دانلود مقالات ISI درباره cdk6 + ترجمه فارسی

اثرات شستشوهای اولویتدار فتالات که در اولویت قرار دارند، با قرار گرفتن در معرض قرار گرفتن در معرض دوزهای پایین در سمیت تولید مثل در مردان در موش صحرایی

Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats

Keywords: cdk6; Phthalate esters; Long-term low-dose exposure; Reproductive toxicity; Steroidogenesis; Cell cycle; Apoptosis; 17β-HSD; 17 beta hydroxy steroid dehydrogenase; BBP; butyl benzyl phthalate; Cdc2; cell division cycle gene 2; CDK6; cyclin dependent kinase 6;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

سازگاری و یادگیری شبکه های مولکولی به عنوان توصیف توسعه سرطان در سطح سیستم: استفاده بالقوه در درمان ضد سرطان

Adaptation and learning of molecular networks as a description of cancer development at the systems-level: Potential use in anti-cancer therapies

Keywords: cdk6; BRAF; B-Raf protein; BRD4; bromodomain-containing protein 4; CDK6; cyclin-dependent kinase 6; ERBB1; epidermal growth factor receptor; ERG; ETS-family oncogenic transcription factor; ERK; extracellular signal regulated protein kinase; FOS; FBJ murine oste

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

متیلاسیون ژن در سرطان معده

Gene methylation in gastric cancer

Keywords: cdk6; 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; ADAMTS9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; ARID1A; AT rich interactive domain 1A (SWI-like); AML; Acute myelocytic leukemia; ATBF1; A

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2013 سفارش ترجمه

KIAA0101 inhibition suppresses cell proliferation and cell cycle progression by promoting the interaction between p53 and Sp1 in breast cancer

Keywords: cdk6; KIAA0101; CCNE2; CDK6; CDKN1A; Sp1; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

The reciprocal link between EVI1 and miRNAs in human malignancies

Keywords: cdk6; EVI1; ecotropic virus integration site-1; MiR; microRNA; 3′-UTR; 3′-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Hyperoside and let-7a-5p synergistically inhibits lung cancer cell proliferation via inducing G1/S phase arrest

Keywords: cdk6; SCLC; small-cell lung cancer; NSCLC; non-small-cell lung cancer; miRNA; microRNA; 3′UTR; 3′untranslated region; 5′UTR; 5′untranslated region; CDS; coding sequence; CDK6; cyclin-dependent kinase 6; CDK4; cyclin-dependent kinase 4; CCND1; cyclin D1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells

Keywords: cdk6; Human B cells; Class switching; Germinal Centre; miRNA; miR-29b; Activation Induced Cytidine Deaminase; AID; IgE; Naive B cells; CDK6; EIF4E2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A selective cyclin-dependent kinase 4, 6 dual inhibitor, Ribociclib (LEE011) inhibits cell proliferation and induces apoptosis in aggressive thyroid cancer

Keywords: cdk6; Thyroid cancer; LEE011; Retinoblastoma protein (RB); CDK4; CDK6;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107

Keywords: cdk6; SA-β gal; senescence-associated beta galactosidase; MTOR; mammalian target of rapamycin; 4EBP1; eIF4E binding protein 1; S6K1; S6 kinase 1; miRNA; microRNA; RISC; RNA-induced silencing complex; UTR; un-translated region; HUVEC; human umbilical vein endot

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Juvenile hormone promotes locust fat body cell polyploidization and vitellogenesis by activating the transcription of Cdk6 and E2f1

Keywords: cdk6; Juvenile hormone; Cdk6; E2f1; Endocycle; Polyploidy; Vitellogenesis;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Reduced state transition barrier of CDK6 from open to closed state induced by Thr177 phosphorylation and its implication in binding modes of inhibitors

Keywords: cdk6; CDK6; Molecular dynamics simulations; State transition; Binding modes;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of microRNAs on ischemic stroke: From pre- to post-disease

Keywords: cdk6; AAV; adeno-associated virus; ABCA1; ATP-binding cassette transporter 1; AGO; argonaute; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; AT1R; angiotensin II type 1 receptor; AQPs; aquaporins; BBB; blood-brain barrier; Bcl-6; B-cell lymphoma-6;

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-27a-3p affects estradiol and androgen imbalance by targeting Creb1 in the granulosa cells in mouse polycytic ovary syndrome model

Keywords: cdk6; miRNA; microRNA; miR-27-3p; microRNA-27a-3p; mGC; mouse granulosa cell; E2; estradiol; GC; granulosa cell; Creb1; cyclic AMP response element (CRE)-binding protein 1; Cyp19a1; cytochrome P450 family 19 subfamily A polypeptide 1; DHT; dihydrotestosterone;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticlemiR-218 suppresses gastric cancer cell cycle progression through the CDK6/Cyclin D1/E2F1 axis in a feedback loop

