Keywords: اختلال کولورکتال; CeA; central nucleus of the amygdala; CRD; colorectal distension; NTS; nucleus tractus solitarius; PENFS; percutaneous, electrical nerve field stimulator; PWT; paw withdrawal threshold; RVM; rostral ventral medulla; TNBS; trinitrobenzenesulfonic acid; VMR
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Keywords: اختلال کولورکتال; AHP; afterhyperpolarization; ANOVA; analysis of variance; AP; action potential; CNS; central nervous system; CRD; colorectal distension; CRD-NR; colorectal distension-nonresponsive; CRD-R; colorectal distension-responsive; DF; delayed firing; EPSP; excita
Keywords: اختلال کولورکتال; CRD; colorectal distension; IC; interstitial cystitis; LS; lumbosacral; PBS; Painful bladder syndrome; PNA; pelvic nerve afferent; SI; slow infusion; SRF; stimulus-response function; UBD; urinary bladder distension; VMR; viscero-motor response; GABAA; i
Keywords: اختلال کولورکتال; Colorectal distension; Experimental colitis; Maternal separation; StressNMS, neonatal maternal separation; VMR, visceromotor response; CRD, colorectal distension; TNBS, trinitrobenzene sulfonic acid; WAS, water avoidance stress; MPO, myeloperoxidase; CRF,
Keywords: اختلال کولورکتال; AHP; afterhyperpolarization; AP; action potential; CNS; central nervous system; CRD; colorectal distension; CRD-NR; CRD-non-responsive; CRD-R; CRD-responsive; DF; delayed firing; DRG; dorsal root ganglion; IB; initial bursting; IBD; inflammatory bowel dis
Keywords: اختلال کولورکتال; 5-HIAA; 5-hydroxyindoleacetic acid; BDNF; brain derived neurotrophic factor; CRD; colorectal distension; EDTA; ethylenediaminetetraacetic acid; EPM; elevated plus maze; FST; forced swim test; GF; germ-free; HPA; hypothalamic-pituitaryadrenal; HPLC; high
Keywords: اختلال کولورکتال; Granisetron(PubChem CID: 6918003); Irritable bowel syndrome; Abdominal pain; Granisetron; Colorectal distension; Ventrolateral medulla; Neurons;
Keywords: اختلال کولورکتال; 2-AG; 2-arachidonoylglycerol; CB1; cannabinoid receptor 1; CORT; corticosterone; COX-2; cyclooxygenase-2; CRD; colorectal distension; DRG; dorsal root ganglion; EMG; electromyography; GR; glucocorticoid receptor; FAAH; fatty acid amide hydrolase; HPA; hyp
Keywords: اختلال کولورکتال; Bifidobacteria; Behaviour; Cognition; Colorectal distension; BALB/c mice; Corticosterone;
Keywords: اختلال کولورکتال; Visceral Hyperalgesia; HPA; Epigenetic Modification; Pain Sensitivity; ChIP; chromatin immunoprecipitation; CNR1; cannabinoid receptor 1; CNS; central nervous system; CORT; corticosterone; CRD; colorectal distension; DNMT; DNA (cytosine-5-)-methyltransfer
Keywords: اختلال کولورکتال; Imipramine; Serotonergic receptors; Adrenergic receptors; Visceral pain; Colorectal distension; Antinociception;
Keywords: اختلال کولورکتال; ACC; anterior cingulate cortex; BLA; basolateral nucleus of the amygdala; cACC; caudal ACC; CeA; central nucleus of the amygdala; CRD; colorectal distension; IBS; irritable bowel syndrome; IL; infralimbic cortex; MS; maternally separated; NS; non separate
Keywords: اختلال کولورکتال; α2AAR; α-2A adrenergic receptor; CCK2R; cholecystokinin B/2 receptor; CRD; colorectal distension; GI; gastrointestinal; IBS; irritable bowel syndrome; IL; interleukin; LPS; lipopolysaccharide; PBS; phosphate-buffered saline; qRT-PCR; quantitative real-t
Keywords: اختلال کولورکتال; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; CRD; colorectal distension; DRG; dorsal root ganglion; DSS; dextran sodium sulfate; FSS; forced swimming stress; HeICS; heterotypic intermittent chronic stress; HRP; horse radish peroxi
