Tumor microenvironment; Cancerogenesis; Drug resistance;
Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma
Keywords: فیبروبلاست وابسته به سرطان; Cancer-Associated Fibroblasts; Distal Cholangiocarcinoma; Intrahepatic Cholangiocarcinoma; Molecular Pathogenesis; α-SMA; α-smooth muscle actin; CA19-9; carbohydrate antigen 19-9; CAF; cancer-associated fibroblast; CCA; cholangiocarcinoma; CT; computed
Hepatocellular carcinoma cells cause different responses in expressions of cancer-promoting genes in different cancer-associated fibroblasts
Keywords: فیبروبلاست وابسته به سرطان; Cancer-associated fibroblast; Gene expression; Hepatocellular carcinoma; Migration; Proliferation
Cancer-associated fibroblasts up-regulate CCL2, CCL26, IL6 and LOXL2 genes related to promotion of cancer progression in hepatocellular carcinoma cells
Keywords: فیبروبلاست وابسته به سرطان; Cancer-associated fibroblast; Hepatocellular carcinoma; InvasionCAF, Cancer-associated fibroblast; HCC, Hepatocellular carcinoma; RT-PCR, Reverse transcriptase-polymerase chain reaction
Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy
Keywords: فیبروبلاست وابسته به سرطان; Fibroblast; Cancer-associated fibroblast; p53; Tumor cell–stromal cell interaction; Breast; Neoadjuvant therapy
Tumor-stroma co-evolution in prostate cancer progression and metastasis
Keywords: فیبروبلاست وابسته به سرطان; AR; androgen receptor; ARCaP; androgen refractory prostate cancer; β2M; β2-microglobulin; BDNF; brain derived neurotropic factor; BMP; bone morphogenetic protein; BSP; bone sialoprotein; CAF; cancer-associated fibroblast; CCL5; chemokine (C-C) ligand
Hallmarks of cancer: Interactions with the tumor stroma
Keywords: فیبروبلاست وابسته به سرطان; Cancer; Tumor stroma; Cancer-associated fibroblast; Pericyte; Targeted therapy
Stroma in breast development and disease
Keywords: فیبروبلاست وابسته به سرطان; E; embryonic day; ECM; extracellular matrix; FGF; fibroblast growth factor; PTHrP; parathyroid hormone related peptide; TEB; terminal end bud; ER; estrogen receptor; EGFR; epidermal growth factor receptor; GH; growth hormone; IGF; insulin-like growth fact
Involvement of stromal p53 in tumor-stroma interactions
Keywords: فیبروبلاست وابسته به سرطان; CAF; cancer-associated fibroblast; ECM; extracellular matrix; IL; interleukin; LOH; loss of heterozygosity; MMP; matrix metalloproteinase; SDF-1; stromal derived factor 1; Tsp-1; thrombospondin-1; wt; wild-type; Stroma; Cancer; p53; Cancer-associated-fibr