Keywords: cdk6; miR-218; E2F1; CDK6; Cyclin D1; Gastric cancer;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment Rationale and Study Design for the JUNIPER Study: A Randomized Phase III Study of Abemaciclib With Best Supportive Care Versus Erlotinib With Best Supportive Care in Patients With Stage IV Non-Small-Cell Lung Cancer With a Detectable KRAS Mutati

Keywords: cdk6; Biomarkers; CDK4; CDK6; Cyclin-dependent kinase; LY2835219;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperFerulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro

Keywords: cdk6; FA; Ferulic acid; CCND1; Cyclin D1; CDK4; Cyclin Dependent Kinase 4; CDK6; Cyclin Dependent Kinase 6; RB; Retinablastoma gene; BCL-XL; B-cell lymphoma-extra large; BID; BH3 Interacting Domain Death Agonist; DR4; HLA-DR4; DR5; Death receptor 5; FADD; Fas-A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-33 promotes the replicative senescence of mouse embryonic fibroblasts by suppressing CDK6

Keywords: cdk6; MicroRNA-33; Cellular senescence; CDK6; Proliferation; MEFs; Mouse Embryonic Fibroblasts; SA-β-gal; Senescence-associated β-galactosidase staining; CDK6; cyclin-dependent protein kinase 6;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Nanog interact with CDK6 to regulates astrocyte cells proliferation following spinal cord injury

Keywords: cdk6; Nanog; CDK6; Spinal cord; Astrocyte; Proliferation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ANRIL lncRNA triggers efficient therapeutic efficacy by reprogramming the aberrant INK4-hub in melanoma

Keywords: cdk6; Melanoma; Therapeutic efficacy; ANRIL; INK4A; INK4B; lncRNAs; long non-coding RNAs; siRNA; small interfering RNA; PCR; polymerase chain reaction; RPE; retinal pigment epithelial; GFP; green fluorescence protein; NST; melanoma-neural system tumor; CDK4;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

Keywords: cdk6; API5; apoptosis inhibitor 5; ARF1; ADP ribosylation factor 3; BCA; bicinchoninic acid; BBC3/PUMA; BCL2 binding component 3; BIRC5; baculoviral IAP (inhibitor of apoptosis) repeat containing 5; CDC25A; cell division cycle 25A; CDK4; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

TDP-43/FUS in motor neuron disease: Complexity and challenges

Keywords: cdk6; AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2016 سفارش ترجمه

microRNA-26a and -584 inhibit the colorectal cancer progression through inhibition of the binding of hnRNP A1-CDK6 mRNA

Keywords: cdk6; microRNA; Colon cancer; hnRNP A1; CDK6;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA in prostate cancer

Keywords: cdk6; DGCR8; Digeorge syndrome chromosomal region 8; CCNDs; cyclin Ds; CDK4; cyclin-dependent kinase 4; CDK6; cyclin-dependent kinase 6; E2F; E2 transcription factor; E2F2; E2 transcription factor 2; IGF1R; insulin-like growth factor 1 receptor; ELK1; ELK1 memb

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective effect of microRNA-99a against focal cerebral ischemia–reperfusion injury in mice

Keywords: cdk6; MiR-99a; Cerebral ischemia; Oxidative stress; Cell cycle; Cyclin D1; CDK6

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-494 inhibits the growth and angiogenesis-regulating potential of mesenchymal stem cells

Keywords: cdk6; microRNAs; miRNAs or miRs; miR-494; microRNA-494-3p; MSCs; mesenchymal stem cells; dMSCs; decidua-derived MSCs; PE; preeclampsia; mi-494; miR-494 mimic; mi-NC; miR-494 mimic negative control; si-RNA; small interfering RNA; VEGF; vascular endothelial growt

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells

Keywords: cdk6; 6His; hexahistidine tag; aa; amino acids; Bcl-2; apoptosis regulator B-cell CLL/lymphoma 2; cAMP; cyclic adenosine monophosphate; CCNC; cyclin C; CCPG1; cell cycle progression protein 1; CDK6; cyclin-dependent kinase 6; cDNA; coding DNA; CXCR4; chemokine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Original StudymiR Profiling Identifies Cyclin-Dependent Kinase 6 Downregulation as a Potential Mechanism of Acquired Cisplatin Resistance in Non-Small-Cell Lung Carcinoma

Keywords: cdk6; CDK6; Cell cycle inhibition; microRNA; NSCLC; Predictive biomarkers;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth

Keywords: cdk6; OS; osteosarcoma; miR or miRNA; microRNA; ncRNA; noncoding RNA; miR-34a; microRNA-34a; pre-miR-34a or mir-34a; pre-microRNA-34a; tRNA/mir-34a; transfer RNA fusion pre-miR-34a; CDK6; cyclin-dependent kinase 6; c-MET; hepatocyte growth factor receptor; SIRT