The 5-HT4 receptor-mediated inhibition of visceral nociceptive neurons in the rat caudal ventrolateral medulla
Keywords: اختلال کولورکتال; 5-HT; serotonin; 5-HT4 receptors; serotonin type 4 receptors; CRD; colorectal distension; CVLM; caudal ventrolateral medulla; FGID; functional gastrointestinal disorders; RVM; rostroventral medulla; abdominal pain; 5-HT4 receptors; caudal ventrolateral me
Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome
Keywords: اختلال کولورکتال; Pain; Proteolytic Activity; Protease; PAR2; AA; arachidonic acid; CRD; colorectal distension; COX; cyclooxygenase; CYPe; cytochrome epoxygenase; DRG; dorsal root ganglia; EET; epoxyeicosatrienoic acid; FB; Fast Blue; HC; healthy control; HETE; hydroxyeico
The antinociceptive effects of intravenous tianeptine in colorectal distension-induced visceral pain in rats: The role of 5-HT3 receptors
Keywords: اختلال کولورکتال; Tianeptine; Visceral pain; Antinociception; Colorectal distension; Antidepressant; Rat
New neostigmine-based behavioral mouse model of abdominal pain
Keywords: اختلال کولورکتال; abdominal pain; analgesia; behavioral pain responses; colorectal distension; gastrointestinal disorders
Pronociceptive effect of 5-HT1A receptor agonist on visceral pain involves spinal N-methyl-d-aspartate (NMDA) receptor
Keywords: اختلال کولورکتال; AG; allylglycine; AP5; 2-amino-5-phosphonopentanoic acid; CRD; colorectal distension; DPAT; 8-hydroxy-2-(di-n-propylamino)-tetralin; GAD; γ-amino decarboxylase; [3H]-DPAT; [3H]-8-hydroxy-2-(di-n-propylamino) tetralin; i.t.; intrathecal; L6-S1; lumbo-sa
Original ResearchBasic and Translational-Alimentary TractActivation of Colonic Mucosal 5-HT4 Receptors Accelerates Propulsive Motility and Inhibits Visceral Hypersensitivity
Keywords: اختلال کولورکتال; Constipation; ATI-7505; Peristaltic Reflex; Cavitation; BAC; bacterial artificial chromosome; CRD; colorectal distension; EC; enterochromaffin; eGFP; enhanced green fluorescent protein; GFP; green fluorescent protein; GI; gastrointestinal; 5-HT; 5-hydroxy
Stress and visceral pain: From animal models to clinical therapies
Keywords: اختلال کولورکتال; ASICs; acid-sensing ion channels; BDNF; brain-derived neutrophic factor; ATP; adenosine triphosphate; CB; cannabinoid; CeA; central amygdala; CNS; central nervous system; CRD; colorectal distension; CRF; corticotropin releasing factor; CRF1; CRF receptor
Further Validation of a Model of Fibromyalgia Syndrome in the Rat
Keywords: اختلال کولورکتال; Unpredictable sound stress; visceral hyperalgesia; colorectal distension; anxiety; irritable bowel syndrome; temporomandibular disorder
Cathepsin S Is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR2-Dependent Mechanism in Mice
Keywords: اختلال کولورکتال; Activity-Based Probes; Proteases; Protease-Activated Receptors; Inflammation; Pain; ABP; activity-based probe; Cat; cathepsin; CRD; colorectal distension; DRG; dorsal root ganglia; DTT; dithiothreitol; FT; fluorescence tomography; IR; immunoreactivity/imm
Corticosterone Mediates Reciprocal Changes in CB 1 and TRPV1 Receptors in Primary Sensory Neurons in the Chronically Stressed Rat
Keywords: اختلال کولورکتال; Visceral Hyperalgesia; Visceral Motor Response; Water Avoidance Stress; Dorsal Root Ganglion; AEA; endocannabinoid anandamide; CB1; cannabinoid receptor 1; COX-2; cyclooxygenase-2; CRD; colorectal distension; CRF; corticotrophin releasing factor; CTB; chl
Role of oxidative stress in animal model of visceral pain
Keywords: اختلال کولورکتال; Colorectal distension; Glutathione peroxidase; Superoxide dismutase; Trolox
Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: A centrally mediated process
Keywords: اختلال کولورکتال; Melatonin; Colorectal distension; Visceral hyperalgesia; MT receptors;
Comparison of metabolic and neuropathy profiles of rats with streptozotocin-induced overt and moderate insulinopenia
Keywords: اختلال کولورکتال; diabetes; pre-diabetes; hyperalgesia; allodynia; insulin; hyperglycemia; CRD; colorectal distension; DPN; diffuse peripheral neuropathy; EMG; electromyographic; FG; fasting plasma glucose; FTT; food tolerance test; GTT; glucose tolerance test; HbA1c; hemo
Upper thoracic postsynaptic dorsal column neurons conduct cardiac mechanoreceptive information, but not cardiac chemical nociception in rats
Keywords: اختلال کولورکتال; c-fos-IR; c-fos immunoreactive; CN; cuneate nucleus; CPSA; cardiopulmonary sympathetic afferents; CRD; colorectal distension; DC; dorsal column; DCN; dorsal column nuclei; FE; Fluoro-Emerald; FR; Fluoro-Ruby; GN; gracile nucleus; HT; high threshold; LT; l
Evidence of Central and Peripheral Sensitization in a Rat Model of Narcotic Bowel-Like Syndrome
Keywords: اختلال کولورکتال; Visceral Pain; Glia Cells; Morphine; CRD; colorectal distension; L6-S1; lumbar 6 to sacral 1; MRT; mean retention time; NBS; narcotic bowel syndrome; nor-BNI; nor-binaltorphimine; PGP; protein gene product; RMCP; rat mast cell protease;
The GABAB receptor agonist, baclofen, and the positive allosteric modulator, CGP7930, inhibit visceral pain-related responses to colorectal distension in rats
Keywords: اختلال کولورکتال; Colorectal distension; Visceromotor response; Visceral pain; GABAB receptor; Baclofen; CGP7930
Peripheral anti-nociceptive effect of nociceptin/orphanin FQ in inflammation and stress-induced colonic hyperalgesia in rats
Keywords: اختلال کولورکتال; IBS; intestinal bowel syndrome; CRF; corticotropin-releasing factor; N/OFQ; nociceptin/orphanin/FQ; NOP receptor; nociceptin/orphanin peptide receptor; MPO; myeloperoxidase; ICV; intracerebroventricular; IP; intraperitoneal; IT; intrathecal; IC; intracolo
Sex differences in the activation of the spinoparabrachial circuit by visceral pain
Keywords: اختلال کولورکتال; Colorectal distension; Parabrachial nucleus; Opiates; Mu opioid receptor; Morphine;
Mineralocorticoid and glucocorticoid receptors in the amygdala regulate distinct responses to colorectal distension
Keywords: اختلال کولورکتال; Electrophysiology; Dorsal horn; Colorectal distension; Amygdala; Corticosterone; Glucocorticoid receptor; Mineralocorticoid receptor
Sex differences in functional brain activation during noxious visceral stimulation in rats
Keywords: اختلال کولورکتال; Visceral pain; Colorectal distension; Cerebral blood flow; Brain mapping; Sex difference;
Intraspinal sprouting of unmyelinated pelvic afferents after complete spinal cord injury is correlated with autonomic dysreflexia induced by visceral pain
Keywords: اختلال کولورکتال; distal colon; cholera toxin subunit beta; pelvic primary afferent; neuronal plasticity; CGRP; calcitonin gene-related peptide; ChAT; choline acetyltransferase; CRD; colorectal distension; CTb; cholera toxin subunit beta; DGC; dorsal gray commissure; DRG;
Colorectal distension enforce acute urinary bladder distension-induced hepatic vasoconstriction in the rat
Keywords: اختلال کولورکتال; Colorectal distension; Liver; Urinary retention; Vesicovascular reflex; Sympathetic nerve
Hind Paw Incision in the Rat Produces Long-Lasting Colon Hypersensitivity
Keywords: اختلال کولورکتال; Colorectal distension; central sensitization; somatic pain; somatovisceral convergence; visceral pain; zymosan; incision
Effect of buprenorphine on the cardiovascular and respiratory response to visceral pain in conscious rabbits
Keywords: اختلال کولورکتال; analgesia; buprenorphine; colorectal distension; rabbit; visceral pain;
Role of tachykinin NK1 and NK2 receptors in colonic sensitivity and stress-induced defecation in gerbils
Keywords: اختلال کولورکتال; Aprepitant; Saredutant; Colorectal distension; Stress; Visceral pain; Tachykinin; NK receptor; Gerbil; Colonic motility
Oral clonidine inhibits visceral pain-related viscerosomatic and cardiovascular responses to colorectal distension in rats
Keywords: اختلال کولورکتال; Autonomic responses; Cardiovascular responses; Clonidine; Colonic compliance; Colorectal distension; Visceral pain; Viscerosomatic responses
Involvement of metabotropic glutamate 5 receptor in visceral pain
Keywords: اختلال کولورکتال; Colorectal distension; Visceral pain; Visceromotor response; Colonic afferents; mGluR5; Glutamate
Regional brain activation in conscious, nonrestrained rats in response to noxious visceral stimulation
Keywords: اختلال کولورکتال; Visceral pain; Abdominal pain; Nociception; Colorectal distension; Cerebral blood flow; Brain mapping
Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms
Keywords: اختلال کولورکتال; 4α-PDD; 4 α-phorbol 12,13-didecanoate; 6-FAM; 6-carboxyfluorescein; CRD; colorectal distension; DRG; dorsal root ganglia; IBS; irritable bowel syndrome; mRNA; messenger RNA; PAR2; protease-activated receptor 2; siRNA; small interfering RNA; TRP; transie
Colorectal distension-induced pseudoaffective changes as indices of nociception in the anesthetized female rat: Morphine and strain effects on visceral sensitivity
Keywords: اختلال کولورکتال; Anesthetized; Colorectal distension; Female rat; Irritable bowel; Methods; Strain differences; Visceral pain
Spinal cord stimulation modulates intraspinal colorectal visceroreceptive transmission in rats
Keywords: اختلال کولورکتال; Visceral hypersensitivity; Irritable bowel syndrome; Colorectal distension; Spinal cord
Severity of mucosal inflammation as a predictor for alterations of visceral sensory function in a rat model
Keywords: اختلال کولورکتال; Abdominal pain; Cytokine; Colorectal distension; Inflammation; Trinitrobenzenesulfonic acid (TNBS); Visceral hyperalgesia
Assessment of Visceral Pain-Related Pseudo-Affective Responses to Colorectal Distension in Mice by Intracolonic Manometric Recordings
Keywords: اختلال کولورکتال; Colorectal distension; electromyography; manometry; mechanical recordings; mouse; visceral pain
Colonic nociception via nucleus submedius is modulated by pontine centres in the rat
Keywords: اختلال کولورکتال; Colorectal distension; Visceral nociception; Thalamus; Barrington's nucleus; Locus ceruleus;
Evaluation of pseudo-affective responses to noxious colorectal distension in rats by manometric recordings
Keywords: اختلال کولورکتال; Colorectal distension; Fentanyl; Rat; Visceral pain; Visceromotor response;
Peripheral injection of sauvagine prevents repeated colorectal distension-induced visceral pain in female rats
Keywords: اختلال کولورکتال; Antalarmin; Sauvagine; CRF; Visceral pain; Colorectal distension; Female Fisher rats;