Heat shock transcription factor HSF1 regulates the expression of the Huntingtin-interacting protein HYPK
Keywords: Chaperone; Gene expression; HSF1; HYPK; Stress response;
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Protein export through the bacterial flagellar type III export pathway
Keywords: Bacterial flagellum; Flagellar assembly; Type III protein export; ATPase; Chaperone; Proton motive force;
The chaperone FdsC for Rhodobacter capsulatus formate dehydrogenase binds the bis-molybdopterin guanine dinucleotide cofactor
Keywords: Molybdenum cofactor; l-cysteine desulfurase; Formate dehydrogenase; Chaperone; bis-MGD
Identification of a novel ATPase activity in 14-3-3 proteins - Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies
Keywords: WT; wild-type; Ni-NTA; nickel-nitriloacetic acid; MALDI; matrix assisted laser desorption ionization; TOF; tandem time of flight; PDB; protein data bank; ATP-γ-S; adenosine 5â²-(3-thiotriphosphate); AMP-PCP; adenylylmethylenediphosphonate; HEPES; 4-(2-h
Crystal Structure of a Symmetric Football-Shaped GroEL:GroES2-ATP14 Complex Determined at 3.8 Å Reveals Rearrangement between Two GroEL Rings
Keywords: folding; chaperone; chaperonin; nanomachine; inter-ring contacts
Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors
Keywords: Hsp90; Anti-cancer; Chaperone; Novobiocin
Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins
Keywords: Chaperone; ER stress; Calcium ionophore; Major histocompatibility; MHC class I; Antigen presentation;
Research ReportPrefoldin prevents aggregation of α-synuclein
Keywords: Prefoldin; Chaperone; α-Synuclein; Protein aggregation; Cell death;
Induction of rainbow trout MH class I and accessory proteins by viral haemorrhagic septicaemia virus
Keywords: VHSV; Histocompatibility; Beta-2 microglobulin; Antigen presentation; Chaperone; Temperature;
Regulation of photosynthetic carbon metabolism in aquatic and terrestrial organisms by Rubisco activase, redox-modulation and CP12
Keywords: Carbon metabolism; Photosynthesis; Enzyme regulation; Protein–protein interaction; Chaperone
Cytochrome c biogenesis System I: An intricate process catalyzed by a maturase supercomplex?
Keywords: Cytochrome c maturation; Membrane supercomplex; Apocytochrome; Chaperone; Protein-protein interactions; Rhodobacter capsulatus; Photosynthesis and respiration;
Take five - Type VII secretion systems of Mycobacteria
Keywords: Protein secretion; Mycobacterium; Secretion signal; Chaperone; Protease;
Chaperone function of two small heat shock proteins from maize
Keywords: Small heat shock protein; Chaperone; Zea mays; α-Crystallin domain; Oligomerization; Transmission electron microscopy;
Dynamics of α-Hb chain binding to its chaperone AHSP depends on heme coordination and redox state
Keywords: AHSP; alpha hemoglobin-stabilizing protein; AHSPWT; recombinant human wild type AHSP with an N-terminal Gly-Pro-Leu-Gly-Ser peptide; AHSP:α-Hb; complex formed between WT α-Hb chain and recombinant human wild type AHSP; Cyt b5; recombinant soluble domain
Biogenesis and adhesion of type 1 and P pili
Keywords: Chaperone; Usher; Pilus; Donor-strand exchange; Pilicides; Macromolecular machine
Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption
Keywords: Synuclein gamma; Chaperone; HER2 signaling; Breast cancer; Therapy resistance; BCSG1; breast cancer specific gene 1; ERα; estrogen receptor α; Hsp; heat shock protein; mTOR; mammalian target of rapamycin; SNCA; synuclein α; SNCB; synuclein β; SNCG; sy
A Mutation in the Catalytic Loop of Hsp90 Specifically Impairs ATPase Stimulation by Aha1p, But Not Hch1p
Keywords: Hsp90, heat shock protein 90; HSQC, heteronuclear single quantum coherenceco-chaperone; yeast; chaperone; enzyme; Sti1p
Cobalamin-dependent dehydratases and a deaminase: Radical catalysis and reactivating chaperones
Keywords: Adenosylcobalamin; Cobalamin; Coenzyme B12; Radical enzyme; Reactivase; Chaperone
Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6
Keywords: Small heat shock protein; Chaperone; HSPB6(HSP20); X-ray crystallography; Small-angle X-ray scattering; All-atom ensemble modeling;
The chaperone like function of the nonhistone protein HMGB1
Keywords: HMGB1 protein; Chaperone; Nucleosome reconstitution; Acetylation;
Hyper-activation of foldase-dependent lipase with lipase-specific foldase
Keywords: Foldase-dependent lipase; Lipase-specific foldase; Chaperone; Organic solvent-stable enzyme; Activation; Calcium ion;
GRP78 from grass carp (Ctenopharyngodon idella) provides cytoplasm protection against thermal and Pb2+ stress
Keywords: Glucose regulated protein 78; Stress protein; Cytoplasm protection; Chaperone; Grass carp;
Structural and functional differences of cytosolic 90-kDa heat-shock proteins (Hsp90s) in Arabidopsis thaliana
Keywords: Heat shock protein 90; Chaperone; Oligomerization; Cytoplasm; Arabidopsis thaliana; Hsps; heat shock proteins; HS; heat shock; MDH; malate dehydrogenase; SEC; size-exclusion chromatography; G6PDH; glucose-6-phosphate dehydrogenase;
NMDA receptor-dependent recruitment of calnexin to the neuronal plasma membrane
Keywords: Calnexin; Chaperone; Hippocampal neurons; Endoplasmic reticulum; NMDA receptor;
Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes
Keywords: ATF; activating transcription factor; Ad-calu; adenovirus containing mouse calumenin 1 cDNA; Ad-lacZ; adenovirus containing lacZ gene; CHOP; C/EBP-homologous protein; ERAD; ER-associated degradation; eIF2; eukaryotic initiation factor 2; ERp57; the thiol
Molecular chaperone involvement in chloroplast protein import
Keywords: Chaperone; Chloroplast; Hsp70; Hsp93; Protein transport; TOC/TIC machinery;
Evidence of oxidative stress in young and aged DJ-1-deficient mice
Keywords: Parkinson's disease; DJ-1; Oxidative stress; Heat shock protein; Aging; Nigrostriatal; Chaperone;
NMNATs, evolutionarily conserved neuronal maintenance factors
Keywords: NMNAT; neurodegeneration; chaperone; NAD; proteinopathies; axonopathy; synapse; neuronal maintenance;
The combined effect of acetylation and glycation on the chaperone and anti-apoptotic functions of human α-crystallin
Keywords: Acetylation; α-Crystallin; Chaperone; Glycation; Apoptosis;
The cloning and inducible expression of the rainbow trout ERp57 gene
Keywords: Antigen presentation; Chaperone; Endogenous pathway; Protein disulphide isomerase;
Chaperone-protease networks in mitochondrial protein homeostasis
Keywords: Mitochondrion; Protein homeostasis; Quality control; Chaperone; Protease;
Small heat shock protein AgsA: An effective stabilizer of enzyme activities
Keywords: sHSP; Chaperone; AgsA; Bovine serum albumin; Stabilization; Enzyme
Biochemical characterization and cooperation with co-chaperones of heat shock protein 90 from Schizosaccharomyces pombe
Keywords: Chaperone; Hsp90; Co-chaperone; Conformational change; Schizosaccharomyces pombe
The targeting, docking and anti-proteolysis functions of the secretin chaperone PulS
Keywords: Chaperone; Outer membrane; Periplasm; Proteolysis; Secretin; Secretion
The complexity of chloroplast chaperonins
Keywords: chloroplast; chaperonin; Rubisco; protein folding; chaperone
Chaperone-independent mitochondrial translocation and protection by αB-crystallin in RPE cells
Keywords: αB-crystallin; small heat shock protein; chaperone; mitochondria; oxidative stress; RPE; retinal cells
Quality control of a molybdoenzyme by the Lon protease
Keywords: Protease; Chaperone; Protein degradation; Microbiology; Protein–protein interaction
Structural alteration of Escherichia coli Hsp31 by thermal unfolding increases chaperone activity
Keywords: Hsp31; Chaperone; Conformational change; Oligomerization; Glyoxalase
Cis-retinoids and the chemistry of vision
Keywords: Visual cycle; 11-Cis-retinal; 9-Cis-retinal; Vitamin A; Isomerase; Chaperone;
Intrinsically disordered proteins undergo and assist folding transitions in the proteome
Keywords: Disordered protein; Unstructured protein; Induced folding; Chaperone; Ubiquitin proteasome system; Ubiquitin ligase
Mini-review: Foldosome regulation of androgen receptor action in prostate cancer
Keywords: Foldosome; Chaperone; Heat shock protein; Androgen receptor; Prostate cancer; Cancer therapeutics
Autotransporter secretion: varying on a theme
Keywords: Autotransporter; Bam complex; Chaperone; Outer membrane; Protein secretion
Clusterin is a specific stabilizer and liberator of extracellular cathepsin K
Keywords: Clu, clusterin; Z-Phe-Arg-AMC, benzyloxycarbonyl-Phe-Arg-7-amino-4-methylcoumarin; DTT, dithiothreitolCysteine peptidase; Chaperone; Liberator; Enzyme stability; Extracellular proteolysis
Heat shock protein 90 from neglected protozoan parasites
Keywords: Hsp90; Chaperone; Protozoan; Plasmodium; Giardia; Trans-splicing;
HSPBs: Small proteins with big implications in human disease
Keywords: HSPB; Heat shock protein; Chaperone; Cancer; Neurodegeneration
The small heat shock proteins family: The long forgotten chaperones
Keywords: Small Heat Shock Protein; Chaperone; Chaperonopathies; HSPB;
Change in the enzymatic dual function of the peroxiredoxin protein by gamma irradiation
Keywords: Chaperone; Dual functions; Dual function engineering; Gamma irradiation; Peroxiredoxin
Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2
Keywords: Chaperone; Cmr; Iron-sulfur protein; TB; Transcription regulation; WhiB-like protein;
Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90
Keywords: Hsp90; Chaperone; Inhibitors; Indolone; Aminoquinazoline; Quinazoline; Her2; Cancer
The C-terminal α-helix of SPAS-1, a Caenorhabditis elegans spastin homologue, is crucial for microtubule severing
Keywords: AAA ATPase; Caenorhabditis elegans; Chaperone; Hereditary spastic paraplegia; Microtubule; Spastin;