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Increasing progranulin levels and blockade of the ERK1/2 pathway: Upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia

Keywords: cdk6; FTLD-TDP; Lymphocytes; Cell proliferation; Progranulin; ERK1/2; CDK6;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers

Keywords: cdk6; FTLD-TDP; Lymphocytes; Cell proliferation; CDK6; Wnt5a signaling; Pertussis toxin;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

A new goniothalamin N-acylated aza-derivative strongly downregulates mediators of signaling transduction associated with pancreatic cancer aggressiveness

Keywords: cdk6; Goniothalamin; N-acylated aza-derivatives; Pancreatic cancer; Panc-1 cells; AXL kinase; HIF-1α; GSH; glutathione; AXL; tyrosine-protein kinase receptor; ERK1/2; extracellular signal-regulated kinases 1 and 2; HIF-1α; hypoxia-inducible factor-1α; ROS;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

P53-induced microRNA-107 inhibits proliferation of glioma cells and down-regulates the expression of CDK6 and Notch-2

Keywords: cdk6; Glioma; P53; miR-107; CDK6; Notch-2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Growth inhibitory effects of three miR-129 family members on gastric cancer

Keywords: cdk6; miRNAs; microRNAs; UTR; untranslated region; CDK6; cyclin dependent kinase 6; SOX4; sex determining region Y-box 4; FRA7H; fragile site on human chromosome 7; RB1; retinoblastoma 1; SRY; sex-determining region Y; TGF β; transforming growth factor β; RTC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6

Keywords: cdk6; miR-137; Lung cancer; Cdc42; Cdk6

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The ClC-3 chloride channel protein is a downstream target of cyclin D1 in nasopharyngeal carcinoma cells

Keywords: cdk6; Cyclin D1; ClC-3; CDK4; CDK6; Chloride channels;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation

Keywords: cdk6; microRNA; miRNA; HEKn; human epidermal keratinocytes neonatal; SA-β-gal; senescence-associated beta-galactosidase; HAT; Histone Acetyl Transferase; Keratinocytes; Senescence; Proliferation; MicroRNA-191; CDK6; SATB1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies

Keywords: cdk6; TDP-43; TAR DNA-binding protein of 43 kDa; ALS; amyotrophic lateral sclerosis; hnRNP; heterogeneous nuclear ribonucleoprotein; hNFL; human low molecular weight neurofilament; Cdk6; cyclin-dependent kinase 6; ROS; reactive oxygen species; EA; ethacrynic a

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementia

Keywords: cdk6; FTLD; Lymphocytes; Cell cycle; pRb; CDK6; TDP-43;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular characterization of a t(2;7) translocation linking CDK6 to the IGK locus in CD5− monoclonal B-cell lymphocytosis

Keywords: cdk6; Monoclonal B-cell lymphocytosis; chromosomal translocation; IGK; CDK6; long-range PCR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Znhit1 causes cell cycle arrest and down-regulates CDK6 expression

Keywords: cdk6; Zf-HIT domain; Znhit1; Cell cycle arrest; CDK6; T cell proliferation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular mechanism of cell proliferation in rodent uterus during the estrous cycle

Keywords: cdk6; Uterus; Estrous cycle; Cyclin's D; cdk4; cdk6; Estrogen receptor; c-fos;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

Keywords: cdk6; miRNA, microRNA; 3′-UTR, 3′-untranslated region; mRNA, messenger RNA; CCND1, cyclin D1; CCND3, cyclin D3; CCNE2, cyclin E2; CDK4/6, cyclin-dependent kinase 4/6; MET, hepatocyte growth factor receptorMicroRNA; miR-34a; CCND1; CDK6; Cell cycle

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

In silico analysis of structural and functional consequences in p16INK4A by deleterious nsSNPs associated CDKN2A gene in malignant melanoma

Keywords: cdk6; Malignant melanoma; Single nucleotide polymorphism; CDKN2A gene; p16INK4A; cdk6

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure

Keywords: cdk6; CDK inhibitor; CDK1; CDK2; CDK4; CDK6; X-ray; CDK4 mimic CDK4; E2F

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Seven Novel and Stable Translocations Associated with Oncogenic Gene Expression in Malignant Melanoma

Keywords: cdk6; Melanoma; oncogenic gene expression; translocation; CDK6; siRNA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

NMR and mass spectrometry studies of putative interactions of cell cycle proteins pRb and CDK6 with cell differentiation proteins MyoD and ID-2

Keywords: cdk6; MyoD; Id-2; Retinoblastoma protein; CDK6; Interaction; Complex;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Biology of plasma cells

Keywords: cdk6; plasma cell; multiple myeloma; cell cycle; p18IN4c; cyclin D; Cdk6; Cdk4; Rb; IL-6; TRAIL/APO2L; CD40; BlyS; BAFF;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه