دانلود مقالات ISI درباره Catechol-O-Methyltransferase + ترجمه فارسی

Association between COMT genotype and the control of memory guided saccades: Individual differences in healthy adults reveal a detrimental role of dopamine

Keywords: COMT; catechol-O-methyltransferase; Val; valine; Met; methionine; DNA; deoxyribonucleic acid; dlPFC; dorsolateral prefrontal cortex; SC; superior colliculus; FEF; frontal eye fields; SEF; supplementary eye fields; LIP; lateral intraparietal area; Memory g

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Physiologic and Psychologic Risk Factors in Central Serous Chorioretinopathy

Keywords: CI; confidence interval; COMT; catechol-O-methyltransferase; CSCR; central serous chorioretinopathy; HPA; hypothalamic-pituitary-adrenal; OR; odds ratio; RPE; retinal pigment epithelium;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperTs1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism

Keywords: Down syndrome; Animal model; Behavioral analysis; Hyperactivity; Sociability; Monoamine; Dopamine; Serotonin; Catechol-O-methyltransferase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Conversion to carbidopa and levodopa extended-release (IPX066) followed by its extended use in patients previously taking controlled-release carbidopa-levodopa for advanced Parkinson's disease

Keywords: AEs; adverse events; CD; carbidopa; CGI; Clinical Global Impression; COMT; catechol-O-methyltransferase; CR; controlled-release; C-SSRS; Columbia-Suicide Severity Rating Scale; IR; immediate-release; LD; levodopa; MAO; monoamine oxidase; OPDM; Objective P

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics

Keywords: NMDA; N-methyl-d-aspartate; DISC-1; disrupted in schizophrenia 1; PCP; phencyclidine; GRIK4; glutamate receptor, ionotropic, kainate, type 4; MAOB; monoamine oxidase B; APOA1; apolipoprotein A1; MEK2; dual-specificity mitogen-activated protein kinase kina

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2017 سفارش ترجمه

Association between polymorphism of COMT gene (Val158Met) with Alzheimer's disease: An updated analysis

Keywords: Catechol-o-methyltransferase; COMT; Genetic polymorphism; Alzheimer's disease; Neurodegenerative disease; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Catechol-O-methyltransferase (COMT) gene modulates private self-consciousness and self-flexibility

Keywords: Private self-consciousness; Public self-consciousness; Self-flexibility; Dopamine; Catechol-O-methyltransferase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Catechol-O-methyltransferase gene variants may associate with negative symptom response and plasma concentrations of prolactin in schizophrenia after amisulpride treatment

Keywords: AR1; autoregression of an order-1; COMT; catechol-O-methyltransferase; DSM-IV-TR; diagnostic and statistical manual of mental disorders, fourth edition, text revision; LD; linkage disequilibrium; MMRM; mixed model for repeated-measures; PANSS; positive an

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A highly selective fluorescent probe for sensing activities of catechol-O-methyltransferase in complex biological samples

Keywords: COMT; catechol-O-methyltransferase; SAM; S-adenosyl-l-methionine; DHMC; 7,8-dihydroxy-4-methylcoumarin; HMMC; 7-hydroxy-8-methoxy-4-methylcoumarin; 7-MHMC; 7-methoxy-8-hydroxy-4-methylcoumarin; hLS9; human liver S9; Catechol-O-methyltransferase; Fluoresce

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Allelic variation of the COMT gene in a despotic primate society: A haplotype is related to cortisol excretion in Macaca fuscata

Keywords: Macaca fuscata; Catechol-O-methyltransferase; Single nucleotide polymorphism; Cortisol excretion; Aggression; Social rank; Non-invasive genotyping;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Epigallocatechin gallate and mitochondria-A story of life and death

Keywords: ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of soybean ingestion on pharmacokinetics of levodopa and motor symptoms of Parkinson's disease - In relation to the effects of Mucuna pruriens

Keywords: Parkinson's disease; Soybean; Levodopa; Catechol-O-methyltransferase; Dyskinesia; Wearing-off;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

The COMT val158met polymorphism in ultra-endurance athletes

Keywords: Behavior; Novelty seeking; Catechol-o-methyltransferase; Ultra-endurance;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

The catechol-O-methyltransferase inhibitory potential of Z-vallesiachotamine by in silico and in vitro approaches

Keywords: Monoterpene indole alkaloids; Vallesiachotamine; Catechol-O-methyltransferase; Docking; Neurodegenerative diseases

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Association of the COMT synonymous polymorphism Leu136Leu and missense variant Val158Met with mood disorders

Keywords: Catechol-O-methyltransferase; Major depressive disorder; Bipolar disorder; Genetic risk determinants; Leu136Leu; Val158Met

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The catechol-O-methyltransferase inhibitor, tolcapone, increases the bioavailability of unmethylated (-)-epigallocatechin-3-gallate in mice

Keywords: AUC; area under the curve; CI; confidence interval; COMT; catechol-O-methyltransferase; DiMeEGCG; 4′,4″-di-O-methyl-(-)-epigallocatechin-3-gallate; EGCG; (-)-epigallocatechin-3-gallate; GTP; green tea polyphenol; i.g; intragastric; LC-MS; liquid chr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Transcranial Direct Current Stimulation (tDCS)/Transcranial Alternating Current Stimulation (tACS)Original ArticleThe COMT Val/Met Polymorphism Modulates Effects of tDCS on Response Inhibition

Keywords: Genetics; Catechol-O-methyltransferase; COMT; Dopamine; Response inhibition; Brain stimulation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Catechol-O-Methyltransferase Inhibits Colorectal Cancer Cell Proliferation and Invasion

Keywords: Colorectal cancer; Catechol-O-Methyltransferase; Xenograft model; COMT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Catechol-O-methyltransferase, dopamine, and sleep-wake regulation

Keywords: Catechol-O-methyltransferase; Genetics; Dopamine; Catecholamines; Vigilance; Narcolepsy; Performance; Pharmacogenetic; Prefrontal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

DNA methylation in schizophrenia: progress and challenges

Keywords: Schizophrenia; Epigenetics; DNA methylation; Reelin; Catechol-O-methyltransferase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Synergistic associations of catechol-O-methyltransferase and brain-derived neurotrophic factor with executive function in aging are selective and modified by apolipoprotein E

Keywords: Aging; Executive function; Apolipoprotein E; Catechol-O-methyltransferase; Brain-derived neurotrophic factor; Victoria longitudinal study;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

MTHFR: Genetic variants, expression analysis and COMT interaction in major depressive disorder

Keywords: Methylenetetrahydrofolate reductase; Catechol-O-methyltransferase; Major depressive disorder; Treatment resistant depression; Transcriptional analyses; Fibroblasts;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research reportDopamine bioavailability in the mPFC modulates operant learning performance in rats: An experimental study with a computational interpretation

Keywords: COMT; catechol-O-methyltransferase; mPFC; medial prefrontal cortex; lPFC; dorsolateral prefrontal cortex; DA; dopamine; LTP; long term potentiation; LTD; long term depression; VTA; ventral tegmental area; TD; temporal difference algorithm; BG; basal gangl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Epistatic interaction of BDNF and COMT on the frontostriatal system

Keywords: ACC; anterior cingulate; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; COMT; catechol-O-methyltransferase; DA; dopamine; fMRI; functional magnetic resonance imaging; FWE; family-wise-error; MANCOVA; multivariate analysis of covaria

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Catechol-O-methyltransferase inhibition alters pain and anxiety-related volitional behaviors through activation of β-adrenergic receptors in the rat

Keywords: βARs; β-adrenergic receptors; COMT; catechol-O-methyltransferase; catecholamines; hyperalgesia; allodynia; anxiety; thermal place preference; operant;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

Keywords: 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3′,5′-cyclic adenosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management

Keywords: AC; adenylate cyclase; AR; adrenergic receptor; CB; cannabinoid; COMT; catechol-O-methyltransferase; EP3; prostaglandin E receptor 3; GI; gastrointestinal; GPCR; G protein-coupled receptor; 5-HT; 5-hydroxytryptamine; IBNtxA; iodobenzoylnaltrexamide; IBS

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Epistasis effects of COMT and MTHFR on inter-individual differences in mental health: Under the inverted U-shaped prefrontal dopamine model

Keywords: MHI-5; five-item Mental Health Inventory; COMT; catechol-O-methyltransferase; MTHFR; methylenetetrahydrofolate reductase; PFC; prefrontal cortex; SNP; single nucleotide polymorphism; Genetic polymorphisms; COMT haplotypes; MTHFR C677T; Epistasis; Inverted

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Association analysis of COMT/MTHFR polymorphisms and major depressive disorder in Chinese Han population

Keywords: Catechol-O-methyltransferase; Methylenetetrahydrofolate reductase; Polymorphism; Major depressive disorder; Antidepressant response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Factors affecting cognitive remediation response in schizophrenia: The role of COMT gene and antipsychotic treatment

Keywords: Schizophrenia; Cognitive remediation; Genetics; Catechol-O-methyltransferase; Clozapine;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The SEMA5A gene is associated with hippocampal volume, and their interaction is associated with performance on Raven's Progressive Matrices

Keywords: SEMA5A; semaphorin 5A; RPM; Raven's Progressive Matrices; RAPM; Raven's Advanced Progressive Matrices; SNP; single nucleotide polymorphism; ICV; intracranial volume; PET; positron emission tomography; MAF; minor allele frequency; HWE; Hardy-Weinberg equ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Association of gene polymorphisms encoding dopaminergic system components and platelet MAO-B activity with alcohol dependence and alcohol dependence-related phenotypes

Keywords: MAO-B; monoamine oxidase type B; COMT; catechol-o-methyltransferase; DRD4; dopamine receptor D4; DAT; dopamine transporter; DBH; dopamine beta-hydroxylase; SNP; single nucleotide polymorphism; VNTR; variable number of tandem repeats; Alcohol dependence; A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Development of fed-batch profiles for efficient biosynthesis of catechol-O-methyltransferase

Keywords: Biosynthesis; Catechol-O-methyltransferase; Fed-batch; Parkinson's disease, Cell viability

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Immunomodulation by the estrogen metabolite 2-methoxyestradiol

Keywords: E2; 17β-Estradiol; 2me2; 2-Methoxyestradiol; COMT; Catechol-O-methyltransferase; ERs; Estrogen receptors; ERE; Estrogen response elements; ovx; Ovariectomized; orx; Orchidectomized; RA; Rheumatoid arthritis; SERM; Selective estrogen receptor modulators;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway

Keywords: 3-MT; 3-methoxytyramine; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; BDNF; brain derived neurotrophic factor; COMT; catechol-O-methyltransferase; DOPAC; 3,4-dihydroxyphenylacetic acid; DRD1; dopamine receptor D1; DRD5; dopamine receptor D5; DARPP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Developing zebrafish models relevant to PTSD and other trauma- and stressor-related disorders

Keywords: BDNF; brain-derived neurotrophic factor; COMT; catechol-O-methyltransferase; CRF; corticotropin releasing factor; HTS; high-throughput screens; HPA; hypothalamic-pituitary-adrenal; HPI; hypothalamic-pituitary-interrenal; LSD; lysergic acid diethyl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone

Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroepigenetics of stress

Keywords: 5-HT; Serotonin; ACTH; adrenocorticotropic hormone; AVP; arginine-vasopressin; BDNF; brain-derived neurotrophic factor; BLA; basolateral amygdala; COMT; catechol-O-methyltransferase; CpG; cytosine-guanine dinucleotides; CRH; corticotropin-releasing hormon

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release

Keywords: Enzyme active site structure; Presynaptic inhibition; Exocytotic and non-exocytotic release; Neuroprotection; Parkinson's disease; Affective disorders; MAO; monoamine oxidase; MAO-A; monoamine oxidase isoform A; MAO-B; monoamine oxidase isoform B; COMT; c

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM)

Keywords: COMT gene; catechol-O-methyltransferase gene; ULM; uterine leiomyoma; COMT; Catechol-O-methyltransferase; GWA; genome-wide association; OR; odds ratio; CI; confidence interval; Z; Z value for Q statistic; p; p-value for Q statistic; I; I statistic for het

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Opposite effects of tolcapone on amphetamine-disrupted startle gating in low vs. high COMT-expressing rat strains

Keywords: Amphetamine; Dopamine; Catechol-O-methyltransferase; Prepulse inhibition; Schizophrenia; Strain - tolcapone;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Distribution of the Val108/158Met polymorphism of the COMT gene in healthy Mexican population

Keywords: COMT; catechol-O-methyltransferase; SNP; single nucleotide polymorphism; PFC; prefrontal cortex; Val108/158Met; Mexican population; COMT gene; Distribution;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The ADH1B and DRD2 gene polymorphism may modify the protective effect of the ALDH2 gene against heroin dependence

Keywords: 5-HIAA; 5-hydroxyindole-3-acetic acid; 5-HIAL; 5-hydroxyindole-3-acetaldehyde; 5-HTOL; 5-hydroxytryptophol; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; COMT; catechol-O-methyltransferase; DBH; Dopamine Beta-Hydroxylase; DOPAC; 3,4-dihydroxyp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The DOPA decarboxylase (DDC) gene is associated with alerting attention

Keywords: DDC; DOPA decarboxylase; ANT; attention network test; DRD4; dopamine D4 receptor; MAOA; monoamine oxidase a; TPH 2; tryptophan hydroxylase 2; COMT; catechol-o-methyltransferase; DAT 1; dopamine transporter; ADHD; attention-deficit/hyperactivity disorder;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic signature of panic disorder: A role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?

Keywords: SME; epigenetic sequencing methylation analysis software; COMT; catechol-O-methyltransferase; DNMT1; DNA-methyltransferase 1; GABA; gamma-aminobutyric acid; GAD; glutamate decarboxylase; HAB; high anxiety-related behavior; methQTL; methylation quantitativ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The role of catechol-O-methyltransferase in catechol-enhanced erythroid differentiation of K562 cells

Keywords: ALAS2; δ-aminolevulinate synthase 2; COMT; catechol-O-methyltransferase; COX; cyclooxygenase; DNMT; DNA methyltransferase; Hb; hemoglobin; HPLC; high performance liquid chromatography; NF-κB; nuclear factor κB; PBGD; porphobilinogen deaminase; PBS; pho

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Research reportAuditory event-related potentials (P3a, P3b) and genetic variants within the dopamine and serotonin system in healthy females

Keywords: ERP; event-related potential; EEG; electroencephalogram; DA; dopamine; DAT; dopamine transporter; COMT; catechol-O-methyltransferase; 5HT; serotonin; 5HTT; serotonin transporter; 5HTTLPR; serotonin transporter long polymorphic region; VNTR; variable numbe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

ReviewForebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats

Keywords: Catechol-O-methyltransferase; Isolation rearing; Medial prefrontal cortex; Nucleus accumbens; Prepulse inhibition; Schizophrenia;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Dopamine but not l-dopa stimulates neural glutathione metabolism. Potential implications for Parkinson's and other dopamine deficiency states

Keywords: l-dopa; l-3,4-dihydroxyphenylalanine; AADC; aromatic l-amino acid decarboxylase; BH4; tetrahydrobiopterin; ROS; reactive oxygen species; GSH; reduced glutathione; GSSG; glutathione disulphide; FBS; foetal bovine serum; DOPAC; 3,4-dihydroxyphenylacetic aci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Epistasis effects of dopamine genes on interval timing and reward magnitude in humans

Keywords: Catechol-o-methyltransferase; D2 dopamine receptor; Dopamine transporter; Interval timing; Peak procedure; Reward processing;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه